Zobrazeno 1 - 10
of 1 058
pro vyhledávání: '"Mathew H"'
Autor:
Matthew J. Broadhead, Ani Ayvazian-Hancock, Katherine Doucet, Owen Kantelberg, Lesley Motherwell, Fei Zhu, Seth G. N. Grant, Mathew H. Horrocks, Gareth B. Miles
Publikováno v:
Frontiers in Molecular Neuroscience, Vol 16 (2023)
Amyotrophic Lateral Sclerosis (ALS) is characterised by a loss of motor neurons in the brain and spinal cord that is preceded by early-stage changes in synapses that may be associated with TAR-DNA-Binding Protein 43 (TDP-43) pathology. Cellular inclu
Externí odkaz:
https://doaj.org/article/e5081c3854aa45ba9122fdc83da492db
Autor:
Samuel B Pattle, Judi O'Shaughnessy, Owen Kantelberg, Olivia M Rifai, Judith Pate, Kristine Nellany, Nadine Hays, Mark J Arends, Mathew H Horrocks, Fergal M Waldron, Jenna M Gregory
Publikováno v:
The Journal of Pathology: Clinical Research, Vol 9, Iss 1, Pp 44-55 (2023)
Abstract Neurodegenerative diseases such as Parkinson's disease (PD), Alzheimer's disease (AD), and amyotrophic lateral sclerosis (ALS) are traditionally considered strictly neurological disorders. However, clinical presentation is not restricted to
Externí odkaz:
https://doaj.org/article/c5efc50753334660a96f553350f6b2fe
Autor:
Gurvir S. Virdi, Minee L. Choi, James R. Evans, Zhi Yao, Dilan Athauda, Stephanie Strohbuecker, Raja S. Nirujogi, Anna I. Wernick, Noelia Pelegrina-Hidalgo, Craig Leighton, Rebecca S. Saleeb, Olga Kopach, Haya Alrashidi, Daniela Melandri, Jimena Perez-Lloret, Plamena R. Angelova, Sergiy Sylantyev, Simon Eaton, Simon Heales, Dmitri A. Rusakov, Dario R. Alessi, Tilo Kunath, Mathew H. Horrocks, Andrey Y. Abramov, Rickie Patani, Sonia Gandhi
Publikováno v:
npj Parkinson's Disease, Vol 8, Iss 1, Pp 1-22 (2022)
Abstract Mutations in the SNCA gene cause autosomal dominant Parkinson’s disease (PD), with loss of dopaminergic neurons in the substantia nigra, and aggregation of α-synuclein. The sequence of molecular events that proceed from an SNCA mutation d
Externí odkaz:
https://doaj.org/article/fc1ba7fa6d614cbe962ce2b5a05c4fa6
Publikováno v:
Gateways, Vol 16, Iss 1 (2023)
Academic institutions in the United States have increasingly emphasised Community-Based Global Learning (CBGL) programs within international contexts. These programs are assumed to have positive outcomes, but often lack substantive assessment data to
Externí odkaz:
https://doaj.org/article/b4d56f4c106c4af2b795756562d3420c
Autor:
Elsa Zacco, Owen Kantelberg, Edoardo Milanetti, Alexandros Armaos, Francesco Paolo Panei, Jenna Gregory, Kiani Jeacock, David J. Clarke, Siddharthan Chandran, Giancarlo Ruocco, Stefano Gustincich, Mathew H. Horrocks, Annalisa Pastore, Gian Gaetano Tartaglia
Publikováno v:
Nature Communications, Vol 13, Iss 1, Pp 1-13 (2022)
Here, the authors generated an artificial RNA molecule, or aptamer, specific for the Amyotrophic Lateral Sclerosis protein TDP-43. By interacting avidly with its target, the aptamer can be exploited to track TDP-43 phase transition in vitro and in ce
Externí odkaz:
https://doaj.org/article/313504fc94a146ba963e22a3b9d3a822
Autor:
Mathew H Charles, Karen Fowler-Watt
Publikováno v:
Methodological Innovations, Vol 16 (2023)
Working on a participatory arts project with former child soldiers and young survivors of conflict in Colombia’s indigenous Nasa community led to the development of an alternative to the qualitative interview, which we call ‘story listening ’.
Externí odkaz:
https://doaj.org/article/64eddcba0bef49c698196df620abbe98
Autor:
Ella Lucille Thornton, Sarah Maria Paterson, Zoe Gidden, Mathew H. Horrocks, Nadanai Laohakunakorn, Lynne Regan
Publikováno v:
Frontiers in Bioengineering and Biotechnology, Vol 10 (2022)
We present a new method for the surface capture of proteins in cell-free protein synthesis (CFPS). We demonstrate the spontaneous self-assembly of the protein BslA into functionalizable surfaces on the surface of a CFPS reaction chamber. We show that
Externí odkaz:
https://doaj.org/article/061480238b454a6994a82acf9df22198
Autor:
Jonathan M. Aitken, Mathew H. Evans, Rob Worley, Sarah Edwards, Rui Zhang, Tony Dodd, Lyudmila Mihaylova, Sean R. Anderson
Publikováno v:
IEEE Access, Vol 9, Pp 140173-140198 (2021)
At the present time, water and sewer pipe networks are predominantly inspected manually. In the near future, smart cities will perform intelligent autonomous monitoring of buried pipe networks, using teams of small robots. These robots, equipped with
Externí odkaz:
https://doaj.org/article/84b3efcffda74056adfdb5876712cd46
Autor:
Rasmus S Petersen, Andrea Colins Rodriguez, Mathew H Evans, Dario Campagner, Michaela S E Loft
Publikováno v:
PLoS Computational Biology, Vol 17, Iss 2, p e1008723 (2021)
[This corrects the article DOI: 10.1371/journal.pcbi.1007402.].
Externí odkaz:
https://doaj.org/article/fbfd250d5315458a8f7976fc4b907669
Autor:
Rasmus S Petersen, Andrea Colins Rodriguez, Mathew H Evans, Dario Campagner, Michaela S E Loft
Publikováno v:
PLoS Computational Biology, Vol 16, Iss 1, p e1007402 (2020)
Quantification of behaviour is essential for biology. Since the whisker system is a popular model, it is important to have methods for measuring whisker movements from behaving animals. Here, we developed a high-speed imaging system that measures whi
Externí odkaz:
https://doaj.org/article/53ff7e2303614210ad551069899c3030