Zobrazeno 1 - 10
of 63
pro vyhledávání: '"Mathias, Schmelcher"'
Autor:
Christian Roehrig, Markus Huemer, Dominique Lorgé, Fabienne Arn, Nadine Heinrich, Lavanja Selvakumar, Lynn Gasser, Patrick Hauswirth, Chun-Chi Chang, Tiziano A. Schweizer, Fritz Eichenseher, Steffi Lehmann, Annelies S. Zinkernagel, Mathias Schmelcher
Publikováno v:
mBio, Vol 15, Iss 2 (2024)
ABSTRACT Bacterial infections are a growing global healthcare concern, as an estimated annual 4.95 million deaths are associated with antimicrobial resistance (AMR). Methicillin-resistant Staphylococcus aureus is one of the deadliest pathogens and a
Externí odkaz:
https://doaj.org/article/49556bdc79fb40e0848bc9a5790f6e34
Autor:
Anja P. Keller, Markus Huemer, Chun-Chi Chang, Srikanth Mairpady Shambat, Caroline Bjurnemark, Nicole Oberortner, Michaela V. Santschi, Léa V. Zinsli, Christian Röhrig, Anna M. Sobieraj, Yang Shen, Fritz Eichenseher, Annelies S. Zinkernagel, Martin J. Loessner, Mathias Schmelcher
Publikováno v:
mBio, Vol 14, Iss 5 (2023)
ABSTRACT The current standard of treatment for chronic staphylococcal osteomyelitis entails high doses of antibiotics over the course of several weeks. Biofilm-associated and intracellular persisters are key factors contributing to therapeutic failur
Externí odkaz:
https://doaj.org/article/6260294adfd2410d95328a1b7ada479c
Publikováno v:
Computational and Structural Biotechnology Journal, Vol 19, Iss , Pp 315-329 (2021)
Biotherapeutics, and antimicrobial proteins in particular, are of increasing interest for human medicine. An important challenge in the development of such therapeutics is their potential immunogenicity, which can induce production of anti-drug-antib
Externí odkaz:
https://doaj.org/article/4d36e4e506474904ac1fb8c9c1532c21
Autor:
Anja P. Keller, Shera Ly, Steven Daetwyler, Fritz Eichenseher, Martin J. Loessner, Mathias Schmelcher
Publikováno v:
Viruses, Vol 14, Iss 12, p 2801 (2022)
Staphylococcus aureus is a major causative agent of bovine mastitis, a disease considered one of the most economically devastating in the dairy sector. Considering the increasing prevalence of antibiotic-resistant strains, novel therapeutic approache
Externí odkaz:
https://doaj.org/article/f34d9d9efb214b22a3a82307fcd56a51
Autor:
Anna M. Sobieraj, Markus Huemer, Léa V. Zinsli, Susanne Meile, Anja P. Keller, Christian Röhrig, Fritz Eichenseher, Yang Shen, Annelies S. Zinkernagel, Martin J. Loessner, Mathias Schmelcher
Publikováno v:
mBio, Vol 11, Iss 5 (2020)
ABSTRACT Staphylococcus aureus is a human pathogen causing life-threatening diseases. The increasing prevalence of multidrug-resistant S. aureus infections is a global health concern, requiring development of novel therapeutic options. Peptidoglycan-
Externí odkaz:
https://doaj.org/article/db6d42fc26334af090638c286d488157
Autor:
Mara D. Saenz-de-Juano, Giulia Silvestrelli, Andres Weber, Christian Röhrig, Mathias Schmelcher, Susanne E. Ulbrich
Publikováno v:
Biology, Vol 11, Iss 3, p 415 (2022)
In dairy cows, Staphylococcus aureus (S. aureus) is among the most prevalent microorganisms worldwide, causing mastitis, an inflammation of the mammary gland. Production of extracellular vesicles (EVs) is a common feature of S. aureus strains, which
Externí odkaz:
https://doaj.org/article/49a32d4f3737419582874c899785f418
Autor:
Christian Röhrig, Markus Huemer, Dominique Lorgé, Samuel Luterbacher, Preeda Phothaworn, Christopher Schefer, Anna M. Sobieraj, Léa V. Zinsli, Srikanth Mairpady Shambat, Nadja Leimer, Anja P. Keller, Fritz Eichenseher, Yang Shen, Sunee Korbsrisate, Annelies S. Zinkernagel, Martin J. Loessner, Mathias Schmelcher
Publikováno v:
mBio, Vol 11, Iss 2 (2020)
ABSTRACT Staphylococcus aureus is a major concern in human health care, mostly due to the increasing prevalence of antibiotic resistance. Intracellular localization of S. aureus plays a key role in recurrent infections by protecting the pathogens fro
Externí odkaz:
https://doaj.org/article/d5ce57eae2424797bb7ba736b3e716b5
Autor:
Eric T. Sumrall, Marloes I. Hofstee, Daniel Arens, Christian Röhrig, Susanne Baertl, Dominic Gehweiler, Mathias Schmelcher, Martin J. Loessner, Stephan Zeiter, R. Geoff Richards, T. Fintan Moriarty
Publikováno v:
Antibiotics, Vol 10, Iss 10, p 1186 (2021)
Orthopaedic device-related infection (ODRI) presents a significant challenge to the field of orthopaedic and trauma surgery. Despite extensive treatment involving surgical debridement and prolonged antibiotic therapy, outcomes remain poor. This is la
Externí odkaz:
https://doaj.org/article/ba5eec9a7e5e465c9a3262f6a01744b6
Autor:
Hugo Oliveira, Sílvio Santos, Diana P. Pires, Dimitri Boeckaerts, Graça Pinto, Rita Domingues, Jennifer Otero, Yves Briers, Rob Lavigne, Mathias Schmelcher, Andreas Dötsch, Joana Azeredo
Publikováno v:
Applied Microbiology and Biotechnology, 107 (11)
The online version contains supplementary material available at https://doi.org/10.1007/s00253-023-12547-8.
Citrobacter koseri is an emerging Gram-negative bacterial pathogen, which causes urinary tract infections. We isolated and characterized
Citrobacter koseri is an emerging Gram-negative bacterial pathogen, which causes urinary tract infections. We isolated and characterized
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::cc5bbb3152dc2942cb3dc09e3ae2f1b7
https://hdl.handle.net/1822/84652
https://hdl.handle.net/1822/84652
Autor:
Johan Seijsing, Anna M. Sobieraj, Nadia Keller, Yang Shen, Annelies S. Zinkernagel, Martin J. Loessner, Mathias Schmelcher
Publikováno v:
Frontiers in Microbiology, Vol 9 (2018)
The increasing number of multidrug-resistant bacteria intensifies the need to develop new antimicrobial agents. Endolysins are bacteriophage-derived enzymes that degrade the bacterial cell wall and hold promise as a new class of highly specific and v
Externí odkaz:
https://doaj.org/article/7208ba3a8031415ca4ff598cb3fc9bc9