Zobrazeno 1 - 10
of 17
pro vyhledávání: '"Mathias Pawlak"'
Autor:
Audrey M Hendley, Arjun A Rao, Laura Leonhardt, Sudipta Ashe, Jennifer A Smith, Simone Giacometti, Xianlu L Peng, Honglin Jiang, David I Berrios, Mathias Pawlak, Lucia Y Li, Jonghyun Lee, Eric A Collisson, Mark S Anderson, Gabriela K Fragiadakis, Jen Jen Yeh, Chun Jimmie Ye, Grace E Kim, Valerie M Weaver, Matthias Hebrok
Publikováno v:
eLife, Vol 10 (2021)
To study disease development, an inventory of an organ's cell types and understanding of physiologic function is paramount. Here, we performed single-cell RNA-sequencing to examine heterogeneity of murine pancreatic duct cells, pancreatobiliary cells
Externí odkaz:
https://doaj.org/article/62699ea62af1409c840ff2fb6ef43383
Autor:
Gerd Meyer zu Horste, Chuan Wu, Chao Wang, Le Cong, Mathias Pawlak, Youjin Lee, Wassim Elyaman, Sheng Xiao, Aviv Regev, Vijay K. Kuchroo
Publikováno v:
Cell Reports, Vol 16, Iss 2, Pp 392-404 (2016)
Interleukin-17 (IL-17)-producing helper T cells (Th17 cells) play an important role in autoimmune diseases. However, not all Th17 cells induce tissue inflammation or autoimmunity. Th17 cells require IL-23 receptor (IL-23R) signaling to become pathoge
Externí odkaz:
https://doaj.org/article/ad750fdbe8294565aafe901b7d5389df
Autor:
Lijun Qi, Michael Iskols, David Shi, Pranav Reddy, Christopher Walker, Karina Lezgiyeva, Tiphaine Voisin, Mathias Pawlak, Vijay K. Kuchroo, Isaac Chiu, David D. Ginty, Nikhil Sharma
Publikováno v:
bioRxiv
SummaryMechanical and thermal stimuli acting on the skin are detected by morphologically and physiologically distinct sensory neurons of the dorsal root ganglia (DRG). Achieving a holistic view of how this diverse neuronal population relays sensory i
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d96f3a446462a0077e882a2d9246a416
https://doi.org/10.1101/2023.04.22.537932
https://doi.org/10.1101/2023.04.22.537932
Autor:
Chun Jimmie Ye, David I. Berrios, Simone Giacometti, Matthias Hebrok, Arjun A. Rao, Honglin Jiang, Valerie M. Weaver, Jonghyun Lee, Mark S. Anderson, Sudipta Ashe, Xianlu L. Peng, Laura Leonhardt, Eric A. Collisson, Jen Jen Yeh, Gabriela K. Fragiadakis, Audrey M. Hendley, Jennifer A Smith, Lucia Y Li, Grace E. Kim, Mathias Pawlak
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::8ba470c26c3d05b24ce9e6e132086240
https://doi.org/10.7554/elife.67776.sa2
https://doi.org/10.7554/elife.67776.sa2
Autor:
David DeTomaso, Yvonne C. Lee, Ana C. Anderson, Vijay K. Kuchroo, Nir Yosef, Patrick R. Burkett, Danielle Dionne, Antonia Wallrapp, Meyer zu Horste G, Aviv Regev, Ramnik J. Xavier, Jackson Nyman, Chao Wang, Mathias Pawlak, Samantha J. Riesenfeld
SummaryThe cytokine receptor IL-23R plays a fundamental role in inflammation and autoimmunity. However, several observations have been difficult to reconcile under the assumption that only Th17 cells critically depend on IL-23 to acquire a pathogenic
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::fc05cb90675c3d4c9d0f53a8647add49
https://doi.org/10.1101/2021.01.24.426445
https://doi.org/10.1101/2021.01.24.426445
Publikováno v:
Curr Opin Immunol
CD4
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::ffe04c915d5e81570a2be20edb672e8c
https://pubmed.ncbi.nlm.nih.gov/33039897
https://pubmed.ncbi.nlm.nih.gov/33039897
Autor:
Thomas Seidenbecher, Sandra Martín-Salamanca, Jan-Kolja Strecker, Xiaolin Li, Jens Minnerup, Arthur Liesz, Michael Heming, Christian Thomas, Sven G. Meuth, Maike Hartlehnert, Anna-Lena Börsch, I-Na Lu, Alessio Ricci, Andrés Hidalgo, David Schafflick, Mathias Pawlak, Jolien Wolbert, Heinz Wiendl, Gerd Meyer zu Hörste
Publikováno v:
Nature neuroscience. 24(9)
The CNS is ensheathed by the meninges and cerebrospinal fluid, and recent findings suggest that these CNS-associated border tissues have complex immunological functions. Unlike myeloid lineage cells, lymphocytes in border compartments have yet to be
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7dba00555667e2c9772d15c9a6330c09
https://pubmed.ncbi.nlm.nih.gov/34253922
https://pubmed.ncbi.nlm.nih.gov/34253922
Autor:
Jakub Abramson, S. Sohail Ahmed, Marco A. Alba, Youssif M. Ali, Julian L. Ambrus, Agnes Andersson Svärd, Martin Aringer, Shervin Assassi, Thanda Aung, Ilya Ayzenberg, Robert N. Barker, Alan G. Baxter, Corrado Betterle, Stanca A. Birlea, Niklas K. Björkström, Paul A. Blair, Stephan Blüml, Xavier Bosch, Robert A. Brodsky, Yenan T. Bryceson, Patrick R. Burkett, James B. Bussel, Roberto Caricchio, Livia Casciola-Rosen, Patrizio Caturegli, Benjamin Chaigne-Delalande, Paulina Chalan, Lucienne Chatenoud, Philip L. Cohen, Megan A. Cooper, Ken Coppieters, Ronald G. Crystal, Donna A. Culton, Valentina Damato, Anne Davidson, Lorenzo Delfino, Peter J. Delves, Giulia Di Dalmazi, Betty Diamond, Luis A. Diaz, Ronald J. Falk, Marvin J. Fritzler, Stefania Gallucci, Sapna Gangaputra, Brian Gelbman, M. Eric Gershwin, Igal Gery, Daniel R. Getts, Ralf Gold, Yael Goldfarb, Jing Gong, Siamon Gordon, Jörg J. Goronzy, Judith M. Greer, Vanesa A. Guazzone, Luiza Guilherme, David A. Hafler, Bevra H. Hahn, Abdel Rahim A. Hamad, Hideaki Hamano, Leonard C. Harrison, Dirk Homann, Eystein S. Husebye, J. Charles Jennette, Richard J. Jones, Margaret A. Jordan, Jorge Kalil, Shigeyuki Kawa, Ziya Kaya, Christian W. Keller, Nicholas J.C. King, Maleewan Kitcharoensakkul, Kendo Kiyosawa, Christoph Königs, Mitchell Kronenberg, Vijay K. Kuchroo, Arian Laurence, Eun-Ju Lee, Helmar C. Lehmann, Åke Lernmark, Ida Lindbladh, Zhi Liu, Hans-Gustaf Ljunggren, Claudio Lunardi, Knut E.A. Lundin, Jan D. Lünemann, Michael P.T. Lunn, Livia Lustig, Charles R. Mackay, Ian R. Mackay, Clara Malattia, Luisa Martinez-Pomares, Alberto Martini, Claudia Mauri, Pamela A. McCombe, Fritz Melchers, Giorgina Mieli-Vergani, Frederick W. Miller, Stephen D. Miller, Masayuki Mizui, Jenny Mjösberg, Christian Münz, Jagtar Singh Nijjar, David A. Norris, Kristine Oleinika, Joost J. Oppenheim, Mathias Pawlak, Cristina Peligero-Cruz, Anneli Peters, Pärt Peterson, Kalliopi Pitarokoili, Fabio Presotto, Antonio Puccetti, Hamid Rabb, Patricia Raczek, M. Jubayer Rahman, Manuel Ramos-Casals, Noel R. Rose, Antony Rosen, Mohanraj Sadasivam, Adam Schiffenbauer, Wilhelm J. Schwaeble, H. Nida Sen, Marc Serota, Kazim A. Sheikh, Yehuda Shoenfeld, Ora Shovman, Joachim Sieper, Arthur M. Silverstein, Robert B. Sim, Kenneth G C Smith, Josef S. Smolen, Ludvig M. Sollid, Alanna Spiteri, Lawrence Steinman, John H. Stone, Uta Syrbe, Ami Tamhaney, Atsushi Tanaka, Veena Taneja, Kristin V. Tarbell, Elisa Tinazzi, Benedict K. Tiong, Ban-Hock Toh, George C. Tsokos, Kenneth S.K. Tung, John Varga, Diego Vergani, Mark A. Vickers, Stuart Viegas, Angela Vincent, Matthias von Herrath, Anthony P. Weetman, Joel V. Weinstock, John M. Wentworth, Sarah Wesley, Cornelia M. Weyand, Gerhard Wingender, Michael W. Winter, Renato Zanchetta, Moncef Zouali
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::7089e3cc62afc3d1808e8be1b4adbc79
https://doi.org/10.1016/b978-0-12-812102-3.00078-6
https://doi.org/10.1016/b978-0-12-812102-3.00078-6
Autor:
Alexandra Schnell, Linglin Huang, Meromit Singer, Anvita Singaraju, Rocky M. Barilla, Brianna M.L. Regan, Alina Bollhagen, Pratiksha I. Thakore, Danielle Dionne, Toni M. Delorey, Mathias Pawlak, Gerd Meyer zu Horste, Orit Rozenblatt-Rosen, Rafael A. Irizarry, Aviv Regev, Vijay K. Kuchroo
Publikováno v:
Cell
While intestinal Th17 cells are critical for maintaining tissue homeostasis, recent studies have implicated their roles in the development of extra-intestinal autoimmune diseases including multiple sclerosis. However, the mechanisms by which tissue T
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c1f10ce004e8bf90f96a70dd20b6c6a9
https://doi.org/10.1016/j.cell.2021.11.018
https://doi.org/10.1016/j.cell.2021.11.018
Autor:
Mathias Pawlak, Maike Hartlehnert, Tim Hagenacker, David Kindermann, M. Schäfers, Bernd C. Kieseier, Gerd Meyer zu Hörste, Angelika Derksen
Publikováno v:
Scientific Reports, Vol 7, Iss 1, Pp 1-10 (2017)
Scientific Reports
Scientific Reports
The activation of T helper cells requires antigens to be exposed on the surface of antigen presenting cells (APCs) via MHC class II (MHC-II) molecules. Expression of MHC-II is generally limited to professional APCs, but other cell types can express M
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d1fbe4c344d852b3dc9bad9b237b85ee
http://link.springer.com/article/10.1038/s41598-017-12744-2
http://link.springer.com/article/10.1038/s41598-017-12744-2