Zobrazeno 1 - 10
of 10
pro vyhledávání: '"Mathew A. von Wronski"'
Autor:
Frédéric Padilla, Thierry Bettinger, Alexandre Helbert, Mathew A. Von Wronski, Isabelle Tardy, Jean-Louis Mestas, Cyril Lafon, Jean-Marc Hyvelin
Publikováno v:
Ultrasound in Medicine & Biology. 47:3420-3434
Liposome encapsulation of drugs is an interesting approach in cancer therapy to specifically release the encapsulated drug at the desired treatment site. In addition to thermo-, pH-, light-, enzyme- or redox-responsive liposomes, which have had promi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::43242c3d139b15e32de693fc274a31b2
https://doi.org/10.1016/j.ultrasmedbio.2021.07.022
https://doi.org/10.1016/j.ultrasmedbio.2021.07.022
Autor:
Isabelle Tardy, Michel Schneider, Jean Brochot, Sibylle Pochon, Philippe Bussat, Mathew A. Von Wronski, Lisa Passantino, Thierry Bettinger
Publikováno v:
Investigative Radiology. 45:89-95
BR55, an ultrasound contrast agent functionalized with a heterodimer peptide targeting the vascular endothelial growth factor receptor 2 (VEGFR2), was evaluated in vitro and in vivo, demonstrating its potential for specific tumor detection.The target
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7284953634412395870728bed6c8cf4d
https://doi.org/10.1097/rli.0b013e3181c5927c
https://doi.org/10.1097/rli.0b013e3181c5927c
Autor:
Kondareddiar Ramalingam, Natarajan Raju, Nancy J. Bogdan, Steve Eaton, Edmund R. Marinelli, Mathew A. Von Wronski, Thangavel Arunachalam, Sibylle Pochon, Palaniappa Nanjappan, Pillai Radhakrishna, Michael F. Tweedle, Adrian D. Nunn, Feng Yan, Karen E. Linder
Publikováno v:
Journal of Biological Chemistry. 281:5702-5710
Tuftsin, Thr-Lys-Pro-Arg (TKPR), is an immunostimulatory peptide with reported nervous system effects as well. We unexpectedly found that tuftsin and a higher affinity antagonist, TKPPR, bind selectively to neuropilin-1 and block vascular endothelial
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::977067dcc71e035f58e1cf1d8eb2d51b
https://doi.org/10.1074/jbc.m511941200
https://doi.org/10.1074/jbc.m511941200
Autor:
Jean-Marc Hyvelin, Catherine Botteron, Isabelle Tardy, Delphine Colevret, Mathew A. Von Wronski, Thierry Bettinger, Peter Frinking, Philippe Bussat, Adrian D. Nunn, Anne Lassus, François Tranquart, Maria Costa, Patricia Emmel
Publikováno v:
Investigative radiology. 49(4)
The diagnosis of acute coronary syndrome remains challenging especially in patients without clear symptoms or electrocardiographic and/or biomarker features. A hallmark of ischemia/reperfusion is activation of endothelial cells leading to altered exp
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6ba56003eb9bc59399f5055089089bbc
https://pubmed.ncbi.nlm.nih.gov/24442162
https://pubmed.ncbi.nlm.nih.gov/24442162
Publikováno v:
Carcinogenesis. 16:1385-1390
Adducts of O 6 -alkylguanine in DNA that are induced by cytotoxic, carcinogenic or mutagenic alkylating agents can be removed by the DNA repair enzyme O 6 -methylguanineDNA methyltransferase (MGMT). Human tumor cell lines that do not express this enz
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a3c817a0c3552da9024199ea28937cc1
https://doi.org/10.1093/carcin/16.6.1385
https://doi.org/10.1093/carcin/16.6.1385
Autor:
Jean-Yves Chapelon, Cyril Lafon, François Tranquart, Alexandre Helbert, Frederic Padilla, Mathew A. Von Wronski, Jean-Marc Hyvelin, Isabelle Tardy
Publikováno v:
The Journal of the Acoustical Society of America. 138:1797-1797
Propagation through heterogeneous tissues may hamper the ability to correctly focus ultrasound, especially when targeting a tumor for drug delivery applications. To solve this issue, we propose to use ultrasound molecular imaging (USMI) for treatment
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::880d6790555580100f3bea8365625d06
https://doi.org/10.1121/1.4933699
https://doi.org/10.1121/1.4933699
Autor:
Marshall B. Elam, Fayanne E. Thorngate, Henry G. Wilcox, Lauren M. Cagen, Murray Heimberg, Rajendra Raghow, Nicholas O. Davidson, Mathew A. von Wronski, Ken-ichi Hirano
Publikováno v:
Metabolism: clinical and experimental. 47(7)
We have previously shown that chronic insulin treatment of rat hepatocytes increases the fraction of edited apolipoprotein B (apoB) mRNA from approximately 50% to as much as 90%. We have now examined the effect of insulin on apobec-1 mRNA abundance a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::246fc82d95c0748c30ee5fd959983c93
https://pubmed.ncbi.nlm.nih.gov/9667237
https://pubmed.ncbi.nlm.nih.gov/9667237
Autor:
Thomas P. Brent, Linda C. Harris, Carol C. Venable, Sherie R. Howell, Joanna S. Remack, Mathew A. von Wronski
Publikováno v:
Carcinogenesis. 17(2)
Suppressed expression of the DNA repair enzyme O 6 -methylguanine-DNA methyltransferase (MGMT), characterized as the Mer - phenotype, occurs only in malignant or transformed cell lines. To investigate the relationship between the transformation proce
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1355dd66d0e2ea2c431f47a9ccfe467d
https://pubmed.ncbi.nlm.nih.gov/8625442
https://pubmed.ncbi.nlm.nih.gov/8625442
Autor:
Mathew A. von Wronski, Lawrence E. Ostrowski, Darell D. Bigner, Ahmed Rasheed, S. Clifford Schold, Sandra H. Bigner, Sankar Mitra, Thomas P. Brent
Publikováno v:
Carcinogenesis. 12(9)
When animals are treated with carcinogenic agents that alkylate O6-guanine residues, the incidence of tumors in specific tissues often relates inversely to the level of the DNA repair enzyme O6-methylguanine-DNA methyltransferase (MGMT) present in th
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5a7f8e0427fd0404ada7eb57848b9b85
https://pubmed.ncbi.nlm.nih.gov/1893534
https://pubmed.ncbi.nlm.nih.gov/1893534
Publikováno v:
The FASEB Journal. 21:1292-1292
Shraga-Heled et al. reported experimental results in The FASEB Journal indicating that the potency of VEGF121 is enhanced by the coexpression of neuropilin-1 (NP-1) with VEGFR-2 “. . . even though VEGF121 does not bind to neuropilins” (1). Althou
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::efbb6e52a2c00b71e07a62615a9ee200
https://doi.org/10.1096/fj.07-0504ufm
https://doi.org/10.1096/fj.07-0504ufm