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pro vyhledávání: '"Mathew D. Selby"'
Autor:
Emanuel Schenck, Wai L. Liu, Rhys M. Jones, Nick Clarke, Charlotte Alice Louise Lane, Michael Paradowski, Charles E. Mowbray, Michelle Collins, Mathew D. Selby, Andrew Simon Bell, David Howard Williams, Sandra D. Newman, Nigel Alan Swain
Publikováno v:
Bioorganicmedicinal chemistry letters. 21(21)
We describe the development of novel benzimidazoles as small molecule histamine H4 receptor (H4R) antagonists and their profiling in rat early toxicity studies. The discovery and optimisation of a second series of pyrimidine based antagonists is then