Zobrazeno 1 - 10
of 135
pro vyhledávání: '"Mathew Blurton Jones"'
Autor:
M. Rezaa Mohammadi, Samuel Mathew Rodriguez, Jennifer Cam Luong, Shiri Li, Rui Cao, Hamad Alshetaiwi, Hien Lau, Hayk Davtyan, Mathew Blurton Jones, Mahtab Jafari, Kai Kessenbrock, S. Armando Villalta, Paul de Vos, Weian Zhao, Jonathan R. T. Lakey
Publikováno v:
Communications Biology, Vol 4, Iss 1, Pp 1-17 (2021)
Mohammadi et al. show that the transplantation of pancreatic islets within mesenchymal-stem cell (MSC) exosome-loaded hybrid alginate microcapsules in diabetic mice lead to diminished immune-based foreign body response and hyperglycemia control. This
Externí odkaz:
https://doaj.org/article/2679dce50030425f97c4feb28fe920b9
Autor:
You Jung Kang, Seung Jae Hyeon, Amanda McQuade, Jiwoon Lim, Seung Hyun Baek, Yen N. Diep, Khanh V. Do, Yeji Jeon, Dong‐Gyu Jo, C. Justin Lee, Mathew Blurton‐Jones, Hoon Ryu, Hansang Cho
Publikováno v:
Advanced Science, Vol 11, Iss 20, Pp n/a-n/a (2024)
Abstract Microglial neuroinflammation appears to be neuroprotective in the early pathological stage, yet neurotoxic, which often precedes neurodegeneration in Alzheimer's disease (AD). However, it remains unclear how the microglial activities transit
Externí odkaz:
https://doaj.org/article/5e189f2581fa4244ab1a0031b7cea481
Publikováno v:
Molecular Neurodegeneration, Vol 18, Iss 1, Pp 1-4 (2023)
Abstract Apolipoprotein E (APOE) is the single greatest genetic risk factor for late onset Alzheimer’s disease (AD). Yet, the cell-specific effects of APOE on microglia function have remained unclear. Fortunately, two comprehensive new studies publ
Externí odkaz:
https://doaj.org/article/da6df28d5f434d6ea1b30a5294b6269e
Autor:
Volha Liaudanskaya, Nicholas J. Fiore, Yang Zhang, Yuka Milton, Marilyn F. Kelly, Marly Coe, Ariana Barreiro, Victoria K. Rose, Matthew R. Shapiro, Adam S. Mullis, Anna Shevzov-Zebrun, Mathew Blurton-Jones, Michael J. Whalen, Aviva J. Symes, Irene Georgakoudi, Thomas J. F. Nieland, David L. Kaplan
Publikováno v:
Cell Death and Disease, Vol 14, Iss 8, Pp 1-15 (2023)
Abstract Traumatic Brain injury-induced disturbances in mitochondrial fission-and-fusion dynamics have been linked to the onset and propagation of neuroinflammation and neurodegeneration. However, cell-type-specific contributions and crosstalk betwee
Externí odkaz:
https://doaj.org/article/c2e87a4a96b24b3fae0b37195524c50d
Autor:
Mathew Blurton-Jones, Brian Spencer, Sara Michael, Nicholas A. Castello, Andranik A. Agazaryan, Joy L. Davis, Franz-Josef Müller, Jeanne F. Loring, Eliezer Masliah, Frank M. LaFerla
Publikováno v:
Stem Cell Research & Therapy, Vol 15, Iss 1, Pp 1-2 (2024)
Externí odkaz:
https://doaj.org/article/a8f7f613f4364215aed3a6cbb63b15c4
Autor:
Jean Paul Chadarevian, Hayk Davtyan, Sonia I. Lombroso, F. Chris Bennett, Mathew Blurton-Jones
Publikováno v:
STAR Protocols, Vol 4, Iss 3, Pp 102490- (2023)
Summary: Chimeric mouse models have recently been developed to study human microglia in vivo. However, widespread engraftment of donor microglia within the adult brain has been challenging. Here, we present a protocol to introduce the G795A point mut
Externí odkaz:
https://doaj.org/article/ab58724d49b040f8b0f8e037c243fe92
Autor:
Zhenqing Liu, Jianfei Chao, Cheng Wang, Guihua Sun, Daniel Roeth, Wei Liu, Xianwei Chen, Li Li, E Tian, Lizhao Feng, Hayk Davtyan, Mathew Blurton-Jones, Markus Kalkum, Yanhong Shi
Publikováno v:
Cell Reports, Vol 42, Iss 8, Pp 112841- (2023)
Summary: The C allele of rs11136000 variant in the clusterin (CLU) gene represents the third strongest known genetic risk factor for late-onset Alzheimer’s disease. However, whether this single-nucleotide polymorphism (SNP) is functional and what t
Externí odkaz:
https://doaj.org/article/77cf8d20e7704cc4ab9715b8179a709d
Autor:
Ileana Lorenzini, Eric Alsop, Jennifer Levy, Lauren M. Gittings, Deepti Lall, Benjamin E. Rabichow, Stephen Moore, Ryan Pevey, Lynette M. Bustos, Camelia Burciu, Divya Bhatia, Mo Singer, Justin Saul, Amanda McQuade, Makis Tzioras, Thomas A. Mota, Amber Logemann, Jamie Rose, Sandra Almeida, Fen-Biao Gao, Michael Marks, Christopher J. Donnelly, Elizabeth Hutchins, Shu-Ting Hung, Justin Ichida, Robert Bowser, Tara Spires-Jones, Mathew Blurton-Jones, Tania F. Gendron, Robert H. Baloh, Kendall Van Keuren-Jensen, Rita Sattler
Publikováno v:
Frontiers in Cellular Neuroscience, Vol 17 (2023)
While motor and cortical neurons are affected in C9orf72 amyotrophic lateral sclerosis and frontotemporal dementia (ALS/FTD), it remains largely unknown if and how non-neuronal cells induce or exacerbate neuronal damage. We differentiated C9orf72 ALS
Externí odkaz:
https://doaj.org/article/c5861f14d9984d6d91846ead3941a04a
Autor:
Changyoun Kim, Armine Hovakimyan, Karen Zagorski, Tatevik Antonyan, Irina Petrushina, Hayk Davtyan, Gor Chailyan, Jonathan Hasselmann, Michiyo Iba, Anthony Adame, Edward Rockenstein, Marcell Szabo, Mathew Blurton-Jones, David H. Cribbs, Anahit Ghochikyan, Eliezer Masliah, Michael G. Agadjanyan
Publikováno v:
npj Vaccines, Vol 8, Iss 1, Pp 1-2 (2023)
Externí odkaz:
https://doaj.org/article/92d97849f98d4a9a9c4f3f8781ae3d9c
Autor:
Andrea M. Reyes-Ortiz, Edsel M. Abud, Mara S. Burns, Jie Wu, Sarah J. Hernandez, Nicolette McClure, Keona Q. Wang, Corey J. Schulz, Ricardo Miramontes, Alice Lau, Neethu Michael, Emily Miyoshi, David Van Vactor, John C. Reidling, Mathew Blurton-Jones, Vivek Swarup, Wayne W. Poon, Ryan G. Lim, Leslie M. Thompson
Publikováno v:
iScience, Vol 26, Iss 1, Pp 105732- (2023)
Summary: Huntington disease (HD) is a neurodegenerative disorder caused by expanded CAG repeats in the huntingtin gene that alters cellular homeostasis, particularly in the striatum and cortex. Astrocyte signaling that establishes and maintains neuro
Externí odkaz:
https://doaj.org/article/3051cef5c5b24f3ebdab019b1d8be6cf