Zobrazeno 1 - 10
of 14
pro vyhledávání: '"Mathias Wiemann"'
Autor:
Simon Birgersson, Johan Morrill, Olof Stenström, Mathias Wiemann, Ulrich Weininger, Pär Söderhjelm, Mikael Akke, Henrik Stålbrand
Publikováno v:
Catalysts, Vol 13, Iss 9, p 1281 (2023)
β-Mannanases hydrolyze β-mannans, important components of plant and microalgae cell walls. Retaining β-mannanases can also catalyze transglycosylation, forming new β-mannosidic bonds that are applicable for synthesis. This study focused on the bl
Externí odkaz:
https://doaj.org/article/6119ba8797c04ddcb3f1db048d4f1ae6
Autor:
Abhishek Bhattacharya, Lovisa Majtorp, Simon Birgersson, Mathias Wiemann, Krishnan Sreenivas, Phebe Verbrugghe, Olivier Van Aken, Ed W. J. Van Niel, Henrik Stålbrand
Publikováno v:
Microorganisms, Vol 10, Iss 12, p 2496 (2022)
β-Mannan is abundant in the human diet and in hemicellulose derived from softwood. Linear or galactose-substituted β-mannan-oligosaccharides (MOS/GMOSs) derived from β-mannan are considered emerging prebiotics that could stimulate health-associate
Externí odkaz:
https://doaj.org/article/4070b61648a9494183c5a24cc2b7cfb0
Publikováno v:
Applied Sciences, Vol 12, Iss 10, p 5123 (2022)
The transglycosylation behavior and capacity of two clan GH-D α-galactosidases, BoGal36A from the gut bacterium Bacteroides ovatus and Aga27A from the guar plant, was investigated and compared. The enzymes were screened for the ability to use para-n
Externí odkaz:
https://doaj.org/article/840fd31c927d410d8eedba7586617749
Autor:
Eva-Christina Ahlgren, Mostafa Fekry, Mathias Wiemann, Christopher A Söderberg, Katja Bernfur, Olex Gakh, Morten Rasmussen, Peter Højrup, Cecilia Emanuelsson, Grazia Isaya, Salam Al-Karadaghi
Publikováno v:
PLoS ONE, Vol 12, Iss 12, p e0188937 (2017)
Patients suffering from the progressive neurodegenerative disease Friedreich's ataxia have reduced expression levels of the protein frataxin. Three major isoforms of human frataxin have been identified, FXN42-210, FXN56-210 and FXN81-210, of which FX
Externí odkaz:
https://doaj.org/article/b6b16bcc6c0e436e8309d9dfeed6c48d
Autor:
Samuel J. Butler, Simon Birgersson, Mathias Wiemann, Monica Arcos-Hernandez, Henrik Stålbrand
Publikováno v:
Process Biochemistry. 112:154-166
Retaining β-mannanases are glycoside hydrolases (GHs) that can potentially be applied for synthesis of glycosides by catalysis of transglycosylation reactions. A novel active-site double mutant (R171 K/E205D) of the catalytic module (CM) of the fami
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::41e96980830eaffecc7fb301f5c77092
https://doi.org/10.1016/j.procbio.2021.11.028
https://doi.org/10.1016/j.procbio.2021.11.028
Publikováno v:
Applied Sciences; Volume 12; Issue 10; Pages: 5123
The transglycosylation behavior and capacity of two clan GH-D α-galactosidases, BoGal36A from the gut bacterium Bacteroides ovatus and Aga27A from the guar plant, was investigated and compared. The enzymes were screened for the ability to use para-n
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::67543c4f9b1d3bb38e5975b1591415bd
Autor:
Derek T. Logan, Mathias Wiemann, Viktoria Bågenholm, Anna Rosengren, Henrik Stålbrand, Abhishek Bhattacharya, Sumitha K. Reddy
Publikováno v:
'Journal of Biological Chemistry ', vol: 294, pages: 9100-9117 (2019)
The galactomannan utilization locus (BoManPUL) of the human gut bacterium Bacteroides ovatus encodes BoMan26B, a cell-surface–exposed endomannanase whose functional and structural features have been unclear. Our study now places BoMan26B in context
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::75f4e62d5fbe81a471d4e8e6729323fe
https://epn-library.esrf.fr/flora/jsp/index_view_direct_anonymous.jsp?record=doc:PUB_ESRF:52644
https://epn-library.esrf.fr/flora/jsp/index_view_direct_anonymous.jsp?record=doc:PUB_ESRF:52644
Autor:
Rossana Lupo, Eva Nordberg Karlsson, David Teze, Mette Errebo Rønne, Henrik Stålbrand, Jens Ø. Duus, Birgitte Zeuner, Birte Svensson, Régis Fauré, Mathias Wiemann, Jiao Zhao, Marlene Vuillemin, Göran Carlström, Yves-Henri Sanejouand, Zubaida Gulshan Kazi, Michael J. O’Donohue
Publikováno v:
Chemistry-A European Journal
Chemistry-A European Journal, In press, ⟨10.1002/chem.202100110⟩
Chemistry-A European Journal, Wiley-VCH Verlag, In press, ⟨10.1002/chem.202100110⟩
Teze, D, Zhao, J, Wiemann, M, Kazi, Z G A, Lupo, R, Zeuner, B, Vuillemin, M, Rønne, M E, Carlström, G, Duus, J Ø, Sanejouand, Y-H, O'Donohue, M J, Nordberg Karlsson, E, Fauré, R, Stålbrand, H & Svensson, B 2021, ' Rational Enzyme Design without Structural Knowledge: A Sequence-Based Approach for Efficient Generation of Transglycosylases ', Chemistry-A European Journal, vol. 27, no. 40, pp. 10323-10334 . https://doi.org/10.1002/chem.202100110
Chemistry-A European Journal, In press, ⟨10.1002/chem.202100110⟩
Chemistry-A European Journal, Wiley-VCH Verlag, In press, ⟨10.1002/chem.202100110⟩
Teze, D, Zhao, J, Wiemann, M, Kazi, Z G A, Lupo, R, Zeuner, B, Vuillemin, M, Rønne, M E, Carlström, G, Duus, J Ø, Sanejouand, Y-H, O'Donohue, M J, Nordberg Karlsson, E, Fauré, R, Stålbrand, H & Svensson, B 2021, ' Rational Enzyme Design without Structural Knowledge: A Sequence-Based Approach for Efficient Generation of Transglycosylases ', Chemistry-A European Journal, vol. 27, no. 40, pp. 10323-10334 . https://doi.org/10.1002/chem.202100110
International audience; Glycobiology is dogged by the relative scarcity of synthetic, defined oligosaccharides. Enzyme-catalysed glycosylation using glycoside hydrolases is feasible but is hampered by the innate hydrolytic activity of these enzymes.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f6f715607b890e69302d079c5337f20e
https://hal.inrae.fr/hal-02906907v2/document
https://hal.inrae.fr/hal-02906907v2/document
Autor:
Birte Svensson, Henrik Stålbrand, Eva Karlsson, Rossana Lupo, Jens Ø. Duus, David Teze, Régis Fauré, Yves-Henri Sanejouand, Zubaida Gulshan Kazi, Michael J. O’Donohue, Mathias Wiemann, Göran Carlström, Mette Errebo Rønne, Jiao Zhao
We present an enzyme engineering approach based solely on amino-acids sequence to convert glycoside hydrolases into transglycosylases. We demonstrate its effectiveness on enzymes form five different glycoside hydrolase families, synthesizing various
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::875dd48f81463ad4a598384aaf4111d0
https://doi.org/10.26434/chemrxiv.11538708.v2
https://doi.org/10.26434/chemrxiv.11538708.v2
Publikováno v:
LWT. 151:112215
Galactomannan (GM) in legumes and acetyl-galactoglucomannan (AcGGM) in softwoods are wide-spread β-mannans. Their depolymerisation is catalyzed by β-mannanases. We have investigated a cell-surface exposed and galactose-tolerant β-mannanase (BoMan2
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::67b1b2f38a5251ed13a1e125eb416bba
https://doi.org/10.1016/j.lwt.2021.112215
https://doi.org/10.1016/j.lwt.2021.112215