Zobrazeno 1 - 10
of 36
pro vyhledávání: '"Mathias Bruegel"'
Autor:
Helen Graf, Caroline Gräfe, Mathias Bruegel, Felix L. Happich, Vassilissa Wustrow, Aljoscha Wegener, Wolfgang Wilfert, Michael Zoller, Uwe Liebchen, Michael Paal, Christina Scharf
Publikováno v:
Infectious Diseases and Therapy, Vol 13, Iss 9, Pp 2089-2101 (2024)
Abstract Introduction The release of pro-inflammatory cytokines in critically ill patients with sepsis leads to endothelial dysfunction resulting in cardiocirculatory insufficiency. Their extracorporeal elimination using the cytokine adsorber CytoSor
Externí odkaz:
https://doaj.org/article/143819681fb243d69786ff613a62babd
Autor:
Helen Graf, Caroline Gräfe, Mathias Bruegel, Michael Zoller, Nils Maciuga, Sandra Frank, Lorenz Weidhase, Michael Paal, Christina Scharf
Publikováno v:
Annals of Intensive Care, Vol 14, Iss 1, Pp 1-11 (2024)
Abstract Background Rhabdomyolysis is a serious condition that can lead to acute kidney injury with the need of renal replacement therapy (RRT). The cytokine adsorber Cytosorb® (CS) can be used for extracorporeal myoglobin elimination in patients wi
Externí odkaz:
https://doaj.org/article/067e3c59423447df8373dfcd9799b469
Autor:
Caroline Gräfe, Uwe Liebchen, Antonia Greimel, Nils Maciuga, Mathias Bruegel, Michael Irlbeck, Lorenz Weidhase, Michael Zoller, Michael Paal, Christina Scharf
Publikováno v:
Renal Failure, Vol 45, Iss 2 (2023)
Severe rhabdomyolysis frequently results in acute kidney injury (AKI) due to myoglobin accumulation with the need of kidney replacement therapy (KRT). The present study investigated whether the application of Cytosorb® (CS) led to an increased rate
Externí odkaz:
https://doaj.org/article/0c4648b2a6f743d99fe093eedc9a5a10
Autor:
Philipp E Geyer, Florian M Arend, Sophia Doll, Marie‐Luise Louiset, Sebastian Virreira Winter, Johannes B Müller‐Reif, Furkan M Torun, Michael Weigand, Peter Eichhorn, Mathias Bruegel, Maximilian T Strauss, Lesca M Holdt, Matthias Mann, Daniel Teupser
Publikováno v:
EMBO Molecular Medicine, Vol 13, Iss 8, Pp 1-16 (2021)
Abstract A deeper understanding of COVID‐19 on human molecular pathophysiology is urgently needed as a foundation for the discovery of new biomarkers and therapeutic targets. Here we applied mass spectrometry (MS)‐based proteomics to measure seru
Externí odkaz:
https://doaj.org/article/00b8cf3b6b574c2fbf649a6d4e6a5b24
Autor:
Marie-Luise Buchholtz, Florian M Arend, Peter Eichhorn, Michael Weigand, Alisa Kleinhempel, Kurt Häusler, Mathias Bruegel, Lesca M Holdt, Daniel Teupser
Publikováno v:
PLoS ONE, Vol 16, Iss 5, p e0251587 (2021)
ObjectivesDuring the COVID-19 pandemic, SARS-CoV-2 antibody testing has been suggested for (1) screening populations for disease prevalence, (2) diagnostics, and (3) guiding therapeutic applications. Here, we conducted a detailed clinical evaluation
Externí odkaz:
https://doaj.org/article/69b0a9b74a0d482ca770d6ff8849e151
Autor:
Louise Füessl, Tobias Lau, Isaac Lean, Sandra Hasmann, Bernhard Riedl, Florian M. Arend, Johanna Sorodoc-Otto, Daniela Soreth-Rieke, Marcell Toepfer, Simon Rau, Haxhrije Salihi-Halimi, Michael Paal, Wilke Beuthien, Norbert Thaller, Yana Suttmann, Gero von Gersdorff, Ron Regenauer, Anke von Bergwelt-Baildon, Daniel Teupser, Mathias Bruegel, Michael Fischereder, Ulf Schönermarck
Publikováno v:
Vaccines, Vol 10, Iss 4, p 605 (2022)
Short-term studies have shown an attenuated immune response in hemodialysis patients after COVID-19-vaccination. The present study examines how antibody response is maintained after vaccination against SARS-CoV-2 in a large population of hemodialysis
Externí odkaz:
https://doaj.org/article/a091a6de7bc9417a904a23c2a59f0438
Autor:
Daniel Tiller, Martin Russ, Karin Halina Greiser, Sebastian Nuding, Henning Ebelt, Alexander Kluttig, Jan A Kors, Joachim Thiery, Mathias Bruegel, Johannes Haerting, Karl Werdan
Publikováno v:
PLoS ONE, Vol 8, Iss 3, p e59225 (2013)
BACKGROUND/OBJECTIVES: Chronic heart failure (CHF) is one of the most important public health concerns in the industrialized world having increasing incidence and prevalence. Although there are several studies describing the prevalence of heart failu
Externí odkaz:
https://doaj.org/article/0663c582bd3a4ac2a6210c3574875df9
Autor:
Ulrike Mütze, Skadi Beblo, Linda Kortz, Claudia Matthies, Berthold Koletzko, Mathias Bruegel, Carmen Rohde, Joachim Thiery, Wieland Kiess, Uta Ceglarek
Publikováno v:
PLoS ONE, Vol 7, Iss 8, p e43021 (2012)
BACKGROUND: Patients with phenylketonuria (PKU) have to follow a lifelong phenylalanine restricted diet. This type of diet markedly reduces the intake of saturated and unsaturated fatty acids especially long chain polyunsaturated fatty acids (LC-PUFA
Externí odkaz:
https://doaj.org/article/08e769028ea34085a133d69453dc3973
Autor:
Stefanie Völk, Fabian Dobler, Uwe Koedel, Hans‐Walter Pfister, Mathias Bruegel, Sören Schubert, Matthias Klein
Publikováno v:
European Journal of Neurology. 30:702-709
Meningitis and encephalitis are potentially life-threatening diseases that require fast and accurate diagnostics and therapy. The value of polymerase chain reaction (PCR) multiplex testing in clinical practice is still a matter of debate. This study
Autor:
Anne-Sophie Kalla, Michael Vogeser, Susanne Nährig, Mathias Bruegel, Katharina Habler, Michael Paal, Daniel Teupser, Michael Rychlik
Publikováno v:
Clinical Chemistry and Laboratory Medicine (CCLM). 60:82-91
Objectives Cystic fibrosis (CF) transmembrane conductance regulator (CFTR) modulators have revolutionized the therapeutic landscape in CF treatment. These vital drugs are extensively metabolized via CYP3A, so caution must be exercised in multimodal C