Zobrazeno 1 - 10
of 10
pro vyhledávání: '"Mathias Gotsmy"'
Autor:
Guido Schlögel, Rüdiger Lück, Stefan Kittler, Oliver Spadiut, Julian Kopp, Jürgen Zanghellini, Mathias Gotsmy
Publikováno v:
Computational and Structural Biotechnology Journal, Vol 23, Iss , Pp 3651-3661 (2024)
Biotechnological production of recombinant molecules relies heavily on fed-batch processes. However, as the cells' growth, substrate uptake, and production kinetics are often unclear, the fed-batches are frequently operated under sub-optimal conditio
Externí odkaz:
https://doaj.org/article/6983b0e5badc40938f42463311c9a8c0
Autor:
Mathias Gotsmy, Florian Strobl, Florian Weiß, Petra Gruber, Barbara Kraus, Juergen Mairhofer, Jürgen Zanghellini
Publikováno v:
Microbial Cell Factories, Vol 22, Iss 1, Pp 1-16 (2023)
Abstract Plasmid DNA (pDNA) is a key biotechnological product whose importance became apparent in the last years due to its role as a raw material in the messenger ribonucleic acid (mRNA) vaccine manufacturing process. In pharmaceutical production pr
Externí odkaz:
https://doaj.org/article/70273fc1ce8e443c95047315ca625696
Publikováno v:
BMC Bioinformatics, Vol 23, Iss 1, Pp 1-30 (2022)
Abstract Metabolomic time course analyses of biofluids are highly relevant for clinical diagnostics. However, many sampling methods suffer from unknown sample sizes, commonly known as size effects. This prevents absolute quantification of biomarkers.
Externí odkaz:
https://doaj.org/article/fe834cc27d9443e4a5f1d5f4b3349b03
Autor:
Julia Brunmair, Mathias Gotsmy, Laura Niederstaetter, Benjamin Neuditschko, Andrea Bileck, Astrid Slany, Max Lennart Feuerstein, Clemens Langbauer, Lukas Janker, Jürgen Zanghellini, Samuel M. Meier-Menches, Christopher Gerner
Publikováno v:
Nature Communications, Vol 12, Iss 1, Pp 1-13 (2021)
Biomonitoring of sweat from fingertips overcomes current limitations in time-resolved metabolomic profiling of humans and may prove to become a powerful, noninvasive tool for precision medicine. Here, in a feasibility study of short interval sampling
Externí odkaz:
https://doaj.org/article/4fc1196107f94af98aae222ec98214f4
Autor:
Gordana Wozniak-Knopp, Gerhard Stadlmayr, Jan Walther Perthold, Katharina Stadlbauer, Mathias Gotsmy, Stefan Becker, Florian Rüker
Publikováno v:
PLoS ONE, Vol 13, Iss 4, p e0195442 (2018)
We have designed a complete antibody-like construct where the CH1 and Cκ domains are exchanged for a pair of the CH3 domains and efficient pairing of the heavy and light variable domain is achieved using "Knobs-into-Holes" strategy. This construct,
Externí odkaz:
https://doaj.org/article/6fd29778184a4a0396484ba2c6136214
Autor:
Mathias Gotsmy, Florian Strobl, Florian Weiß, Petra Gruber, Barbara Kraus, Juergen Mairhofer, Jürgen Zanghellini
Plasmid DNA (pDNA) is a key biotechnological product whose importance became apparent in the last years due to its role as a raw material in the messenger ribonucleic acid (mRNA) vaccine manufacturing process. In pharmaceutical production processes,
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::92fc156faff8707795cb2ce23cd79ac1
https://doi.org/10.1101/2023.02.09.527815
https://doi.org/10.1101/2023.02.09.527815
Autor:
Jürgen Zanghellini, Laura Niederstaetter, Andrea Bileck, Julia Brunmair, Astrid Slany, Samuel M. Meier-Menches, Clemens Langbauer, Benjamin Neuditschko, Christopher Gerner, Lukas Janker, Max Lennart Feuerstein, Mathias Gotsmy
Publikováno v:
Nature Communications
Nature Communications, Vol 12, Iss 1, Pp 1-13 (2021)
Nature Communications, Vol 12, Iss 1, Pp 1-13 (2021)
Metabolic biomonitoring in humans is typically based on the sampling of blood, plasma or urine. Although established in the clinical routine, these sampling procedures are often associated with a variety of compliance issues, which are impeding time-
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ccdff07383acc5cfdcab867eb1c5f0cf
http://europepmc.org/articles/PMC8514494
http://europepmc.org/articles/PMC8514494
Publikováno v:
Proteins
Alongside inorganic materials, water, and air, soil organic matter (SOM) is one of the major components of soil and has tremendous influence on the environment given its vital role in the carbon cycle. Many soil dwelling organisms like plants, fungi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2f0c3c027155c16140dfc01aab45acf1
https://pubmed.ncbi.nlm.nih.gov/33675059
https://pubmed.ncbi.nlm.nih.gov/33675059
Autor:
Florian Rüker, Mathias Gotsmy, Gordana Wozniak-Knopp, Jan Walther Perthold, Katharina Stadlbauer, Gerhard Stadlmayr, Stefan Becker
Publikováno v:
PLoS ONE, Vol 13, Iss 4, p e0195442 (2018)
PLoS ONE
PLoS ONE
We have designed a complete antibody-like construct where the CH1 and Cκ domains are exchanged for a pair of the CH3 domains and efficient pairing of the heavy and light variable domain is achieved using “Knobs-into-Holes” strategy. This constru
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::22383a93e7f7750ef664be4c85b10db2
http://europepmc.org/articles/PMC5891013?pdf=render
http://europepmc.org/articles/PMC5891013?pdf=render