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pro vyhledávání: '"Mathias Mangion"'
Publikováno v:
Molecular Biotechnology. 64:278-292
Over-expression of the vesicular stomatitis virus glycoprotein (VSVG) in mammalian cells can induce the formation of VSVG-pseudotyped vesicles (named “gesicles”) from membrane budding. Its use as a nucleic acid delivery tool is still poorly docum
Autor:
Amine Kamen, Gary P. Kobinger, Anahita Bakhshizadeh Gashti, Mathias Mangion, Hiva Azizi, Sascha Kiesslich, Rénald Gilbert, Parminder S. Chahal, Jean-François Gélinas, Nasha Nassoury, Bruno Gaillet, Alain Garnier
Publikováno v:
Vaccine. 38(50)
Acquired Immune Deficiency Syndrome (AIDS) in humans is a result of the destruction of the immune system caused by Human Immunodeficiency Virus (HIV) infection. This serious epidemic is still progressing world-wide. Despite advances in treatment, a s
Introduction: Delivery of nucleic acid-based molecules in human cells is a highly studied approach for the treatment of several disorders including monogenic diseases and cancers. Non-viral vectors for DNA and RNA transfer, although in general less e
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e090997629ee4866d33613975e1e169b
Publikováno v:
Molecular Therapy. 24:S136-S137
Gene delivery methods are essential to understand fundamental cellular mechanisms and to develop new therapies. Recombinant viruses are efficient to transfer nucleic acids but their safety is a concern. In addition, some commercial transfection reage
Publikováno v:
Expert opinion on biological therapy. 13(7)
Introduction: Lentiviruses are a very potent class of viral vectors for which there is presently a rapidly growing interest for a number of gene therapy. However, their construction, production and purification need to be performed according to state