Zobrazeno 1 - 10
of 222
pro vyhledávání: '"Mathias Winkler"'
Autor:
Amarnath Challapalli, Tara D. Barwick, Suraiya R. Dubash, Marianna Inglese, Matthew Grech-Sollars, Kasia Kozlowski, Henry Tam, Neva H. Patel, Mathias Winkler, Penny Flohr, Azeem Saleem, Amit Bahl, Alison Falconer, Johann S. De Bono, Eric O. Aboagye, Stephen Mangar
Publikováno v:
Molecules, Vol 28, Iss 24, p 8018 (2023)
Malignant transformation is characterised by aberrant phospholipid metabolism of cancers, associated with the upregulation of choline kinase alpha (CHKα). Due to the metabolic instability of choline radiotracers and the increasing use of late-imagin
Externí odkaz:
https://doaj.org/article/74674289d27f44588c3184f2bea4b18b
Autor:
Martin J. Connor, Mesfin G. Genie, David Burns, Edward J. Bass, Michael Gonzalez, Naveed Sarwar, Alison Falconer, Stephen Mangar, Tim Dudderidge, Vincent Khoo, Mathias Winkler, Hashim U. Ahmed, Verity Watson
Publikováno v:
European Urology Open Science, Vol 36, Iss , Pp 9-18 (2022)
Context: Advances in systemic agents have increased overall survival for men diagnosed with metastatic prostate cancer. Additional cytoreductive prostate treatments and metastasis-directed therapies are under evaluation. These confer toxicity but may
Externí odkaz:
https://doaj.org/article/c5858afe4257417b8ca022687f6a4f2d
Autor:
Emily Day, A. Toby Prevost, Matthew R. Sydes, Deepika Reddy, Taimur T. Shah, Mathias Winkler, Tim Dudderidge, John Staffurth, Stuart McCracken, Vincent Khoo, Puja Jadav, Natalia Klimowska-Nassar, Thiagarajah Sasikaran, Hashim U. Ahmed, Francesca Fiorentino
Publikováno v:
Trials, Vol 22, Iss 1, Pp 1-12 (2021)
Abstract Background Randomised controlled trials (RCTs) for surgical interventions have often proven difficult with calls for innovative approaches. The Imperial Prostate (IP4) Comparative Health Research Outcomes of Novel Surgery in prostate cancer
Externí odkaz:
https://doaj.org/article/852ed8f3f23e4607b9359eacd6bd00ac
Autor:
Heba Alshaker, Ewan Hunter, Matthew Salter, Aroul Ramadass, Willem Westra, Mathias Winkler, Jayne Green, Alexandre Akoulitchev, Dmitri Pchejetski
Publikováno v:
Frontiers in Oncology, Vol 12 (2022)
BackgroundThree-dimensional chromosome loop conformations are powerful regulators of gene expression. These chromosome conformations can be detected both in tumour and in circulating cells and have significant disease biomarker potential. We have rec
Externí odkaz:
https://doaj.org/article/7a4c9e4f4d964364a0dae4675552a82c
Autor:
Heba Alshaker, Robert Mills, Ewan Hunter, Matthew Salter, Aroul Ramadass, Benjamin Matthew Skinner, Willem Westra, Jayne Green, Alexandre Akoulitchev, Mathias Winkler, Dmitri Pchejetski
Publikováno v:
Journal of Translational Medicine, Vol 19, Iss 1, Pp 1-14 (2021)
Abstract Background Current diagnostic blood tests for prostate cancer (PCa) are unreliable for the early stage disease, resulting in numerous unnecessary prostate biopsies in men with benign disease and false reassurance of negative biopsies in men
Externí odkaz:
https://doaj.org/article/9f539c2bf78148939ee7c393f2641eb1
Autor:
Dmitri Pchejetski, Ewan Hunter, Mehrnoush Dezfouli, Matthew Salter, Ryan Powell, Jayne Green, Tarun Naithani, Christina Koutsothanasi, Heba Alshaker, Jiten Jaipuria, Martin J. Connor, David Eldred-Evans, Francesca Fiorentino, Hashim Ahmed, Alexandre Akoulitchev, Mathias Winkler
Publikováno v:
Cancers, Vol 15, Iss 3, p 821 (2023)
Background: Prostate cancer (PCa) has a high lifetime prevalence (one out of six men), but currently there is no widely accepted screening programme. Widely used prostate specific antigen (PSA) test at cut-off of 3.0 ng/mL does not have sufficient ac
Externí odkaz:
https://doaj.org/article/b26011f34511475ab9a57ee6399a7dc3
Autor:
Martin John Connor, Johanna Sukumar, Naveed Sarwar, Michael Gonzalez, Alison Falconer, Natalia Klimowska-Nassar, Kamalram Thippu Jayaprakash, Dolan Basak, Gail Horan, Bhavan Rai, Stephen Mangar, Vincent Khoo, Tim Dudderidge, Mathias Winkler, Hashim Uddin Ahmed, Mesfin G Genie, Verity Watson, Tzveta Pokrovska, Feargus Hosking-Jervis, Angus Robinson, Mark Beresford
Publikováno v:
BMJ Open, Vol 11, Iss 11 (2021)
Externí odkaz:
https://doaj.org/article/a235c0be59294643acac82c308b7dc0a
Autor:
Marina Triquell, Lucas Regis, Mathias Winkler, Nicolás Valdés, Mercè Cuadras, Ana Celma, Jacques Planas, Juan Morote, Enrique Trilla
Publikováno v:
Cancers, Vol 14, Iss 16, p 3966 (2022)
The correct identification of extracapsular extension (ECE) of prostate cancer (PCa) on multiparametric magnetic resonance imaging (mpMRI) is crucial for surgeons in order to plan the nerve-sparing approach in radical prostatectomy. Nerve-sparing str
Externí odkaz:
https://doaj.org/article/06b4e4f63c91418faa64f90317ae49a7
Autor:
Francesca Fiorentino, Iqbal Shergill, Manal Kumar, Martin John Connor, Taimur Tariq Shah, Katarzyna Smigielska, Emily Day, Johanna Sukumar, Naveed Sarwar, Michael Gonzalez, Alison Falconer, Natalia Klimowska-Nassar, Martin Evans, Olivia Frances Naismith, Kamalram Thippu Jayaprakash, Derek Price, Shiva Gayadeen, Dolan Basak, Gail Horan, Denise Sheehan, Azman Ibrahim, Cathryn Brock, Rachel A. Pearson, Nicola Anyamene, Catherine Heath, Bhavan Rai, Giles Hellawell, Stuart McCracken, Bijan Khoubehi, Stephen Mangar, Vincent Khoo, Tim Dudderidge, John Nicholas Staffurth, Mathias Winkler, Hashim Uddin Ahmed
Publikováno v:
BMJ Open, Vol 11, Iss 2 (2021)
Introduction Survival in men diagnosed with de novo synchronous metastatic prostate cancer has increased following the use of upfront systemic treatment, using chemotherapy and other novel androgen receptor targeted agents, in addition to standard an
Externí odkaz:
https://doaj.org/article/5990ac2cc8ae4ff48516b35753c3f048
Autor:
Mathias Winkler, Magnus Aa. Gjennestad, Dick Bedeaux, Signe Kjelstrup, Raffaela Cabriolu, Alex Hansen
Publikováno v:
Frontiers in Physics, Vol 8 (2020)
We compute the fluid flow time correlation functions of incompressible, immiscible two-phase flow in porous media using a 2D network model. Given a properly chosen representative elementary volume, the flow rate distributions are Gaussian, and the in
Externí odkaz:
https://doaj.org/article/8785fa61de714514b6045f6641f5f3b6