Zobrazeno 1 - 10
of 250
pro vyhledávání: '"Mathias Hafner"'
Autor:
Mario Vitacolonna, Roman Bruch, Ane Agaçi, Elina Nürnberg, Tiziana Cesetti, Florian Keller, Francesco Padovani, Simeon Sauer, Kurt M. Schmoller, Markus Reischl, Mathias Hafner, Rüdiger Rudolf
Publikováno v:
Frontiers in Bioengineering and Biotechnology, Vol 12 (2024)
Spheroids have become principal three-dimensional models to study cancer, developmental processes, and drug efficacy. Single-cell analysis techniques have emerged as ideal tools to gauge the complexity of cellular responses in these models. However,
Externí odkaz:
https://doaj.org/article/5c372ecc69c441dca89fee11ea6b5c66
Autor:
Nathalie Couturier, Sarah Janice Hörner, Elina Nürnberg, Claudio Joazeiro, Mathias Hafner, Rüdiger Rudolf
Publikováno v:
Frontiers in Cell and Developmental Biology, Vol 12 (2024)
Familial amyotrophic lateral sclerosis (ALS) is a progressive neuromuscular disorder that is due to mutations in one of several target genes, including SOD1. So far, clinical records, rodent studies, and in vitro models have yielded arguments for eit
Externí odkaz:
https://doaj.org/article/822ebd57284d4eb0ae75f847475eab36
Autor:
Sarah Janice Hörner, Nathalie Couturier, Daniele Caroline Gueiber, Mathias Hafner, Rüdiger Rudolf
Publikováno v:
Cells, Vol 11, Iss 23, p 3753 (2022)
Schwann cells are glial cells of the peripheral nervous system. They exist in several subtypes and perform a variety of functions in nerves. Their derivation and culture in vitro are interesting for applications ranging from disease modeling to tissu
Externí odkaz:
https://doaj.org/article/939578da382b49aaa1e3944aaa1d3677
Autor:
Elena von Molitor, Katja Riedel, Michael Krohn, Mathias Hafner, Rüdiger Rudolf, Tiziana Cesetti
Publikováno v:
Frontiers in Human Neuroscience, Vol 15 (2021)
Sweetness is the preferred taste of humans and many animals, likely because sugars are a primary source of energy. In many mammals, sweet compounds are sensed in the tongue by the gustatory organ, the taste buds. Here, a group of taste bud cells expr
Externí odkaz:
https://doaj.org/article/0e5e6d557f684e98ab00535a501715b8
Publikováno v:
BMC Cancer, Vol 19, Iss 1, Pp 1-14 (2019)
Abstract Background Different 3D-cell culture approaches with varying degrees of complexity have been developed to serve as melanoma models for drug testing or mechanistic studies. While these 3D-culture initiatives are already often superior to clas
Externí odkaz:
https://doaj.org/article/19428020944e477db0ff0cd4938d19b0
Autor:
Tatjana Straka, Charlotte Schröder, Andreas Roos, Laxmikanth Kollipara, Albert Sickmann, Marion Patrick Ivey Williams, Mathias Hafner, Muzamil Majid Khan, Rüdiger Rudolf
Publikováno v:
Frontiers in Physiology, Vol 12 (2021)
Recent studies have demonstrated that neuromuscular junctions are co-innervated by sympathetic neurons. This co-innervation has been shown to be crucial for neuromuscular junction morphology and functional maintenance. To improve our understanding of
Externí odkaz:
https://doaj.org/article/3ac8874caba44a999e361a9dee45caed
Autor:
Sarah Wahby, Jonas Jarczyk, Alexander Fierek, Jakob Heinkele, Cleo-Aron Weis, Markus Eckstein, Thomas Martini, Stefan Porubsky, Mathias Hafner, Philipp Erben
Publikováno v:
Translational Oncology, Vol 14, Iss 1, Pp 100900- (2021)
Muscle-invasive bladder cancer (MIBC) is characterized by high recurrence and rapid progression. Progression is linked to changes in glycan structures and altered levels of glycosyltransferases. The relationship of mRNA expression by glycosyltransfer
Externí odkaz:
https://doaj.org/article/f7d66227355846939a463a55c700128a
Autor:
Maximilian E. A. Schäfer, Florian Keller, Jens Schumacher, Heinrich Haas, Fulvia Vascotto, Ugur Sahin, Mathias Hafner, Rüdiger Rudolf
Publikováno v:
Cells, Vol 11, Iss 6, p 1026 (2022)
Cancer therapy is an emergent application for mRNA therapeutics. While in tumor immunotherapy, mRNA encoding for tumor-associated antigens is delivered to antigen-presenting cells in spleen and lymph nodes, other therapeutic options benefit from imme
Externí odkaz:
https://doaj.org/article/13bfef6b877d45cea48456279596b567
Autor:
Matteo Rigon, Sarah Janice Hörner, Tatjana Straka, Karen Bieback, Norbert Gretz, Mathias Hafner, Rüdiger Rudolf
Publikováno v:
Frontiers in Molecular Neuroscience, Vol 13 (2020)
Amongst other approaches, adipose-derived stromal cells (ASCs) have recently been tested with respect to their regenerative capacity for treatment of neuromuscular disorders. While beneficial effects of ASCs on muscle recovery were observed previousl
Externí odkaz:
https://doaj.org/article/d156ea304c954fe28179130a3ff494ce
Autor:
Elina Nürnberg, Mario Vitacolonna, Julia Klicks, Elena von Molitor, Tiziana Cesetti, Florian Keller, Roman Bruch, Torsten Ertongur-Fauth, Katja Riedel, Paul Scholz, Thorsten Lau, Richard Schneider, Julia Meier, Mathias Hafner, Rüdiger Rudolf
Publikováno v:
Frontiers in Molecular Biosciences, Vol 7 (2020)
Three-dimensional cell cultures, such as spheroids and organoids, serve as increasingly important models in fundamental and applied research and start to be used for drug screening purposes. Optical tissue clearing procedures are employed to enhance
Externí odkaz:
https://doaj.org/article/e9a4a5c801864dedbf88f27ca486f92c