Zobrazeno 1 - 10
of 32
pro vyhledávání: '"Mathias Busek"'
Publikováno v:
Biosensors, Vol 12, Iss 2, p 126 (2022)
Organ-on-a-Chip (OoC) systems bring together cell biology, engineering, and material science for creating systems that recapitulate the in vivo microenvironment of tissues and organs. The versatility of OoC systems enables in vitro models for studyin
Externí odkaz:
https://doaj.org/article/c1e9afb9fbde46b8b53a67cf18580257
Autor:
Mathias Busek, Steffen Nøvik, Aleksandra Aizenshtadt, Mikel Amirola-Martinez, Thomas Combriat, Stefan Grünzner, Stefan Krauss
Publikováno v:
Biosensors, Vol 11, Iss 5, p 162 (2021)
Polydimethylsiloxane (PDMS) has been used in microfluidic systems for years, as it can be easily structured and its flexibility makes it easy to integrate actuators including pneumatic pumps. In addition, the good optical properties of the material a
Externí odkaz:
https://doaj.org/article/75122455b1bb456faab8a5981c2dc61b
Autor:
Anthony Beck, Franziska Obst, Mathias Busek, Stefan Grünzner, Philipp J. Mehner, Georgi Paschew, Dietmar Appelhans, Brigitte Voit, Andreas Richter
Publikováno v:
Micromachines, Vol 11, Iss 5, p 479 (2020)
The interest in large-scale integrated (LSI) microfluidic systems that perform high-throughput biological and chemical laboratory investigations on a single chip is steadily growing. Such highly integrated Labs-on-a-Chip (LoC) provide fast analysis,
Externí odkaz:
https://doaj.org/article/f9c52754a0d946bab1cc99841a85e33f
Autor:
Jessie Pöche, Anna Dmitrieva, Konstanze Fisher, Tomasz Kolanowski, Sinah Hansen, Stefan Grünzner, Mario Schubert, Kaomei Guan, Ali El-Armouche, Mathias Busek, Björn Binnewerg, Frank Sonntag, Florian Schmieder, Andreas Richter
Publikováno v:
Acta Biomaterialia. 102:273-286
The lack of a fully developed human cardiac model in vitro hampers the progress of many biomedical research fields including pharmacology, developmental biology, and disease modeling. Currently, available methods may only differentiate human induced
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::75c68d3495d94e5f62e8429cfd4c2f23
https://doi.org/10.1016/j.actbio.2019.11.044
https://doi.org/10.1016/j.actbio.2019.11.044
Organ-on-a-Chip (OoC) systems bring together cell biology, engineering, and material science for creating systems that recapitulate the in vivo microenvironment of tissues and organs. The versatility of OoC systems enables in vitro models for studyin
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f2df18cdd72d237cf9d90688661dc654
Autor:
Frank Sonntag, Uwe Marschner, Mario Schubert, Kaomei Guan, Florian Schmieder, Mathias Busek, Andreas Richter
Publikováno v:
Current Directions in Biomedical Engineering. 5:269-272
Recently, we could demonstrate positive effects of microfluidic cultivation conditions on maturation of cardiomyocytes derived from human induced pluripotent stem cells (iPS-CMs) in a 2D model. However, 3D cell culture models are much closer to physi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::110ccc6f36fe510ec05e8887e5e2f77a
https://doi.org/10.1515/cdbme-2019-0068
https://doi.org/10.1515/cdbme-2019-0068
Publikováno v:
Current Directions in Biomedical Engineering, Vol 3, Iss 2, Pp 363-366 (2017)
To improve cell vitality, sufficient oxygen supply is an important factor. A deficiency in oxygen is called Hypoxia and can influence for example tumor growth or inflammatory processes. Hypoxia assays are usually performed with the help of animal or
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d19a712a88e4ac6a0433a5175bf48aa9
https://doi.org/10.1515/cdbme-2017-0075
https://doi.org/10.1515/cdbme-2017-0075
Autor:
Frank Sonntag, Tomasz Kolanowski, Christian Steinfelder, Stefan Grünzner, Kaomei Guan, Mathias Busek
Publikováno v:
Current Directions in Biomedical Engineering, Vol 3, Iss 2, Pp 367-370 (2017)
Hereby a microfluidic system for cell cultivation is presented in which human pluripotent stem cell-derived cardiomyocytes were cultivated under perfusion. Besides micro-perfusion this system is also capable to produce well-defined oxygen contents, a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::59480aa11ead2ef4acc88a803002cea8
https://doaj.org/article/036809fa7f834a8eb2a168c56cf32d99
https://doaj.org/article/036809fa7f834a8eb2a168c56cf32d99
Autor:
Andreas Voigt, Philipp J. Mehner, Uwe Marschner, Mathias Busek, Anthony Beck, Andreas Richter
Publikováno v:
ASME 2019 Conference on Smart Materials, Adaptive Structures and Intelligent Systems.
We propose a planar hydrogel-based micro-valve design which is modeled as a library element for Matlab Simulink. For this test case, a pressure pump (voltage source) in series with a micro-valve model (variable fluidic resistance) is built up. The mi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::dc15a5d311660733075f4d667b655899
https://doi.org/10.1115/smasis2019-5614
https://doi.org/10.1115/smasis2019-5614
Autor:
Thomas Combriat, Mikel Amirola-Martinez, Mathias Busek, Steffen Novik, Stefan Krauss, Stefan Grünzner, Aleksandra Aizenshtadt
Publikováno v:
Biosensors
Volume 11
Issue 5
Biosensors, Vol 11, Iss 162, p 162 (2021)
Volume 11
Issue 5
Biosensors, Vol 11, Iss 162, p 162 (2021)
Polydimethylsiloxane (PDMS) has been used in microfluidic systems for years, as it can be easily structured and its flexibility makes it easy to integrate actuators including pneumatic pumps. In addition, the good optical properties of the material a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ee744ba9d81afa770bc23395cdd31974
https://doi.org/10.3390/bios11050162
https://doi.org/10.3390/bios11050162