Zobrazeno 1 - 10
of 10
pro vyhledávání: '"Mathias Kaas"'
Autor:
Angela Pärn, Ditte Olsen, Jürgen Tuvikene, Mathias Kaas, Ekaterina Borisova, Mesut Bilgin, Mie Elhauge, Joachim Vilstrup, Peder Madsen, Mateusz C. Ambrozkiewicz, Roman U. Goz, Tõnis Timmusk, Victor Tarabykin, Camilla Gustafsen, Simon Glerup
Publikováno v:
Frontiers in Molecular Neuroscience, Vol 15 (2023)
PCSK9 induces lysosomal degradation of the low-density lipoprotein (LDL) receptor (LDLR) in the liver, hereby preventing removal of LDL cholesterol from the circulation. Accordingly, PCSK9 inhibitory antibodies and siRNA potently reduce LDL cholester
Externí odkaz:
https://doaj.org/article/0dab2a5c70df4751af18ae27826dc208
Autor:
Ditte Olsen, Niels Wellner, Mathias Kaas, Inge E. M. de Jong, Florence Sotty, Michael Didriksen, Simon Glerup, Anders Nykjaer
Publikováno v:
Translational Psychiatry, Vol 11, Iss 1, Pp 1-14 (2021)
Abstract Attention deficit hyperactivity disorder (ADHD) is the most frequently diagnosed neurodevelopmental disorder worldwide. Affected individuals present with hyperactivity, inattention, and cognitive deficits and display a characteristic paradox
Externí odkaz:
https://doaj.org/article/92593cd7cc714224b571f4954375bcbe
Autor:
Ditte Olsen, Mathias Kaas, Jesper Lundhede, Simon Molgaard, Anders Nykjær, Mads Kjolby, Søren D. Østergaard, Simon Glerup
Publikováno v:
Frontiers in Pharmacology, Vol 10 (2019)
Alcohol use disorder (AUD) is characterized by repetitive and uncontrolled intake of alcohol with severe consequences for affected individuals, their families and society as a whole. Numerous studies have implicated brain-derived neurotrophic factor
Externí odkaz:
https://doaj.org/article/2eb0704e7bb148ed81674a626ab636ad
Autor:
Skeldal, Sune, Voss, Lasse Frank, Lende, Jonas, Pedersen, Sarah Broholt, Mølgaard, Simon, Ollendorff, Mathias Kaas, Demange, Perline, Bentsen, Andreas Høiberg, Fuglsang, Marie, Sander, Marie Rubin, Buttenschøn, Henriette, Gustafsen, Camilla, Madsen, Peder, Glerup, Simon
Publikováno v:
In Journal of Biological Chemistry July 2023
Autor:
David J. Porteous, Mairead L. Bermingham, Jonathan Phillips, Rosie M. Walker, Divya Pandya, Mathias Kaas, Catherine M. Abbott, Panagiotis Giannopoulos, Katerina O. Gospodinova, Susan Anderson, Ditte Olsen, Tara L. Spires-Jones, Abigail L. Payne, Kathryn L. Evans, Simon Glerup
Publikováno v:
Gospodinova, K O, Olsen, D, Kaas, M, Anderson, S M, Phillips, J, Walker, R M, Bermingham, M L, Payne, A L, Giannopoulos, P, Pandya, D, Spires-Jones, T L, Abbott, C M, Porteous, D J, Glerup, S & Evans, K L 2021, ' Loss of SORCS2 is Associated with Neuronal DNA Double-Strand Breaks ', Cellular and molecular neurobiology . https://doi.org/10.1007/s10571-021-01163-7
SORCS2 is one of five proteins that constitute the Vps10p-domain receptor family. Members of this family play important roles in cellular processes linked to neuronal survival, differentiation and function. Genetic and functional studies implicate SO
Autor:
Angela Pärn, Ditte Olsen, Jürgen Tuvikene, Mathias Kaas, Ekaterina Borisova, Mesut Bilgin, Mie Elhauge, Joachim Vilstrup, Peder Madsen, Mateusz C. Ambrozkiewicz, Roman U. Goz, Tõnis Timmusk, Victor Tarabykin, Camilla Gustafsen, Simon Glerup
Publikováno v:
Pärn, A, Olsen, D, Tuvikene, J, Kaas, M, Borisova, E, Bilgin, M, Elhauge, M, Vilstrup, J, Madsen, P, Ambrozkiewicz, M C, Goz, R U, Timmusk, T, Tarabykin, V, Gustafsen, C & Glerup, S 2022, ' PCSK9 deficiency alters brain lipid composition without affecting brain development and function ', Frontiers in Molecular Neuroscience, vol. 15, pp. 1084633 . https://doi.org/10.3389/fnmol.2022.1084633
PCSK9 induces lysosomal degradation of the low-density lipoprotein (LDL) receptor (LDLR) in the liver, hereby preventing removal of LDL cholesterol from the circulation. Accordingly, PCSK9 inhibitory antibodies and siRNA potently reduce LDL cholester
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3581b02e08f0a7fb6ef1652b1549c718
https://pure.au.dk/portal/da/publications/pcsk9-deficiency-alters-brain-lipid-composition-without-affecting-brain-development-and-function(0bf5ac93-a0f7-4784-a89e-304623a8fe54).html
https://pure.au.dk/portal/da/publications/pcsk9-deficiency-alters-brain-lipid-composition-without-affecting-brain-development-and-function(0bf5ac93-a0f7-4784-a89e-304623a8fe54).html
Autor:
Katerina O, Gospodinova, Ditte, Olsen, Mathias, Kaas, Susan M, Anderson, Jonathan, Phillips, Rosie M, Walker, Mairead L, Bermingham, Abigail L, Payne, Panagiotis, Giannopoulos, Divya, Pandya, Tara L, Spires-Jones, Catherine M, Abbott, David J, Porteous, Simon, Glerup, Kathryn L, Evans
Publikováno v:
Cellular and molecular neurobiology.
SORCS2 is one of five proteins that constitute the Vps10p-domain receptor family. Members of this family play important roles in cellular processes linked to neuronal survival, differentiation and function. Genetic and functional studies implicate SO
Autor:
Anders D. Børglum, Linda Kaerlev, Mathias Kaas, Henriette N. Buttenschøn, Camilla Gustafsen, Ditte Demontis, Betina Elfving, Simon Molgaard, Simon Glerup, Ole Mors, Claus Munck Petersen
Publikováno v:
Buttenschøn, H N, Demontis, D, Ollendorff, M K, Elfving, B, Jensen, S M, Gustafsen, C, Kærlev, L, Petersen, C M, Børglum, A, Mors, O & Pedersen, S G 2015, ' Increased serum levels of sortilin are associated with depression and correlated with BDNF and VEGF ', Translational Psychiatry, vol. 5, no. e677 . https://doi.org/10.1038/tp.2015.167
Translational Psychiatry
Buttenschøn, H N, Demontis, D, Kaas, M, Elfving, B, Mølgaard, S, Gustafsen, C, Kaerlev, L, Petersen, C M, Børglum, A D, Mors, O & Glerup, S 2015, ' Increased serum levels of sortilin are associated with depression and correlated with BDNF and VEGF ', Translational Psychiatry, vol. 5, no. 11, e677 . https://doi.org/10.1038/tp.2015.167
Translational Psychiatry
Buttenschøn, H N, Demontis, D, Kaas, M, Elfving, B, Mølgaard, S, Gustafsen, C, Kaerlev, L, Petersen, C M, Børglum, A D, Mors, O & Glerup, S 2015, ' Increased serum levels of sortilin are associated with depression and correlated with BDNF and VEGF ', Translational Psychiatry, vol. 5, no. 11, e677 . https://doi.org/10.1038/tp.2015.167
Neurotrophic factors have been investigated in relation to depression. The aim of the present study was to widen this focus to sortilin, a receptor involved in neurotrophic signalling. The serum sortilin level was investigated in 152 individuals with
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7ef2cc8c19cb3186711de84091d2c8b7
https://pure.au.dk/portal/da/publications/increased-serum-levels-of-sortilin-are-associated-with-depression-and-correlated-with-bdnf-and-vegf(c4730819-d2c3-4578-8883-cceed5f9cda8).html
https://pure.au.dk/portal/da/publications/increased-serum-levels-of-sortilin-are-associated-with-depression-and-correlated-with-bdnf-and-vegf(c4730819-d2c3-4578-8883-cceed5f9cda8).html
Publikováno v:
Olsen, D, Kaas, M, Schwartz, O, Nykjaer, A & Glerup, S 2013, ' Loss of BDNF or its receptors in three mouse models has unpredictable consequences for anxiety and fear acquisition ', Learning & Memory (Online), vol. 20, no. 9, pp. 499-504 . https://doi.org/10.1101/lm.032045.113
BDNF-induced signaling is essential for the development of the central nervous system and critical for plasticity in adults. Mature BDNF signals through TrkB, while its precursor proBDNF employs p75NTR, resulting in activation of signaling cascades w
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d05b3979c49d68efaf4d68e6c1d438d7
https://pure.au.dk/portal/da/publications/loss-of-bdnf-or-its-receptors-in-three-mouse-models-has-unpredictable-consequences-for-anxiety-and-fear-acquisition(9fb67ffc-7cb1-4d28-8271-cc4a155dd1a0).html
https://pure.au.dk/portal/da/publications/loss-of-bdnf-or-its-receptors-in-three-mouse-models-has-unpredictable-consequences-for-anxiety-and-fear-acquisition(9fb67ffc-7cb1-4d28-8271-cc4a155dd1a0).html
Autor:
Henriette Buttenschøn, Ditte Demontis, Mathias Kaas, Betina Elfving, simon mølgaard, Camilla Gustafsen, Linda Kærlev, Claus Munck Petersen, Anders Børglum, Ole Mors, Simon Glerup Pedersen
Publikováno v:
Aarhus University
Buttenschøn, H N, Demontis, D, Kaas, M, Elfving, B, mølgaard, S, Gustafsen, C, Kærlev, L, Petersen, C M, Børglum, A, Mors, O & Pedersen, S G 2015, ' Increased sortilin in depression ' .
Buttenschøn, H N, Demontis, D, Kaas, M, Elfving, B, mølgaard, S, Gustafsen, C, Kærlev, L, Petersen, C M, Børglum, A, Mors, O & Pedersen, S G 2015, ' Increased sortilin in depression ' .
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=dedup_wf_001::55e40d2a7551766cb6c07c6d78039323
https://pure.au.dk/portal/en/publications/increased-sortilin-in-depression(61654f7a-418e-4d6a-882d-a5e351a29116).html
https://pure.au.dk/portal/en/publications/increased-sortilin-in-depression(61654f7a-418e-4d6a-882d-a5e351a29116).html