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of 6
pro vyhledávání: '"Mathew Chamberlain"'
Autor:
Timothy T. Harden, Karina S. Herlambang, Mathew Chamberlain, Jean-Benoît Lalanne, Christopher D. Wells, Gene-Wei Li, Robert Landick, Ann Hochschild, Jane Kondev, Jeff Gelles
Publikováno v:
Nature Communications, Vol 11, Iss 1, Pp 1-11 (2020)
In the canonical bacterial transcription, both nascent transcript and polymerase dissociate from template DNA. By employing multi-color single-molecule fluorescence imaging, here the authors show that RNA polymerases remain bound to DNA after the tra
Externí odkaz:
https://doaj.org/article/13f680680f904593b7b3498bafa4968b
Autor:
Mathew Chamberlain, Richa Hanamsagar, Robert Marcus, Timothy Reizis, Frank O. Nestle, Emanuele de Rinaldis, Virginia Savova
Publikováno v:
Scientific Reports, Vol 10, Iss 1, Pp 1-15 (2020)
Scientific Reports
Scientific Reports
Establishing clinically relevant single-cell (SC) transcriptomic workflows from cryopreserved tissue is essential to move this emerging immune monitoring technology from the bench to the bedside. Improper sample preparation leads to detrimental casca
Autor:
Gene-Wei Li, Timothy T. Harden, Jeff Gelles, Jean-Benoît Lalanne, Jane Kondev, Ann Hochschild, Mathew Chamberlain, Karina S. Herlambang, Christopher D. Wells, Robert Landick
Publikováno v:
Nature Communications, Vol 11, Iss 1, Pp 1-11 (2020)
Nature Communications
Nature Communications
RNA polymerases (RNAPs) transcribe genes through a cycle of recruitment to promoter DNA, initiation, elongation, and termination. After termination, RNAP is thought to initiate the next round of transcription by detaching from DNA and rebinding a new
Autoimmune diseases are a major cause of mortality1,2. Current treatments often yield severe insult to host tissue. It is hypothesized that improved “precision medicine” therapies will target pathogenic cells selectively and thus reduce or elimin
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9313c8d6c409ecaffa7eda51a12ba52c
https://doi.org/10.21203/rs.3.rs-199733/v1
https://doi.org/10.21203/rs.3.rs-199733/v1
Autor:
Virginia Savova, Mathew Chamberlain, Robert Marcus, Timothy Reizis, Richa Hanamsagar, Emanuele de Rinaldis, Frank O. Nestle
Publikováno v:
Scientific Reports
Scientific Reports, Vol 10, Iss 1, Pp 1-1 (2020)
Scientific Reports, Vol 10, Iss 1, Pp 1-1 (2020)
Establishing clinically relevant single-cell (SC) transcriptomic workflows from cryopreserved tissue is essential to move this emerging immune monitoring technology from the bench to the bedside. Improper sample preparation leads to detrimental casca
Publikováno v:
The Journal of Immunology. 202:131.15-131.15
The field of single cell RNA sequencing (sc-SEQ) has exploded in the past few years. From picking up single cells manually under a microscope, to droplet-based encapsulation of cells using microfluidics – this technology has improved in leaps and b