Výsledky vyhledávání - "Mathias Oertli"

Helicobacter pyloritargets dendritic cells to induce immune tolerance, promote persistence and confer protection against allergic asthma

Autor: Mathias Oertli, Anne Müller

Publikováno v: Gut microbes
Gut Microbes

The bacterial pathogen Helicobacter pylori is predominantly known for its tight association with peptic ulcer disease and gastric cancer. However recent evidence suggests that chronic infection with H. pylori may also be beneficial to the host by con

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7e2c579e1335724457504e75de56cf24
https://doi.org/10.4161/gmic.21750

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Helicobacter pylori gamma-glutamyl transpeptidase and vacuolating cytotoxin promote gastric persistence and immune tolerance

Autor: Joachim Maxeiner, Mathias Oertli, Anne Müller, Raphaela P. Semper, Manuel Noben, Markus Gerhard, Daniela B. Engler, Christian Taube, Sebastian Reuter

Publikováno v: Proceedings of the National Academy of Sciences, 110(8), 3047-3052
Proc Natl Acad Sci U S A.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Infection with the gastric bacterial pathogen Helicobacter pylori is typically contracted in early childhood and often persists for decades. The immunomodulatory properties of H. pylori that allow it to colonize humans persistently are believed to al

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7938d68376b4e96f758d28b03b6cd377
https://hdl.handle.net/1887/102258

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MicroRNA-155 is essential for the T cell-mediated control of Helicobacter pylori infection and for the induction of chronic Gastritis and Colitis

Autor: Manuel Koch, Mathias Oertli, Anne Müller, Thomas F. Meyer, Daniela B. Engler, Esther Kohler

Publikováno v: Journal of Immunology

MicroRNAs govern immune responses to infectious agents, allergens, and autoantigens and function by posttranscriptional repression of their target genes. In this paper, we have addressed the role of microRNA-155 (miR-155) in the control of Helicobact

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b1ea338ef64db563bd844df5bc93296d
https://pubmed.ncbi.nlm.nih.gov/21880981

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The C-terminally encoded, MHC class II-restricted T cell antigenicity of the helicobacter pylori virulence factor CagA promotes gastric preneoplasia

Autor: Anne Müller, Else Marie Agger, Iris Hitzler, Daniela B. Engler, Mathias Oertli, Isabelle C. Arnold

Publikováno v: Journal of immunology (Baltimore Md. : 1950)

Chronic infection with the human bacterial pathogen Helicobacter pylori causes gastritis and predisposes carriers to an increased gastric cancer risk. Consequently, H. pylori-specific vaccination is widely viewed as a promising strategy of gastric ca

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::746d19bd95329c5edeaa78030284d1a1
https://www.zora.uzh.ch/id/eprint/48046/

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Dendritic cells prevent rather than promote immunity conferred by a helicobacter vaccine using a mycobacterial adjuvant

Autor: Mathias Oertli, Burkhard Becher, Anne Müller, Else Marie Agger, Iris Hitzler

Publikováno v: Gastroenterology

Background & Aims Immunization against the gastric bacterium Helicobacter pylori could prevent many gastric cancers and other disorders. Most vaccination protocols used in preclinical models are not suitable for humans. New adjuvants and a better und

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9ff180b4ece93df74bf1f693f77620f9
https://www.zora.uzh.ch/id/eprint/48248/

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H. pylori exploits and manipulates innate and adaptive immune cell signaling pathways to establish persistent infection

Autor: Anne Müller, Mathias Oertli, Isabelle C. Arnold

Publikováno v: Cell communication and signaling : CCS
Cell Communication and Signaling : CCS
Cell Communication and Signaling, Vol 9, Iss 1, p 25 (2011)

Persistent infection with the gastric bacterial pathogen Helicobacter pylori causes gastritis and predisposes carriers to a high gastric cancer risk, but has also been linked to protection from allergic, chronic inflammatory and autoimmune diseases.

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::273bc5e53512ed914bdb94ee6de63c70
https://doi.org/10.1186/1478-811x-9-25

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