Zobrazeno 1 - 10
of 40
pro vyhledávání: '"Mathew Robson"'
Autor:
Mathieu Ferrari, Matteo Righi, Vania Baldan, Patrycja Wawrzyniecka, Anna Bulek, Alexander Kinna, Biao Ma, Reyisa Bughda, Zulaikha Akbar, Saket Srivastava, Isaac Gannon, Mathew Robson, James Sillibourne, Ram Jha, Mohamed El-Kholy, Oliver Muhammad Amin, Evangelia Kokalaki, Mohammed Amin Banani, Rehan Hussain, William Day, Wen Chean Lim, Priyanka Ghongane, Jade R. Hopkins, Dennis Jungherz, Marco Herling, Martin Welin, Sachin Surade, Michael Dyson, John McCafferty, Derek Logan, Shaun Cordoba, Simon Thomas, Andrew Sewell, Paul Maciocia, Shimobi Onuoha, Martin Pule
Publikováno v:
Nature Communications, Vol 15, Iss 1, Pp 1-16 (2024)
Abstract Peripheral T cell lymphomas are typically aggressive with a poor prognosis. Unlike other hematologic malignancies, the lack of target antigens to discriminate healthy from malignant cells limits the efficacy of immunotherapeutic approaches.
Externí odkaz:
https://doaj.org/article/0a0cba1c19b24f4e8e75069f7a2b0924
Autor:
Callum McKenzie, Mohamed El-Kholy, Farhaan Parekh, Mathew Robson, Katarina Lamb, Christopher Allen, James Sillibourne, Shaun Cordoba, Simon Thomas, Martin Pule
Publikováno v:
Molecular Therapy: Nucleic Acids, Vol 32, Iss , Pp 603-621 (2023)
The hostile tumor microenvironment limits the efficacy of adoptive cell therapies. Activation of the Fas death receptor initiates apoptosis and disrupting these receptors could be key to increasing CAR T cell efficacy. We screened a library of Fas-TN
Externí odkaz:
https://doaj.org/article/3161044ecdb64eac92495eea73fe8a62
Autor:
Julia Taylor, Anna Bulek, Isaac Gannon, Mathew Robson, Evangelia Kokalaki, Thomas Grothier, Callum McKenzie, Mohamed El-Kholy, Maria Stavrou, Charlotte Traynor-White, Wen Chean Lim, Panagiota Panagiotou, Saket Srivastava, Vania Baldan, James Sillibourne, Mathieu Ferrari, Martin Pule, Simon Thomas
Publikováno v:
Frontiers in Immunology, Vol 14 (2023)
SHP1 and SHP2 are SH2 domain-containing proteins which have inhibitory phosphatase activity when recruited to phosphorylated ITIMs and ITSMs on inhibitory immune receptors. Consequently, SHP1 and SHP2 are key proteins in the transmission of inhibitor
Externí odkaz:
https://doaj.org/article/e38d52e6c99944609c3459b7f08fd187
Autor:
Evangelia Kokalaki, Biao Ma, Mathieu Ferrari, Thomas Grothier, Warren Hazelton, Somayya Manzoor, Eren Costu, Julia Taylor, Anna Bulek, Saket Srivastava, Isaac Gannon, Ram Jha, Rosalind Gealy, Lukas Stanczuk, Tatiana Rizou, Mathew Robson, Mohamed El-Kholy, Vania Baldan, Matteo Righi, James Sillibourne, Simon Thomas, Shimobi Onuoha, Shaun Cordoba, Martin Pule
Publikováno v:
Molecular Therapy.
Autor:
Thomas A. Brown, Glenn W. Johnson, Courtney D. Sandau, David Megson, Eric J. Reiner, Mathew Robson, Guuske P. Tiktak, Gareth Rhys Jones
Polychlorinated biphenyls (PCBs) can provide crucial information into the bioaccumulation and biomagnification of POPs in marine mammals. Muscle tissue samples were obtained for detailed PCB congener specific analysis of all 209 PCBs in 11 species of
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::419e5a7c01c814f09d67cf6b01a44399
https://e-space.mmu.ac.uk/628696/
https://e-space.mmu.ac.uk/628696/
Autor:
Quentin A. Pankhurst, May Zaw Thin, Matthew Ellis, Fang-Yu Lin, Sergio A. Quezada, Giulia Agliardi, Clare Jones, Mark F. Lythgoe, Kerry A. Chester, Maxim Shevtsov, R. Barbara Pedley, Maha R. A. Abdollah, Thomas Carter, Paul Mulholland, Cordula Gruettner, Paul Southern, Angela Richard-Londt, Tammy L. Kalber, Mathew Robson, V. A. Ryzhov, Rafael Torres Martin de Rosales, Sebastian Brandner
Publikováno v:
Small. 17:2005241
Magnetic hyperthermia (MH) harnesses the heat-releasing properties of superparamagnetic iron oxide nanoparticles (SPIONs) and has potential to stimulate immune activation in the tumor microenvironment whilst sparing surrounding normal tissues. To ass
Autor:
Vessela, Vassileva, Vineeth, Rajkumar, Mario, Mazzantini, Mathew, Robson, Adam, Badar, Surinder, Sharma, Erik, Årstad, Daniel, Hochhauser, Mark F, Lythgoe, Jane, Kinghorn, Geoffrey M, Boxer, Rosmund Barbara, Pedley
Publikováno v:
Journal of Nuclear Medicine. 56:1239-1245
Despite extensive efforts to improve the clinical management of patients with colorectal cancer, approved treatments for advanced disease offer limited survival benefit. Therefore, the identification of novel treatment strategies is essential. We eva
Autor:
Erik Årstad, Adam Badar, Andrew Baxter, John F. Bower, Karl M. Cable, Michael A. Carroll, Melanie Y. T. Chan, Michael Charlton, Martin Christlieb, Bart Cornelissen, Liam R. Cox, Ben Davis, Jonathan R. Dilworth, Ethaar El-Emir, George J. Ellames, Eva Galante, Neil Geach, Antony D. Gee, Véronique Gouverneur, Thomas J. Gregson, David Hendry, Rebekka Hueting, Kamila Hussien, Tenzeela Ilyas, Daniel D. Jenkins, Veerle Kersemans, Eric Knagg, Matthias Koepp, Andrew D. Kohler, Joel A. Krauser, Guillaume G. Launay, William J. S. Lockley, Mark F. Lythgoe, Daniel P. Manthorpe, Andrew McEwen, Ruth J. Muschel, Mark F. Oldfield, Jan Passchier, R. Barbara Pedley, Vineeth Rajkumar, Christopher D. Reed, Mathew Robson, Stephen J. Roe, Jim J. Ryan, Kerstin Sander, Nick Shipley, Sean C. Smart, Neil Smith, Daniel W. Spurr, Keith R. Taylor, Matthew Tredwell, David M. Whitehead, Geoffrey Woolley, Ran Yan
Publikováno v:
Journal of Labelled Compounds and Radiopharmaceuticals. 56:50-63
Autor:
Jean-François Focant, Frank L. Dorman, Karl J. Jobst, Mathew Robson, Eric J. Reiner, David Megson
The field of environmental forensics emerged in the 1980s as a consequence of legislative frameworks enacted to enable parties, either states or individuals, to seek compensation with regard to contamination or injury due to damage to the environment
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::23cfae9ea654855268f4ed6487134c66
https://e-space.mmu.ac.uk/617385/
https://e-space.mmu.ac.uk/617385/
Autor:
Nicholas P. Annear, Margaret Ashcroft, Patrick H. Maxwell, Ethaar El-Emir, Mathew Robson, Thomas Briston, Deepa Shukla, Luke W. Thomas, Oliver Staples, Evon Poon, Maria L. Simões, Barbara Pedley, Jun Yang, Adrian L. Harris, Francesca M. Buffa, Afshan Ahmed
Increased expression of the regulatory subunit of HIFs (HIF-1α or HIF-2α) is associated with metabolic adaptation, angiogenesis, and tumor progression. Understanding how HIFs are regulated is of intense interest. Intriguingly, the molecular mechani
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e12641af90c9d67179621c36e7bb0eea
https://doi.org/10.1172/jci58780
https://doi.org/10.1172/jci58780