Zobrazeno 1 - 10
of 13
pro vyhledávání: '"Mathias Van Bulck"'
Autor:
Mireia Medrano, Wissal Allaoui, Mathias Van Bulck, Sofie Thys, Leila Makrini-Maleville, Eve Seuntjens, Winnok H. De Vos, Emmanuel Valjent, Bálazs Gaszner, Ann Van Eeckhaut, Ilse Smolders, Dimitri De Bundel
Publikováno v:
Open Biology, Vol 13, Iss 6 (2023)
Neuromedin U (NMU) is an evolutionary conserved neuropeptide that has been implicated in multiple processes, such as circadian regulation, energy homeostasis, reward processing and stress coping. Although the central expression of NMU has been addres
Externí odkaz:
https://doaj.org/article/26de393b757b43169dd0b8e8bb418d2a
Autor:
Lindsay Sprimont, Pauline Janssen, Kathleen De Swert, Mathias Van Bulck, Ilse Rooman, Jacques Gilloteaux, Ann Massie, Charles Nicaise
Publikováno v:
Scientific Reports, Vol 11, Iss 1, Pp 1-15 (2021)
Abstract xCT is the specific subunit of System xc-, an antiporter importing cystine while releasing glutamate. Although xCT expression has been found in the spinal cord, its expression and role after spinal cord injury (SCI) remain unknown. The aim o
Externí odkaz:
https://doaj.org/article/0c960f346c93467d92befefbdd905a9b
TNF-α-Secreting Lung Tumor-Infiltrated Monocytes Play a Pivotal Role During Anti-PD-L1 Immunotherapy
Autor:
Kirsten De Ridder, Hanne Locy, Elisa Piccioni, Miren Ibarra Zuazo, Robin Maximilian Awad, Stefaan Verhulst, Mathias Van Bulck, Yannick De Vlaeminck, Quentin Lecocq, Eva Reijmen, Wout De Mey, Lien De Beck, Thomas Ertveldt, Isabel Pintelon, Jean-Pierre Timmermans, David Escors, Marleen Keyaerts, Karine Breckpot, Cleo Goyvaerts
Publikováno v:
Frontiers in Immunology, Vol 13 (2022)
Immune checkpoint blockade (ICB) of the PD-1 pathway revolutionized the survival forecast for advanced non-small cell lung cancer (NSCLC). Yet, the majority of PD-L1+ NSCLC patients are refractory to anti-PD-L1 therapy. Recent observations indicate a
Externí odkaz:
https://doaj.org/article/8cb0f64de304414d9efd07fa0701e7a3
Autor:
Andreia V. Pinho, Mathias Van Bulck, Lorraine Chantrill, Mehreen Arshi, Tatyana Sklyarova, David Herrmann, Claire Vennin, David Gallego-Ortega, Amanda Mawson, Marc Giry-Laterriere, Astrid Magenau, Gunther Leuckx, Luc Baeyens, Anthony J. Gill, Phoebe Phillips, Paul Timpson, Andrew V. Biankin, Jianmin Wu, Ilse Rooman
Publikováno v:
Nature Communications, Vol 9, Iss 1, Pp 1-14 (2018)
SLIT-ROBO alterations arise in pancreatic ductal adenocarcinoma (PDAC), but their role in the pancreas is unclear. Here, the authors use mouse models to show that loss of epithelial Robo2 activates the neighbouring stroma via TGF-β signalling; findi
Externí odkaz:
https://doaj.org/article/7bcf752c0ac345e8b916a29cc45a9a4f
Autor:
Kirsten De Ridder, Hanne Locy, Elisa Piccioni, Miren Ibarra Zuazo, Robin Maximilian Awad, Stefaan Verhulst, Mathias Van Bulck, Yannick De Vlaeminck, Quentin Lecocq, Eva Reijmen, Wout De Mey, Lien De Beck, Thomas Ertveldt, Isabel Pintelon, Jean-Pierre Timmermans, David Escors, Marleen Keyaerts, Karine Breckpot, Cleo Goyvaerts
Publikováno v:
Frontiers in immunology
Academica-e. Repositorio Institucional de la Universidad Pública de Navarra
instname
Academica-e. Repositorio Institucional de la Universidad Pública de Navarra
instname
Immune checkpoint blockade (ICB) of the PD-1 pathway revolutionized the survival forecast for advanced non-small cell lung cancer (NSCLC). Yet, the majority of PD-L1+ NSCLC patients are refractory to anti-PD-L1 therapy. Recent observations indicate a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::637189a9817d5664fb7792a00077d19e
https://hdl.handle.net/2454/43383
https://hdl.handle.net/2454/43383
Autor:
David Gallego-Ortega, Paul Timpson, Tatyana Sklyarova, Amanda Mawson, Claire Vennin, Jianmin Wu, Anthony J. Gill, Gunther Leuckx, Mathias Van Bulck, Marc Giry-Laterriere, Ilse Rooman, Lorraine A. Chantrill, Andreia V. Pinho, Phoebe A. Phillips, Astrid Magenau, Mehreen Arshi, David Herrmann, Andrew V. Biankin, Luc Baeyens
Publikováno v:
Nature Communications, Vol 9, Iss 1, Pp 1-14 (2018)
Nature Communications
Nature Communications
Whereas genomic aberrations in the SLIT-ROBO pathway are frequent in pancreatic ductal adenocarcinoma (PDAC), their function in the pancreas is unclear. Here we report that in pancreatitis and PDAC mouse models, epithelial Robo2 expression is lost wh
Autor:
Pierre Lefesvre, Katarina Coolens, Farzad Esni, Nelson Dusetti, Harry Heimberg, Luc Bouwens, Jean-Luc Van Laethem, Yves Heremans, Gunter Leuckx, Patrick Jacquemin, Angel Fernandez Ruiz, Tatjana Arsenijevic, Meritxell Rovira, Christelle Bouchart, Peter In't Veld, Wim Waelput, Ilse Rooman, Sandrina Martens, Nicky D'Haene, Abdessamad El Kaoutari, Jaime Martinez de Villareal, Diedert Luc De Paep, Francisco X. Real, Joan Casamitjana, Hediel Madhloum, Mathias Van Bulck
Publikováno v:
Gut
Gut, BMJ Publishing Group, In press, ⟨10.1136/gutjnl-2020-322874⟩
Gut, In press, ⟨10.1136/gutjnl-2020-322874⟩
Gut, p. [1-13] (2021)
Gut, BMJ Publishing Group, In press, ⟨10.1136/gutjnl-2020-322874⟩
Gut, In press, ⟨10.1136/gutjnl-2020-322874⟩
Gut, p. [1-13] (2021)
Objective: The aggressive basal-like molecular subtype of pancreatic ductal adenocarcinoma (PDAC) harbours a ΔNp63 (p40) gene expression signature reminiscent of a basal cell type. Distinct from other epithelia with basal tumours, ΔNp63+ basal cell
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7b1753811ff45faa28755ff5c1e5e2cd
https://hal.archives-ouvertes.fr/hal-03314798/document
https://hal.archives-ouvertes.fr/hal-03314798/document
Autor:
Ann Massie, Jacques Gilloteaux, Lindsay Sprimont, Kathleen De Swert, Pauline Janssen, Charles Nicaise, Mathias Van Bulck, Ilse Rooman
Publikováno v:
Scientific Reports
Scientific Reports, Vol 11, Iss 1, Pp 1-15 (2021)
Sprimont, L, Janssen, P, De Swert, K, Van Bulck, M, Roman, I, GILLOTEAUX, J, Massie, A & Nicaise, C 2021, ' Cystine–glutamate antiporter deletion accelerates motor recovery and improves histological outcomes following spinal cord injury in mice ', Scientific Reports, vol. 11, no. 1, 12227 . https://doi.org/10.1038/s41598-021-91698-y
Scientific Reports, Vol 11, Iss 1, Pp 1-15 (2021)
Sprimont, L, Janssen, P, De Swert, K, Van Bulck, M, Roman, I, GILLOTEAUX, J, Massie, A & Nicaise, C 2021, ' Cystine–glutamate antiporter deletion accelerates motor recovery and improves histological outcomes following spinal cord injury in mice ', Scientific Reports, vol. 11, no. 1, 12227 . https://doi.org/10.1038/s41598-021-91698-y
xCT is the specific subunit of System xc-, an antiporter importing cystine while releasing glutamate. Although xCT expression has been found in the spinal cord, its expression and role after spinal cord injury (SCI) remain unknown. The aim of this st
Autor:
Ellis Michiels, Patrick Jacquemin, Ilse Rooman, Mineo Kurokawa, Yves Heremans, Diedert Luc De Paep, Isabelle Houbracken, Luc Bouwens, Jonathan Baldan, Susumu Goyama, Elyne Backx, Mathias Van Bulck, Elke Wauters
Publikováno v:
Cell death and differentiation, Vol. 28, no.9, p. 2601-2615 (2021)
Cell Death and Differentiation
Cell Death and Differentiation
Maintenance of the pancreatic acinar cell phenotype suppresses tumor formation. Hence, repetitive acute or chronic pancreatitis, stress conditions in which the acinar cells dedifferentiate, predispose for cancer formation in the pancreas. Dedifferent
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::bfdccca3d6f1cc065e71875c4bb08fcc
https://doi.org/10.1101/2020.08.21.260539
https://doi.org/10.1101/2020.08.21.260539
Autor:
Francisco X. Real, Sandrina Martens, Meritxell Rovira, Gunter Leuckx, Farzad Esni, Katarina Coolens, Harry Heimberg, Luc Bouwens, Pierre Lefesvre, Ilse Rooman, Patrick Jacquemin, Hediel Madhloum, Mathias Van Bulck, Peter In't Veld
SUMMARYObjectiveAn aggressive basal-like molecular subtype of pancreatic ductal adenocarcinoma (PDAC) exists, driven by ΔNp63. In other epithelia, ΔNp63+basal cells have stem cell capacity and can be at the origin of tumors. In the pancreas, basal
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6923c51a43372221e8c9d5c815aa2be5
https://doi.org/10.1101/2020.08.20.259317
https://doi.org/10.1101/2020.08.20.259317