Zobrazeno 1 - 5
of 5
pro vyhledávání: '"Mathias Lichtenheld"'
Autor:
Tadeu Ambros, Abdel-Aziz Zidan, Maria Pallin, Alberto Montero, Mathias Lichtenheld, Marcela Díaz-Montero
Publikováno v:
The Journal of Immunology. 188:126.28-126.28
The impact of T cell receptor (TCR) affinity during homeostatic proliferation has been demonstrated using naive CD8+ T cells with high and low affinity TCR derived from different precursors. In this study, we investigated the impact of TCR affinity u
Publikováno v:
The Journal of Immunology. 188:44.26-44.26
Background: Chronic HIV infection is characterized by systemic immune activation (IA), accumulation of T cells with a skewed terminally-differentiated profile and a progressive loss of IL-21 production. Experiments described below address the hypothe
Publikováno v:
The Journal of Immunology. 184:42.15-42.15
Background: Chronic HIV infection is marked by defective cytotoxic T cell (CTL) effector function, skewed terminally-differentiated profile, and reduced expression of the costimulatory molecules CD27 and CD28. Incubation ex vivo of CTL from HIV infec
Publikováno v:
The Journal of Immunology. 178:S118-S118
Murine neonatal immune responses are commonly Th2 biased, characterized by rapid and high level Th2 cytokine production. These Th2-biased responses entail cell-intrinsic properties whose molecular basis is now beginning to become unveiled. We have re
Publikováno v:
Annals of the New York Academy of Sciences. 532:292-302
Cognate T cell-mediated functions require antigen and MHC-restricted recognition of target cells. T-effector functions comprise the delivery of signals for help, for suppression, or for cell death of the target cell. In the case of the delivery of cy