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Restoration of the self-splicing activity of a defective group II intron by a small trans-acting RNA
Autor:
Mathias Suchy, Carlo Schmelzer
Publikováno v:
Journal of Molecular Biology. 222:179-187
The yeast mitochondrial group II intron bI1 is self-splicing in vitro. We have introduced a deletion of hairpin C1 within the structural domain 1 that abolishes catalytic activity of the intron in the normal splicing reaction in cis, but does less se