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pro vyhledávání: '"Mathias Van Impe"'
Autor:
Julie de Backer, Violette de Leeuw, Mathias Van Impe, Marine Vanhomwegen, Gerlinde Logghe, Margie Oblinado, Marco Stampanoni, Patrick Segers, Laura Muino Mosquera, Lynn Sakai, Patrick Sips
Publikováno v:
Cardiovascular Research. 118
Introduction Marfan syndrome (MFS) is caused by a defect in fibrillin-1, which binds TGF-beta via interaction with latent TGF-beta binding proteins (LTBPs). The role of TGF-beta in MFS is controversial. Objectives use dedicated mouse models for MFS,