Zobrazeno 1 - 10
of 15
pro vyhledávání: '"Mathias S. Dick"'
Autor:
Lorenzo Sborgi, Johanna Ude, Mathias S. Dick, Jonathan Vesin, Marc Chambon, Gerardo Turcatti, Petr Broz, Sebastian Hiller
Publikováno v:
Cell Stress, Vol 2, Iss 4, Pp 82-90 (2018)
The protein ASC is a central component of most inflammasome complexes, forming functional oligomeric filaments that activate large amounts of pro-caspase-1 for further IL-1β processing and the induction of Gasdermin D-dependent cell death. The centr
Externí odkaz:
https://doaj.org/article/be174553d9cb403f94a5fd589b690b57
Autor:
Katharina S. Schneider, Christina J. Groß, Roland F. Dreier, Benedikt S. Saller, Ritu Mishra, Oliver Gorka, Rosalie Heilig, Etienne Meunier, Mathias S. Dick, Tamara Ćiković, Jan Sodenkamp, Guillaume Médard, Ronald Naumann, Jürgen Ruland, Bernhard Kuster, Petr Broz, Olaf Groß
Publikováno v:
Cell Reports, Vol 21, Iss 13, Pp 3846-3859 (2017)
Inflammasomes activate the protease caspase-1, which cleaves interleukin-1β and interleukin-18 to generate the mature cytokines and controls their secretion and a form of inflammatory cell death called pyroptosis. By generating mice expressing enzym
Externí odkaz:
https://doaj.org/article/caf0ef9e648d468094e235c5382d0983
Publikováno v:
Nature Communications, Vol 7, Iss 1, Pp 1-13 (2016)
Inflammasomes regulate IL-1β family maturation and pyroptosis. Here the authors show that ASC oligomerization and the formation of ASC specks are needed for IL-1β processing, but are not required for pyroptosis, indicating distinct inflammasome reg
Externí odkaz:
https://doaj.org/article/846a5b7a13d34863b94bbdb0151a87c3
Publikováno v:
Nature Communications, Vol 8, Iss 1, Pp 1-1 (2017)
Nature Communications 7: Article number: 11929 (2016); Published 22 June 2016; Updated 17 March 2017 In this Article, residues D128 and D132 of ASC are consistently referred to incorrectly as D130 and D134, respectively. These errors appear in the Re
Externí odkaz:
https://doaj.org/article/9168b647d0b145eaa184de4b65fd7722
Autor:
Marc Chambon, Lorenzo Sborgi, Petr Broz, Gerardo Turcatti, Johanna Ude, Sebastian Hiller, Mathias S. Dick, Johnathan Vesin
Publikováno v:
Cell Stress, Vol 2, Iss 4, Pp 82-90 (2018)
Cell Stress
Cell Stress, vol. 2, no. 4, pp. 82-90
Cell Stress
Cell Stress, vol. 2, no. 4, pp. 82-90
The protein ASC is a central component of most inflammasome complexes, forming functional oligomeric filaments that activate large amounts of pro-caspase-1 for further IL-1β processing and the induction of Gasdermin D-dependent cell death. The centr
Autor:
Petr Broz, Etienne Meunier, Lorenzo Sborgi, Rosalie Heilig, Sebastian Hiller, Mathias S. Dick
Publikováno v:
European Journal of Immunology. 48:584-592
The pro-inflammatory cytokine IL-1β is well known for its role in host defense and the initiation of potent inflammatory responses. It is processed from its inactive pro-form by the inflammatory caspase-1 into its mature bioactive form, which is the
Autor:
Roland F. Dreier, Ritu Mishra, Jürgen Ruland, Katharina S. Schneider, Tamara Cikovic, Jan Sodenkamp, Oliver Gorka, Ronald Naumann, Rosalie Heilig, Mathias S. Dick, Petr Broz, Etienne Meunier, Benedikt S. Saller, Christina J. Groß, Bernhard Kuster, Olaf Groß, Guillaume Médard
Publikováno v:
Cell Reports, Vol 21, Iss 13, Pp 3846-3859 (2017)
Cell Reports
Cell reports, vol. 21, no. 13, pp. 3846-3859
Cell Reports
Cell reports, vol. 21, no. 13, pp. 3846-3859
Summary Inflammasomes activate the protease caspase-1, which cleaves interleukin-1β and interleukin-18 to generate the mature cytokines and controls their secretion and a form of inflammatory cell death called pyroptosis. By generating mice expressi
Autor:
Thomas Henry, José Carlos Santos, Mathias S. Dick, Petr Broz, Masahiro Yamamoto, Klaus Pfeffer, Daniel Degrandi, Pawel Pelczar, Brice Lagrange, Etienne Meunier
Publikováno v:
EMBO Journal
EMBO Journal, 2018, 37 (6), ⟨10.15252/embj.201798089⟩
EMBO Journal, EMBO Press, 2018, 37 (6), ⟨10.15252/embj.201798089⟩
EMBO Journal, 2018, 37 (6), ⟨10.15252/embj.201798089⟩
EMBO Journal, EMBO Press, 2018, 37 (6), ⟨10.15252/embj.201798089⟩
International audience; Pathogenic and commensal Gram-negative bacteria produce and release outer membrane vesicles (OMVs), which present several surface antigens and play an important role for bacterial pathogenesis. OMVs also modulate the host immu
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::01f23ad2885de4e218de70b22f183255
https://hal.science/hal-01911461
https://hal.science/hal-01911461
Autor:
Adam Mazur, Francesco Ravotti, Lorenzo Sborgi, Henning Stahlberg, Anja Böckmann, Sina Reckel, Mohamed Chami, Sebastian Hiller, Matthias Huber, Mathias S. Dick, Petr Broz, Sebastian Scherer, Edward H. Egelman, Beat H. Meier, Venkata P. Dandey
Publikováno v:
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
Inflammasomes are multiprotein complexes that control the innate immune response by activating caspase-1, thus promoting the secretion of cytokines in response to invading pathogens and endogenous triggers. Assembly of inflammasomes is induced by act
Autor:
Mathias S. Dick, Mélanie Rigard, Sébastien Dussurgey, Klaus Pfeffer, Anne Kistner, Roland F. Dreier, Leonie Anton, Pierre Wallet, Masahiro Yamamoto, Stéphanie Costanzo, Etienne Meunier, Sebastian Rühl, Daniel Degrandi, Petr Broz, Thomas Henry
Publikováno v:
Nature Immunology
Nature Immunology, Nature Publishing Group, 2015, 16 (5), pp.476-484. ⟨10.1038/ni.3119⟩
Nature Immunology, 2015, 16 (5), pp.476-484. ⟨10.1038/ni.3119⟩
NATURE IMMUNOLOGY
Nature immunology
Nature Immunology, Nature Publishing Group, 2015, 16 (5), pp.476-484. ⟨10.1038/ni.3119⟩
Nature Immunology, 2015, 16 (5), pp.476-484. ⟨10.1038/ni.3119⟩
NATURE IMMUNOLOGY
Nature immunology
The AIM2 inflammasome detects double-stranded DNA in the cytosol and induces caspase-1-dependent pyroptosis as well as release of the inflammatory cytokines interleukin 1β (IL-1β) and IL-18. AIM2 is critical for host defense against DNA viruses and