Zobrazeno 1 - 3
of 3
pro vyhledávání: '"Mathew J. Rumizen"'
Autor:
Paul G. Richardson, Ann M. Clark, Ki Hyun Kim, Klaus Podar, Weihua Song, Mathew J. Rumizen, Janet Ogden, Mariateresa Fulciniti, Sun-Young Kong, Kenneth C. Anderson, Andreas Goutopoulos, Sabikun Nahar, Peter C. Burger, Teru Hideshima, Yu-Tzu Tai, Xian-Feng Li, Nikhil C. Munshi, Dharminder Chauhan, Luca Rastelli
Publikováno v:
British Journal of Haematology. 149:537-549
This study investigated the cytotoxicity and mechanism of action of AS703026, a novel, selective, orally bioavailable MEK1/2 inhibitor, in human multiple myeloma (MM). AS703026 inhibited growth and survival of MM cells and cytokine-induced osteoclast
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::cd7a7e0c2ff90bb77a0a4c44f979a7ee
https://doi.org/10.1111/j.1365-2141.2010.08127.x
https://doi.org/10.1111/j.1365-2141.2010.08127.x
Autor:
Ann M. Clark, Dharminder Chauhan, Weihua Song, Peter C. Burger, Sabikun Nahar, Robert L. Schlossman, Goutopoulos Andreas, Paul G. Richardson, Kihyun Kim, Klaus Podar, Yu-Tzu Tai, Kenneth C. Anderson, Janet Ogden, Xian-Feng Li, Mariateresa Fulciniti, Teru Hideshima, Nikhil C. Munshi, Mathew J. Rumizen, Luca Rastelli
Publikováno v:
Blood. 114:3848-3848
Abstract 3848 Poster Board III-784 The mitogen-activated protein kinase (MEK)/extracellular signal-regulated kinase (ERK) signaling pathway plays a crucial role in the pathogenesis of human multiple myeloma (MM) by promoting interactions of MM cells
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::8f613f4f428b909402bc6e8f9881b75d
https://doi.org/10.1182/blood.v114.22.3848.3848
https://doi.org/10.1182/blood.v114.22.3848.3848
Autor:
Yu-Tzu Tai, Ender Soydan, Mariateresa Fulciniti, Weihua Song, Xian-Feng Li, Peter Burger, Fangxin Hong, Giovanni Tonon, Kihyun Kim, Mathew J. Rumizen, Sabikun Nahar, Klaus Podar, Dharminder Chauhan, Teru Hideshima, Daniel R. Carrasco, Nikhil C Munshi, Daniel Afar, Kenneth C. Anderson
Publikováno v:
Blood. 112:840-840
Cell membrane protein CS1 is highly expressed by tumor cells from the majority of multiple myeloma (MM) patients (>95%) regardless of cytogenetic abnormalities and response to current treatments. Furthermore, CS1 is detected in MM patient sera and co
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::123066c1b2c3b7a4edf63fd19c61e580
https://doi.org/10.1182/blood.v112.11.840.840
https://doi.org/10.1182/blood.v112.11.840.840