Zobrazeno 1 - 10
of 51
pro vyhledávání: '"Mathias, Beller"'
Autor:
Pamela E. Molinari, Adriana R. Krapp, Andrea Weiner, Hannes M. Beyer, Arun Kumar Kondadi, Tim Blomeier, Melina López, Pilar Bustos-Sanmamed, Evelyn Tevere, Wilfried Weber, Andreas S. Reichert, Nora B. Calcaterra, Mathias Beller, Nestor Carrillo, Matias D. Zurbriggen
Publikováno v:
Nature Communications, Vol 14, Iss 1, Pp 1-18 (2023)
Abstract NADP(H) is a central metabolic hub providing reducing equivalents to multiple biosynthetic, regulatory and antioxidative pathways in all living organisms. While biosensors are available to determine NADP+ or NADPH levels in vivo, no probe ex
Externí odkaz:
https://doaj.org/article/b1ef3a8f51134470b32d0beb2347929b
Autor:
Annika Zink, Undine Haferkamp, Annika Wittich, Mathias Beller, Ole Pless, Alessandro Prigione
Publikováno v:
STAR Protocols, Vol 3, Iss 3, Pp 101602- (2022)
Summary: We present a high-content screening (HCS) protocol for quantifying mitochondrial activity in live neural cells from human induced pluripotent stem cells (iPSCs). The assessment is based on mitochondrial membrane potential, which is influence
Externí odkaz:
https://doaj.org/article/8117817c67c5480cacf02a60814bcc2e
Autor:
Selene Lickfett, Carmen Menacho, Annika Zink, Narasimha Swamy Telugu, Mathias Beller, Sebastian Diecke, Sidney Cambridge, Alessandro Prigione
Publikováno v:
STAR Protocols, Vol 3, Iss 3, Pp 101567- (2022)
Summary: We present a high-content analysis (HCA) protocol for monitoring the outgrowth capacity of human neurons derived from induced pluripotent stem cells (iPSCs). We describe steps to perform HCA imaging, followed by quantifying the morphology of
Externí odkaz:
https://doaj.org/article/f1b1ef110cbd49f5820bcac738ab8f4b
Autor:
Jürgen W. Schönborn, Fiona A. Stewart, Kerstin Maas Enriquez, Irfan Akhtar, Andrea Droste, Silvio Waschina, Mathias Beller
Publikováno v:
iScience, Vol 24, Iss 11, Pp 103216- (2021)
Summary: We know a lot about varying gut microbiome compositions. Yet, how the bacteria affect each other remains elusive. In mammals, this is largely based on the sheer complexity of the microbiome with at least hundreds of different species. Thus,
Externí odkaz:
https://doaj.org/article/a3c5a5cc30c1473a97274632eeaa0226
Autor:
Mercedeh Farhat Sabet, Sumanta Barman, Mathias Beller, Sven G. Meuth, Nico Melzer, Orhan Aktas, Norbert Goebels, Tim Prozorovski
Publikováno v:
International Journal of Molecular Sciences, Vol 24, Iss 1, p 248 (2022)
Anti-NMDA receptor (NMDAR) encephalitis is frequently associated with demyelinating disorders (e.g., multiple sclerosis (MS), neuromyelitis optica spectrum disorder (NMOSD), myelin oligodendrocyte glycoprotein-associated disease (MOGAD)) with regard
Externí odkaz:
https://doaj.org/article/631f450135574793972c7e241b1d512b
Autor:
Nina Graffmann, Audrey Ncube, Soraia Martins, Aurelian Robert Fiszl, Philipp Reuther, Martina Bohndorf, Wasco Wruck, Mathias Beller, Constantin Czekelius, James Adjaye
Publikováno v:
Biology Open, Vol 10, Iss 1 (2021)
Non-alcoholic fatty liver disease (NAFLD) is a multifactorial disease. Its development and progression depend on genetically predisposed susceptibility of the patient towards several ‘hits’ that induce fat storage first and later inflammation and
Externí odkaz:
https://doaj.org/article/d195cdd79e2044b5a974b11ba068feb5
Publikováno v:
PLoS ONE, Vol 16, Iss 2, p e0247376 (2021)
All metazoans are colonized by a complex and diverse set of microorganisms. The microbes colonize all parts of the body and are especially abundant in the gastrointestinal tract, where they constitute the gut microbiome. The fruit fly Drosophila mela
Externí odkaz:
https://doaj.org/article/7e95422a908c4d40867dd66091162e01
Autor:
Silvia Maglioni, Nayna Arsalan, Anna Hamacher, Shiwa Afshar, Alfonso Schiavi, Mathias Beller, Natascia Ventura
Publikováno v:
Cells, Vol 11, Iss 1, p 100 (2021)
The aging process is concurrently shaped by genetic and extrinsic factors. In this work, we screened a small library of natural compounds, many of marine origin, to identify novel possible anti-aging interventions in Caenorhabditis elegans, a powerfu
Externí odkaz:
https://doaj.org/article/fd91548b434e4f5ea9ba58a8cf384c13
Autor:
Michael Werthebach, Fiona A. Stewart, Alisa Gahlen, Tabea Mettler-Altmann, Irfan Akhtar, Kerstin Maas-Enriquez, Andrea Droste, Thomas O. Eichmann, Gereon Poschmann, Kai Stühler, Mathias Beller
Publikováno v:
Cell Reports, Vol 26, Iss 13, Pp 3726-3740.e7 (2019)
Summary: Lipid droplets (LDs) are the universal cellular storage organelles for esterified neutral lipids. The increasing number of characterized LD-associated proteins attained LDs with hitherto unexpected functions on top of their classical role as
Externí odkaz:
https://doaj.org/article/359f370bb7f949fca8dc594d84584e7d
Autor:
Kirsten Tschapalda, Ya-Qin Zhang, Li Liu, Kseniya Golovnina, Thomas Schlemper, Thomas O. Eichmann, Madhu Lal-Nag, Urmila Sreenivasan, John McLenithan, Slava Ziegler, Carole Sztalryd, Achim Lass, Douglas Auld, Brian Oliver, Herbert Waldmann, Zhuyin Li, Min Shen, Matthew B. Boxer, Mathias Beller
Publikováno v:
EBioMedicine, Vol 8, Iss C, Pp 49-59 (2016)
Excess lipid storage is an epidemic problem in human populations. Thus, the identification of small molecules to treat or prevent lipid storage-related metabolic complications is of great interest. Here we screened >320.000 compounds for their abilit
Externí odkaz:
https://doaj.org/article/6d353b3c4e674fdc8ba176664da784f4