Zobrazeno 1 - 10 of 17 pro vyhledávání: '"Mathew D Edwards"'
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Akademický článek
The VIP-VPAC2 neuropeptidergic axis is a cellular pacemaking hub of the suprachiasmatic nucleus circadian circuit
Autor: Andrew P. Patton, Mathew D. Edwards, Nicola J. Smyllie, Ryan Hamnett, Johanna E. Chesham, Marco Brancaccio, Elizabeth S. Maywood, Michael H. Hastings
Publikováno v: Nature Communications, Vol 11, Iss 1, Pp 1-17 (2020)
Circadian activity modulation in the suprachiasmatic nucleus (SCN) is a network-level emergent property that requires neuropeptide VIP signaling, yet the precise cellular mechanisms are unknown. Patton et al. show that cells expressing VIP or its rec
Externí odkaz: https://doaj.org/article/ad309a8df6944f3b8e02686e390f2b1d
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2
Akademický článek
Genetic analysis of circadian responses to low frequency electromagnetic fields in Drosophila melanogaster.
Autor: Giorgio Fedele, Mathew D Edwards, Supriya Bhutani, John M Hares, Manuel Murbach, Edward W Green, Stephane Dissel, Michael H Hastings, Ezio Rosato, Charalambos P Kyriacou
Publikováno v: PLoS Genetics, Vol 10, Iss 12, p e1004804 (2014)
The blue-light sensitive photoreceptor cryptochrome (CRY) may act as a magneto-receptor through formation of radical pairs involving a triad of tryptophans. Previous genetic analyses of behavioral responses of Drosophila to electromagnetic fields usi
Externí odkaz: https://doaj.org/article/f5e421b5af99434280b222d247c90bf9
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3
CRYPTOCHROMES confer robustness, not rhythmicity, to circadian timekeeping
Autor: Aziz Sancar, Michael Vanden Oever, Christopher P. Selby, John S. O’Neill, Rachel S. Edgar, Nathaniel P. Hoyle, Johanna E. Chesham, Estere Seinkmane, Nicolai Peschel, Aiwei Zeng, Kevin A. Feeney, David C S Wong, Robin Fischer, Mathew D. Edwards, Nina M Rzechorzek, Marrit Putker, Ko-Fan Chen
Publikováno v: The EMBO Journal
Circadian rhythms are a pervasive property of mammalian cells, tissues and behaviour, ensuring physiological adaptation to solar time. Models of cellular timekeeping revolve around transcriptional feedback repression, whereby CLOCK and BMAL1 activate
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5ffc9bfd1bbd2795180a44b82da50ccb
http://europepmc.org/articles/PMC8013833
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5
The VIP-VPAC2 neuropeptidergic axis is a cellular pacemaking hub of the suprachiasmatic nucleus circadian circuit
Autor: Johanna E. Chesham, Nicola J. Smyllie, Marco Brancaccio, Mathew D. Edwards, Ryan Hamnett, Andrew P. Patton, Michael H. Hastings, Elizabeth S. Maywood
Publikováno v: Nature Communications
Nature Communications, Vol 11, Iss 1, Pp 1-17 (2020)
The hypothalamic suprachiasmatic nuclei (SCN) are the principal mammalian circadian timekeeper, co-ordinating organism-wide daily and seasonal rhythms. To achieve this, cell-autonomous circadian timing by the ~20,000 SCN cells is welded into a tight
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b88a126f17493edc39d8f87ddf19f122
http://europepmc.org/articles/PMC7341843
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6
CRYPTOCHROMES confer robustness, not rhythmicity, to circadian timekeeping
Autor: Ko-Fan Chen, John S. O’Neill, Aziz Sancar, Nicolai Peschel, Nina M Rzechorzek, Marrit Putker, Robin Fischer, Nathaniel P. Hoyle, Aiwei Zeng, Johanna E. Chesham, Kevin A. Feeney, Estere Seinkmane, Mathew D. Edwards, Christopher P. Selby, David C S Wong
SummaryCircadian (approximately daily) rhythms are a pervasive property of mammalian cells, tissues, and behaviour, ensuring physiological and metabolic adaptation to solar time. Models of daily cellular timekeeping revolve around transcriptional fee
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::1a4a1d387385db7ef4c478c43da6f464
https://doi.org/10.1101/2020.05.14.095968
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7
Circadian rhythms and metabolism: from the brain to the gut and back again
Autor: Fiona C Ritchey, Sridhar R. Vasudevan, Matthew R. Cribbet, Clara Bien Peek, Mathew D. Edwards, Erin Hanlon, Ellen Frank, Ryan W. Logan, Jeremy J. Stubblefield
Publikováno v: Annals of the New York Academy of Sciences. 1385:21-40
This paper focuses on the relationship between the circadian system and glucose metabolism. Research across the translational spectrum confirms the importance of the circadian system for glucose metabolism and offers promising clues as to when and wh
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::45a5f062359e88ca56ba8a3b3c171dea
https://doi.org/10.1111/nyas.13188
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8
Cell-autonomous clock of astrocytes drives circadian behavior in mammals
Autor: Johanna E. Chesham, Andrew P. Patton, Elizabeth S. Maywood, Nicola J. Smyllie, Michael H. Hastings, Marco Brancaccio, Mathew D. Edwards
Astrocytes can drive the master clock in the brain The neurons of the suprachiasmatic nucleus (SCN) of the hypothalamus function as a central circadian clock, coordinating mammalian physiology with the 24-hour light-dark cycle. Brancaccio et al. foun
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::38ee6105a8711189e3cba39a58fc3bcc
http://hdl.handle.net/10044/1/79169
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9
Evaluating the frequency of bacterial co-infections in children recruited into a malaria pathogenesis study in The Gambia, West Africa using molecular methods
Autor: Sarah E. Burr, Michael Walther, Gerard A. J. Morris, Mathew D. Edwards
Publikováno v: Molecular and Cellular Probes. 26:151-158
Systemic bacteraemia has been reported in children with severe Plasmodium falciparum malaria in Sub Saharan Africa, making the identification or exclusion of concurrent infections a prerequisite for adequate treatment and studies of the immune respon
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::cd823344829e67a493cd81630e61962d
https://doi.org/10.1016/j.mcp.2012.04.003
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10
Analysis of core circadian feedback loop in suprachiasmatic nucleus of mCry1-luc transgenic reporter mouse
Autor: Nicola J. Smyllie, Michael H. Hastings, Johanna E. Chesham, Marco Brancaccio, John S. O’Neill, Elizabeth S. Maywood, Hugues Dardente, Jean-Michel Fustin, Gemma F. Codner, David G. Hazlerigg, Lesley F Drynan, Mathew D. Edwards
Publikováno v: Proceedings of the National Academy of Sciences of the United States of America
Proceedings of the National Academy of Sciences of the United States of America, National Academy of Sciences, 2013, 110 (23), pp.9547-9552. ⟨10.1073/pnas.1220894110⟩
Proceedings of the National Academy of Sciences of the United States of America 23 (110), 9547-9552. (2013)
The suprachiasmatic nucleus (SCN) coordinates circadian rhythms that adapt the individual to solar time. SCN pacemaking revolves around feedback loops in which expression of Period ( Per ) and Cryptochrome ( Cry ) genes is periodically suppressed by
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f3a62820526f8f300fba55245b188401
https://hal.archives-ouvertes.fr/hal-01129751
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