Zobrazeno 1 - 10
of 16
pro vyhledávání: '"Mathias G. Svahn"'
Autor:
Per-Ola Carlsson, Daniel Espes, Sofia Sisay, Lindsay C. Davies, C. I. Edvard Smith, Mathias G. Svahn
Publikováno v:
Diabetologia.
Aim/hypothesis This study aimed to investigate the safety and efficacy of treatment with allogeneic Wharton’s jelly-derived mesenchymal stromal cells (MSCs) in recent-onset type 1 diabetes. Methods A combined Phase I/II trial, composed of a dose es
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::f9caaf3489987e603d25dd776acf8bbe
https://doi.org/10.1007/s00125-023-05934-3
https://doi.org/10.1007/s00125-023-05934-3
Autor:
Mathias G. Svahn, Per-Ola Carlsson
Publikováno v:
Clinical Trials in Degenerative Diseases, Vol 3, Iss 2, Pp 32-37 (2018)
Background and objectives: The Wharton’s jelly of the umbilical cord tissue contains a high density of mesenchymal stromal cells (MSCs). Wharton’s jelly derived mesenchymal stromal cells have immunosuppressive potential that can be utilized for t
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::48319c37a8b49dac2689f58463d8b490
http://www.clinicaltdd.com/article.asp?issn=2542-3975
http://www.clinicaltdd.com/article.asp?issn=2542-3975
Autor:
Karin E. Lundin, Iulian I. Oprea, Mathias G. Svahn, Pedro Moreno, C. I. Edvard Smith, Oscar E. Simonson, Eman M. Zaghloul
Publikováno v:
Genetica. 137:47-56
In both basic research as well as experimental gene therapy the need to transfer genetic material into a cell is of vital importance. The cellular compartment, which is the target for the genetic material, depends upon application. An siRNA that medi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e269cde12abbfb5e75c2e03e64d9561b
https://doi.org/10.1007/s10709-009-9372-0
https://doi.org/10.1007/s10709-009-9372-0
Publikováno v:
Nucleosides, Nucleotides and Nucleic Acids. 26:1501-1504
As initial studies of block coupling of peptides with C-terminal glycines, we have evaluated of coupling of glycine building blocks under various conditions to a preassembled solid support bound LNA-fragment. Potentially competing side reaction have
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::be940cb97412d4bed98d85e5ea652d0e
https://doi.org/10.1080/15257770701542934
https://doi.org/10.1080/15257770701542934
Publikováno v:
Karolinska Institutet
Non-viral gene delivery is an important approach in order to establish safe in vivo gene therapy in the clinic. Although viral vectors currently exhibit superior gene transfer efficacy, the safety aspect of viral gene delivery is a concern. In order
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::02c20bb427aaa6eff79d453142471dd3
https://doi.org/10.2174/138161205774580813
https://doi.org/10.2174/138161205774580813
Publikováno v:
Journal of Controlled Release. 98:169-177
Linking peptide functions directly to nucleic acids can be used to improve transfection. We have previously demonstrated this by sequence-specific hybridization of a bifunctional peptide nucleic acid (PNA) consisting of a nucleic acid binding moiety
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::20190904ae6bcec2888d91016be24240
https://doi.org/10.1016/j.jconrel.2004.04.012
https://doi.org/10.1016/j.jconrel.2004.04.012
Autor:
Mathias G. Svahn, Mikael Leijon, Karin E. Lundin, Rongbin Ge, Lars Branden, C. I. Edvard Smith, Elisabeth Törnquist
Publikováno v:
Biomolecular Engineering. 21:51-59
Peptide nucleic acid (PNA) is a DNA analog with broad biotechnical applications, and possibly also treatment applications. Its suggested uses include that of a specific anchor sequence for biologically active peptides to plasmids in a sequence-specif
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0965993913301d2a3dc6271ae02f9f65
https://doi.org/10.1016/j.bioeng.2003.10.003
https://doi.org/10.1016/j.bioeng.2003.10.003
Autor:
Pedro Moreno, C. I. Edvard Smith, Oscar E. Simonson, Mathias G. Svahn, Karin E. Lundin, Roger Strömberg, Malgorzata Wenska
Publikováno v:
Nucleic acids symposium series (2004). (52)
The Bioplex technology allows the hybridization of functional entities to various forms of nucleic acids by the use of synthetic nucleic acid analogs. Such supramolecular assemblies can be made in a predetermined fashion and can confer new properties
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2b7b6b09045e86932688191b2c1270b3
https://pubmed.ncbi.nlm.nih.gov/18776236
https://pubmed.ncbi.nlm.nih.gov/18776236
Autor:
Mathias G. Svahn, Kersten S. Rabe, Geoffrey Barger, Samir EL-Andaloussi, Oscar E. Simonson, Boturyn Didier, Renaudet Olivier, Pascal Dumy, Lars J. Brandén, Christof M. Niemeyer, C. I. Edvard Smith, Wolfgang Fritzsche, Frank Bier
Publikováno v:
AIP Conference Proceedings. 1062
Finding the optimal combinations of ligands for tissue-specific delivery is tedious even if only a few well-established compounds are tested. The cargo affects the receptor-ligand interaction, especially when it is charged like DNA. The ligand should
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1649ba491769685c44bea07323b16d35
http://ora.ox.ac.uk/objects/uuid:fc8d4bb9-b115-471c-b037-1fcd7ee8c489
http://ora.ox.ac.uk/objects/uuid:fc8d4bb9-b115-471c-b037-1fcd7ee8c489
Autor:
Karin E. Lundin, Oscar E. Simonson, Mathias G. Svahn, C. I. Edvard Smith, Abdalla J. Mohamed, Rongbin Ge
Publikováno v:
The journal of gene medicine. 10(1)
Background RNA polymerase III (pol III)-dependent transcripts are involved in many fundamental activities in a cell, such as splicing and protein synthesis. They also regulate cell growth and influence tumor formation. During recent years vector-base
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f71358b87f98f9cd33532e36ac55dc2f
https://pubmed.ncbi.nlm.nih.gov/18023071
https://pubmed.ncbi.nlm.nih.gov/18023071