Zobrazeno 1 - 10
of 20
pro vyhledávání: '"Mathias Walther"'
Publikováno v:
International journal of pharmaceutics. 570
The aim of this study was to evaluate the influence of tableting process parameters, i.e. turret rotation speed, pre-compaction and main compaction pressures, and their interactions on layer adhesion of bilayer tablets. The elastic recovery after com
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e15b04344612ff010ffacf629ee3904d
https://pubmed.ncbi.nlm.nih.gov/31421200
https://pubmed.ncbi.nlm.nih.gov/31421200
Publikováno v:
AAPS PharmSciTech. 19(1)
The objective of this work was the preparation of osmotic tablets using polymer blends of cellulose acetate butyrate (CAB) or ethylcellulose with ammonio methacrylate copolymer (Eudragit® RL). The advantage of these coatings in comparison to the tra
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::29b0c2843b82512ca277f419dcdc2eee
https://pubmed.ncbi.nlm.nih.gov/28634790
https://pubmed.ncbi.nlm.nih.gov/28634790
Publikováno v:
International Journal of Pharmaceutics. 469:94-101
The objective of this study was to identify and evaluate key polymer properties affecting direct compression and drug release from water-insoluble matrices. Commonly used polymers, such as Kollidon(®) SR, Eudragit(®) RS and ethyl cellulose, were ch
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::293edab50e9a7b5b5f46a3de414df336
https://doi.org/10.1016/j.ijpharm.2014.04.033
https://doi.org/10.1016/j.ijpharm.2014.04.033
Autor:
Valerie Hoffart, Nantharat Pearnchob, Roland Bodmeier, Mathias Walther, Mesut Ciper, Martin Körber, Ross James Macrae
Publikováno v:
European Journal of Pharmaceutics and Biopharmaceutics. 78:447-454
Weakly basic drugs and their salts exhibit a decrease in aqueous solubility at higher pH, which can result in pH-dependent or even incomplete release of these drugs from extended release formulations. The objective of this study was to evaluate strat
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::426e07cebc94dc2b822a5f3d067f158c
https://doi.org/10.1016/j.ejpb.2011.03.018
https://doi.org/10.1016/j.ejpb.2011.03.018
Publikováno v:
Journal of Controlled Release. 125:1-15
The use of polymer blends as coating materials for controlled drug delivery systems can offer major advantages, including: (i) facilitated adjustment of desired drug release patterns, mechanical properties and drug release mechanisms, (ii) improved f
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::46daa108c2f0363a6f6256c396ee252c
https://doi.org/10.1016/j.jconrel.2007.09.012
https://doi.org/10.1016/j.jconrel.2007.09.012
Publikováno v:
Biomacromolecules. 6:2074-2083
The aim of this study was to coat theophylline-loaded spherical beads with pH-sensitive polymer blends to control the resulting drug release kinetics. Various mixtures of ethylcellulose (water-insoluble) and Eudragit L (methacrylic-acid-ethyl-acrylat
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7247aa7cb07852ecfcf4f61ce3819892
https://doi.org/10.1021/bm0500704
https://doi.org/10.1021/bm0500704
Publikováno v:
Journal of Controlled Release. 89:457-471
THE OBJECTIVES OF THIS STUDY WERE: (i). to use blends of gastrointestinal tract (GIT)-insoluble and enteric polymers (ethyl cellulose and Eudragit L) as coating materials for multiparticulate controlled release dosage forms; (ii). to investigate the
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c0e7cd9215b71acba88669d8881fe9c4
https://doi.org/10.1016/s0168-3659(03)00155-x
https://doi.org/10.1016/s0168-3659(03)00155-x
Publikováno v:
Journal of Pharmacy and Pharmacology. 52:903-909
We report the development of a chronopharmaceutical capsule drug delivery system capable of releasing drug after pre-determined time delays. The drug formulation is sealed inside the insoluble capsule body by an erodible tablet (ET). The release time
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::665c35dd4cf327d5b97b870ff41fd257
https://doi.org/10.1211/0022357001774787
https://doi.org/10.1211/0022357001774787
Autor:
Mathias Walther, Heino Finkelmann
Publikováno v:
Macromolecular Rapid Communications. 19:145-148
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::346b46afea808a7371a7c3e88c4f389d
https://doi.org/10.1002/(sici)1521-3927(19980301)19:3<145::aid-marc145>3.0.co
https://doi.org/10.1002/(sici)1521-3927(19980301)19:3<145::aid-marc145>3.0.co
Publikováno v:
Macromolecular Chemistry and Physics. 199:223-237
AB and ABA block copolymers are synthesized by direct living anionic polymerization where the A-block is a liquid crystalline side chain polymer (LC-block) and the B-block is an isotropic polymer (I-block). Similar to amphiphilic block copolymers wit
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::bc48b8d34b699dab4bd462c076e26ee1
https://doi.org/10.1002/(sici)1521-3935(19980201)199:2<223::aid-macp223>3.0.co
https://doi.org/10.1002/(sici)1521-3935(19980201)199:2<223::aid-macp223>3.0.co