Zobrazeno 1 - 10
of 100
pro vyhledávání: '"Mathias Mericskay"'
Autor:
Wissam Mekary, Souha Fares, Farah Abdulhai, Gaelle Massoud, Marwan Refaat, Mathias Mericskay, George W. Booz, Fouad A. Zouein
Publikováno v:
Heliyon, Vol 9, Iss 9, Pp e19373- (2023)
Background: Patients with heart failure were affected severely by COVID-19. Most heart failure patients are on guideline directed medical therapy, which includes ACE inhibitors (ACEI) and ARBs. These medications were controversial at the beginning of
Externí odkaz:
https://doaj.org/article/789d028b1d4049598def7dc60fc1b0f3
Autor:
Nada J. Habeichi, Ghadir Amin, Bachir Lakkis, Rayane Kataya, Mathias Mericskay, George W. Booz, Fouad A. Zouein
Publikováno v:
Frontiers in Bioscience-Landmark, Vol 29, Iss 1, p 8 (2024)
Kidney damage in severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) can occur even in patients with no underlying kidney disease. Signs of kidney problems can progress to a state that demands dialysis and hampering recovery. Although not wi
Externí odkaz:
https://doaj.org/article/b91e1599eb974a9c986fcaed4eb163c8
Autor:
Anne Garnier, Jérôme Leroy, Claudine Deloménie, Philippe Mateo, Benoit Viollet, Vladimir Veksler, Mathias Mericskay, Renée Ventura-Clapier, Jérôme Piquereau
Publikováno v:
PLoS ONE, Vol 18, Iss 9, p e0292015 (2023)
The beta-adrenergic system is a potent stimulus for enhancing cardiac output that may become deleterious when energy metabolism is compromised as in heart failure. We thus examined whether the AMP-activated protein kinase (AMPK) that is activated in
Externí odkaz:
https://doaj.org/article/ac04777b61eb411db0fec894cce101ae
Autor:
Lucile Grimbert, Maria-Nieves Sanz, Mélanie Gressette, Catherine Rucker-Martin, Marta Novotova, Audrey Solgadi, Ahmed Karoui, Susana Gomez, Kaveen Bedouet, Eric Jacquet, Christophe Lemaire, Vladimir Veksler, Mathias Mericskay, Renée Ventura-Clapier, Jérôme Piquereau, Anne Garnier
Publikováno v:
Biology of Sex Differences, Vol 12, Iss 1, Pp 1-24 (2021)
Highlights AMPK is a metabolic sensor of cellular energy which regulates energy homeostasis. We generated a cardiac-specific inducible deletion of Ampkα2 and demonstrated that this deletion induces mild cardiac dysfunction in male only. Cardiac dysf
Externí odkaz:
https://doaj.org/article/81438108d8ef4b59a82a8ad86e49fea4
Autor:
Henver S. Brunetta, Heather L. Petrick, Iman Momken, Rachel M. Handy, Christopher Pignanelli, Everson A. Nunes, Jérôme Piquereau, Mathias Mericskay, Graham P. Holloway
Publikováno v:
Redox Biology, Vol 52, Iss , Pp 102307- (2022)
Dietary nitrate supplementation, and the subsequent serial reduction to nitric oxide, has been shown to improve glucose homeostasis in several pre-clinical models of obesity and insulin resistance. While the mechanisms remain poorly defined, the bene
Externí odkaz:
https://doaj.org/article/d7f353203b6342ebaecd6a19183f6092
Autor:
Antoine deZélicourt, Abdallah Fayssoil, Mbarka Dakouane‐Giudicelli, Isley De Jesus, Ahmed Karoui, Faouzi Zarrouki, Florence Lefebvre, Arnaud Mansart, Jean‐Marie Launay, Jerome Piquereau, Mariana G Tarragó, Marcel Bonay, Anne Forand, Sophie Moog, France Piétri‐Rouxel, Elise Brisebard, Claudia C S Chini, Sonu Kashyap, Matthew J Fogarty, Gary C Sieck, Mathias Mericskay, Eduardo N Chini, Ana Maria Gomez, José‐Manuel Cancela, Sabine de laPorte
Publikováno v:
EMBO Molecular Medicine, Vol 14, Iss 5, Pp n/a-n/a (2022)
Abstract Duchenne muscular dystrophy (DMD) is characterized by progressive muscle degeneration. Two important deleterious features are a Ca2+ dysregulation linked to Ca2+ influxes associated with ryanodine receptor hyperactivation, and a muscular nic
Externí odkaz:
https://doaj.org/article/ff8aa5831114408f802cc62d7a45fce4
Publikováno v:
International Journal of Molecular Sciences, Vol 23, Iss 13, p 7394 (2022)
Myocardin-related transcription factors (MRTFs) play a central role in the regulation of actin expression and cytoskeletal dynamics that are controlled by Rho GTPases. SRF is a ubiquitous transcription factor strongly expressed in muscular tissues. T
Externí odkaz:
https://doaj.org/article/5d4849065bcf4ffa838a32e78b65b5bf
Autor:
Kévin Monceaux, Mélanie Gressette, Ahmed Karoui, Julie Pires Da Silva, Jérôme Piquereau, Renée Ventura-Clapier, Anne Garnier, Mathias Mericskay, Christophe Lemaire
Publikováno v:
International Journal of Molecular Sciences, Vol 23, Iss 12, p 6628 (2022)
Disturbances in Endoplasmic Reticulum (ER) homeostasis induce ER stress, which has been involved in the development and progression of various heart diseases, including arrhythmias, cardiac hypertrophy, ischemic heart diseases, dilated cardiomyopathy
Externí odkaz:
https://doaj.org/article/200a60355617416fb55f3cf330a6bf92
Autor:
Ludovic Gaut, Marie-Ange Bonnin, Cédrine Blavet, Isabelle Cacciapuoti, Monika Orpel, Mathias Mericskay, Delphine Duprez
Publikováno v:
Biology Open, Vol 9, Iss 2 (2020)
One of the main challenges relating to tendons is to understand the regulators of the tendon differentiation program. The optimum culture conditions that favor tendon cell differentiation have not been identified. Mesenchymal stem cells present the a
Externí odkaz:
https://doaj.org/article/a0be48970cc74cdcb462eb4dfa96ebcb
Publikováno v:
International Journal of Molecular Sciences, Vol 23, Iss 1, p 30 (2021)
Heart failure (HF) is a plague of the aging population in industrialized countries that continues to cause many deaths despite intensive research into more effective treatments. Although the therapeutic arsenal to face heart failure has been expandin
Externí odkaz:
https://doaj.org/article/83b1ab95ed604ae19bafee657255a681