Zobrazeno 1 - 10
of 22
pro vyhledávání: '"Mathews Valuparampil Varghese"'
Autor:
Olga Rafikova, Joel James, Cody A. Eccles, Sergey Kurdyukov, Maki Niihori, Mathews Valuparampil Varghese, Ruslan Rafikov
Publikováno v:
Biology of Sex Differences, Vol 11, Iss 1, Pp 1-9 (2020)
Abstract Background The mechanisms involved in pulmonary hypertension (PH) development in patients and pre-clinical models are poorly understood. PH has a well-established sex dimorphism in patients with increased frequency of PH in females, and more
Externí odkaz:
https://doaj.org/article/291f43c415554f9aabf17c80db58e337
Autor:
Mathews Valuparampil Varghese, Maki Niihori, Cody A Eccles, Sergey Kurdyukov, Joel James, Olga Rafikova, Ruslan Rafikov
Publikováno v:
Antioxidants, Vol 9, Iss 2, p 104 (2020)
Pulmonary arterial hypertension (PAH) is a chronic cardiopulmonary disorder instigated by pulmonary vascular cell proliferation. Activation of Akt was previously reported to promote vascular remodeling. Also, the irreversible nitration of Y350 residu
Externí odkaz:
https://doaj.org/article/d702ca3aac01466b8f9a01bbcbc6ae70
Publikováno v:
Am J Physiol Lung Cell Mol Physiol
We have previously reported that several patients with idiopathic pulmonary hypertension (PH) had different types of G6PD deficiency. However, the role of G6PD in PH is multifactorial because G6PD is involved in controlling oxidative stress, metaboli
Autor:
Maki Niihori, Natalie K. Barker, Olga Rafikova, Mathews Valuparampil Varghese, Cody A. Eccles, Ruslan Rafikov, Lawrence J. Mandarino, Marina A. Zemskova, Paul R. Langlais, Moulun Luo, Joel James
Publikováno v:
Arteriosclerosis, Thrombosis, and Vascular Biology
Supplemental Digital Content is available in the text.
Objective: NFU1 is a mitochondrial iron-sulfur scaffold protein, involved in iron-sulfur assembly and transfer to complex II and LAS (lipoic acid synthase). Patients with the point mutation
Objective: NFU1 is a mitochondrial iron-sulfur scaffold protein, involved in iron-sulfur assembly and transfer to complex II and LAS (lipoic acid synthase). Patients with the point mutation
Autor:
Joel James, Mathews Valuparampil Varghese, Maki Niihori, Dan Yi, Zhiyu Dai, Olga Rafikova, Ruslan Rafikov
Publikováno v:
The FASEB Journal. 36
Publikováno v:
The FASEB Journal. 36
Autor:
Joel James, Maki Niihori, Nolan McClain, Mathews Valuparampil Varghese, Olga Rafikova, Ruslan Rafikov
Publikováno v:
The FASEB Journal. 36
Autor:
Marina A. Zemskova, Ruslan Rafikov, Anup Srivastava, Mathews Valuparampil Varghese, Cody A. Eccles, Joel James, Olga Rafikova
Publikováno v:
Blood
Several studies demonstrate that hemolysis and free heme in circulation cause endothelial barrier dysfunction and are associated with severe pathological conditions such as acute respiratory distress syndrome, acute chest syndrome, and sepsis. Howeve
Autor:
Anna A. Stepanova, Alexander Galkin, Maki Niihori, Sergey Kurdyukov, Mathews Valuparampil Varghese, Olga Rafikova, Marina A. Zemskova, Cody A. Eccles, Ruslan Rafikov
Publikováno v:
American Journal of Respiratory Cell and Molecular Biology. 62:231-242
NFU1 is a mitochondrial protein that is involved in the biosynthesis of iron-sulfur clusters, and its genetic modification is associated with disorders of mitochondrial energy metabolism. Patients ...