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pro vyhledávání: '"Mathew T. Wright"'
Publikováno v:
Tetrahedron Letters. 51:4150-4152
The synthesis of alkyl-substituted 2-pyrrolecarboxylate esters has been accomplished by the condensation reaction of a symmetrical vinamidinium salt and glycine ester derivatives.
Autor:
Stanton Q. Smith, Rene P.F. Kanters, Benjamin C. Giglio, Peter J. Barelli, Matthew J. Keough, Emily J. Kluball, Mona Hovaizi, Eric F. Worrall, John T. Gupton, Kara L. Finzel, Shane R. Nunes, James E. Eaton, Xin Jia, Jennifer M. Birnstihl, Timothy M. Smith, R. Scott Welden, Nakul Telang, Kayleigh E. Hall, Mathew T. Wright
Studies directed at the amine exchange reaction of vinamidinium salts followed by sodium borohydride reduction to secondary and tertiary allylic amines are described. The tertiary allylic amines were alkylated and subjected to base mediated rearrange
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4f6777fb421a1979c14de522b4f5d3b1
https://europepmc.org/articles/PMC2990967/
https://europepmc.org/articles/PMC2990967/
Publikováno v:
ChemInform. 41
A new route is presented to synthesize pyrrole 2-carboxylates, pharmaceutically important substructures, via cyclocondensation of salts (I) with glycine esters.