Zobrazeno 1 - 10
of 17
pro vyhledávání: '"Mathew P. Dixon"'
Autor:
Linhua Gan, Jingjing Sun, Shuo Yang, Xiaocui Zhang, Wu Chen, Yiyu Sun, Xiaohua Wu, Cheng Cheng, Jing Yuan, Anan Li, Mark A. Corbett, Mathew P. Dixon, Tim Thomas, Anne K. Voss, Jozef Gécz, Guang-Zhong Wang, Azad Bonni, Qian Li, Ju Huang
Publikováno v:
Cell Reports, Vol 30, Iss 11, Pp 3717-3728.e6 (2020)
Summary: Understanding the mechanisms of activity-dependent gene transcription underlying adaptive behaviors is challenging at neuronal-subtype resolution. Using cell-type specific molecular analysis in agouti-related peptide (AgRP) neurons, we revea
Externí odkaz:
https://doaj.org/article/d7c2fa9ecf73464dbbbdbbc44e5eea55
Autor:
Wu Chen, Xiaohua Wu, Jingjing Sun, Anan Li, Azad Bonni, Guang-Zhong Wang, Anne K. Voss, Mathew P. Dixon, Tim Thomas, Shuo Yang, Cheng Cheng, Linhua Gan, Mark A. Corbett, Jing Yuan, Qian Li, Xiaocui Zhang, Ju Huang, Yiyu Sun, Jozef Gecz
Publikováno v:
Cell Reports, Vol 30, Iss 11, Pp 3717-3728.e6 (2020)
Summary: Understanding the mechanisms of activity-dependent gene transcription underlying adaptive behaviors is challenging at neuronal-subtype resolution. Using cell-type specific molecular analysis in agouti-related peptide (AgRP) neurons, we revea
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::19c249df81cb21265f226790a010a8d3
http://www.sciencedirect.com/science/article/pii/S221112472030259X
http://www.sciencedirect.com/science/article/pii/S221112472030259X
Autor:
Andreas Strasser, William Chiang, Brandon J. Aubrey, Antonia N. Policheni, Mathew P. Dixon, Alexandra L. Garnham, Jozef Gecz, Matthew P. McCormack, Anne K. Voss, Axel Kallies, Kevin Man, Yifang Hu, Andrew J. Kueh, Tim Thomas, Stephen Wilcox, Daniel H.D. Gray, Renee Gloury, Tan A. Nguyen, Gordon K. Smyth, Helen M. McRae, Rose E. May, Edwin D. Hawkins, Ladina Di Rago, Bilal N. Sheikh, Matthew T. Witkowski, Warren S. Alexander, Mark A. Corbett
Somatically acquired mutations in PHF6 (plant homeodomain finger 6) frequently occur in hematopoietic malignancies and often coincide with ectopic expression of TLX3. However, there is no functional evidence to demonstrate whether these mutations con
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::95df0fc9d04059dd9be253eb79941150
https://europepmc.org/articles/PMC6695515/
https://europepmc.org/articles/PMC6695515/
Autor:
Didier Devys, Matthieu Stierle, Mathew P. Dixon, Farrah El-Saafin, Laszlo Tora, Luc Negroni, Imre Berger, Jean Marie Garnier, William B. Dobyns, Natalie L. Downer, Anne K. Voss, Tim Thomas, Isabelle Kolb-Cheynel, Cynthia J. Curry, Tao Ye
Publikováno v:
Human Molecular Genetics
Human Molecular Genetics, Oxford University Press (OUP), 2018, 27 (12), pp.2171-2186. ⟨10.1093/hmg/ddy126⟩
El-Saafin, F, Curry, C, Ye, T, Garnier, J M, Kolb-Cheynel, I, Stierle, M, Downer, N L, Dixon, M P, Negroni, L, Berger, I, Thomas, T, Voss, A K, Dobyns, W, Devys, D & Tora, L 2018, ' Homozygous TAF8 mutation in a patient with intellectual disability results in undetectable TAF8 protein, but preserved RNA polymerase II transcription ', Human Molecular Genetics, vol. 27, no. 12, pp. 2171-2186 . https://doi.org/10.1093/hmg/ddy126
Human Molecular Genetics, Oxford University Press (OUP), 2018, 27 (12), pp.2171-2186. ⟨10.1093/hmg/ddy126⟩
El-Saafin, F, Curry, C, Ye, T, Garnier, J M, Kolb-Cheynel, I, Stierle, M, Downer, N L, Dixon, M P, Negroni, L, Berger, I, Thomas, T, Voss, A K, Dobyns, W, Devys, D & Tora, L 2018, ' Homozygous TAF8 mutation in a patient with intellectual disability results in undetectable TAF8 protein, but preserved RNA polymerase II transcription ', Human Molecular Genetics, vol. 27, no. 12, pp. 2171-2186 . https://doi.org/10.1093/hmg/ddy126
The human general transcription factor TFIID is composed of the TATA-binding protein (TBP) and 13 TBP-associated factors (TAFs). In eukaryotic cells, TFIID is thought to nucleate RNA polymerase II (Pol II) preinitiation complex formation on all prote
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::fb7d25e8f8087c6c928433a48e1d6ad4
https://hal.archives-ouvertes.fr/hal-02349579
https://hal.archives-ouvertes.fr/hal-02349579
Autor:
Caitlin Collin, Mathew P. Dixon, Bilal N. Sheikh, Tamara J. McLennan, Tim Thomas, Peter J. Scambler, Hannah K. Vanyai, Anne K. Voss
Publikováno v:
Developmental Cell
Summary DiGeorge syndrome, caused by a 22q11 microdeletion or mutation of the TBX1 gene, varies in severity greatly, even among monozygotic twins. Epigenetic phenomena have been invoked to explain phenotypic differences in individuals of identical ge
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1e93d51f15cbd395eaf9fc5296b2d7be
Publikováno v:
Molecular and Cellular Biology. 31:845-860
We report here that the MYST histone acetyltransferase HBO1 (histone acetyltransferase bound to ORC; MYST2/KAT7) is essential for postgastrulation mammalian development. Lack of HBO1 led to a more than 90% reduction of histone 3 lysine 14 (H3K14) ace
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f59f508b3d06337a51b5597886423a9a
https://doi.org/10.1128/mcb.00159-10
https://doi.org/10.1128/mcb.00159-10
Publikováno v:
Molecular and Cellular Biology. 28:5093-5105
Acetylation of histone tails is a hallmark of transcriptionally active chromatin. Mof (males absent on the first; also called MYST1 or KAT8) is a member of the MYST family of histone acetyltransferases and was originally discovered as an essential co
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::eda827e28b0b4eecdb0e578d0816fd14
https://doi.org/10.1128/mcb.02202-07
https://doi.org/10.1128/mcb.02202-07
Autor:
Anne K. Voss, Mathew P. Dixon, Rodney L. Rietze, Perry F. Bartlett, Tobias D. Merson, Caitlin Collin, Tim Thomas
Publikováno v:
The Journal of Neuroscience. 26:11359-11370
The adult mammalian brain maintains populations of neural stem cells within discrete proliferative zones. Understanding of the molecular mechanisms regulating adult neural stem cell function is limited. Here, we show that MYST family histone acetyltr
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8ff928dd60b9a30b0b1779e62b3180a5
https://doi.org/10.1523/jneurosci.2247-06.2006
https://doi.org/10.1523/jneurosci.2247-06.2006
Autor:
Anne K. Voss, Tim Thomas, Mathew P. Dixon, Raffi Gugasyan, Thomas C. Brodnicki, Donald Metcalf, Stephen L. Nutt, Lynn M. Corcoran
Publikováno v:
Genes & Development. 20:1175-1186
Monocytic leukemia zinc finger protein (MOZ), a transcriptional coactivator and member of the MYST family of histone acetyltransferases, is the target of recurrent translocations in acute myeloid leukemia. Since genes associated with translocations i
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1edede119f641b8c1e656dd76b9092c9
https://doi.org/10.1101/gad.1382606
https://doi.org/10.1101/gad.1382606
Autor:
Richard N. Pau, David E. Dunstan, Geoffrey J. Howlett, Barrie E. Davidson, William H. Sawyer, Mathew P. Dixon
Publikováno v:
Journal of Biological Chemistry. 277:23186-23192
TyrR from Escherichia coli regulates the expression of genes for aromatic amino acid uptake and biosynthesis. Its central ATP-hydrolyzing domain is similar to conserved domains of bacterial regulatory proteins that interact with RNA polymerase holoen
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::13d4119ad05e0da091bf09e7852d7a8f
https://doi.org/10.1074/jbc.m112184200
https://doi.org/10.1074/jbc.m112184200