Zobrazeno 1 - 10
of 55
pro vyhledávání: '"Mathew J. Thayer"'
Autor:
Michael B. Heskett, Athanasios E. Vouzas, Leslie G. Smith, Phillip A. Yates, Christopher Boniface, Eric E. Bouhassira, Paul T. Spellman, David M. Gilbert, Mathew J. Thayer
Publikováno v:
Nature Communications, Vol 13, Iss 1, Pp 1-19 (2022)
Heskett et al. describe several members of a class of long non-coding RNAs, known as ASARs, which show distinct epigenetic regulation between subclonal lineages and are essential for normal DNA replication timing and stability of human autosomes.
Externí odkaz:
https://doaj.org/article/4e4cb57c90794f0db665eeb98bc386ca
Publikováno v:
Non-Coding RNA, Vol 7, Iss 4, p 66 (2021)
Long non-coding RNAs (lncRNA) comprise a diverse group of non-protein-coding RNAs >200 bp in length that are involved in various normal cellular processes and disease states, and can affect coding gene expression through mechanisms in cis or in trans
Externí odkaz:
https://doaj.org/article/3acb4effdc524b6385e106585ab565c5
Certain chromosome rearrangements display a significant delay in replication timing that is associated with a delay in mitotic chromosome condensation. Chromosomes with delay in replication timing/delay in mitotic chromosome condensation participate
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::25e433c8decb0c17b265c46e6b7150a5
https://doi.org/10.1158/0008-5472.c.6493737.v1
https://doi.org/10.1158/0008-5472.c.6493737.v1
Supplementary Figure 2 from Ionizing Radiation Induces Frequent Translocations with Delayed Replication and Condensation
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::61c40c28826064cfa46a8d690116618c
https://doi.org/10.1158/0008-5472.22363503
https://doi.org/10.1158/0008-5472.22363503
Supplementary Figure 1 from Ionizing Radiation Induces Frequent Translocations with Delayed Replication and Condensation
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b8cec222c401217312f475ef1671cb92
https://doi.org/10.1158/0008-5472.22363506.v1
https://doi.org/10.1158/0008-5472.22363506.v1
Supplementary Figure 4 from Ionizing Radiation Induces Frequent Translocations with Delayed Replication and Condensation
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4ac934c56c562e1b19eab15562d7dc34
https://doi.org/10.1158/0008-5472.22363497
https://doi.org/10.1158/0008-5472.22363497
Supplementary Figure 3 from Ionizing Radiation Induces Frequent Translocations with Delayed Replication and Condensation
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7c2050a10e3caf7d17b010d06c417198
https://doi.org/10.1158/0008-5472.22363500
https://doi.org/10.1158/0008-5472.22363500
ASARs are a family of very-long noncoding RNAs that control replication timing on individual human autosomes, and are essential for chromosome stability. The eight known ASAR genes express RNAs that remain closely associated with their parent chromos
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::1f407cab2b63ab7f2f19b22d80036fa7
https://doi.org/10.1101/2022.06.04.494840
https://doi.org/10.1101/2022.06.04.494840
Autor:
Michael B. Heskett, Athanasios E. Vouzas, Leslie G. Smith, Phillip A. Yates, Christopher Boniface, Eric E. Bouhassira, Paul Spellman, David M. Gilbert, Mathew J. Thayer
ASARs are long noncoding RNA genes that control replication timing of entire human chromosomes in cis. The three known ASAR genes are located on human chromosomes 6 and 15, and are essential for chromosome integrity. To identify ASARs on all human ch
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::5b9313c521b150845bc3aa8664ba9c39
https://doi.org/10.1101/2022.04.25.489405
https://doi.org/10.1101/2022.04.25.489405
Publikováno v:
PLoS Genetics, Vol 11, Iss 1, p e1004923 (2015)
DNA replication initiates at multiple sites along each mammalian chromosome at different times during each S phase, following a temporal replication program. We have used a Cre/loxP-based strategy to identify cis-acting elements that control this rep
Externí odkaz:
https://doaj.org/article/132811f52c7b49dfb1a13f157c3f05e5