Výsledky vyhledávání - "Mathew A. Storey"

Akademický článek

Metagenomic Exploration of the Marine Sponge Mycale hentscheli Uncovers Multiple Polyketide-Producing Bacterial Symbionts

Autor: Mathew A. Storey, Sarah K. Andreassend, Joe Bracegirdle, Alistair Brown, Robert A. Keyzers, David F. Ackerley, Peter T. Northcote, Jeremy G. Owen

Publikováno v: mBio, Vol 11, Iss 2 (2020)

ABSTRACT Marine sponges have been a prolific source of unique bioactive compounds that are presumed to act as a deterrent to predation. Many of these compounds have potential therapeutic applications; however, the lack of efficient and sustainable sy

Externí odkaz: https://doaj.org/article/94c3f8add06a48ba9ee2fb71c7a960c2

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Metagenomic Exploration of the Marine Sponge Mycale hentscheli Uncovers Multiple Polyketide-Producing Bacterial Symbionts

Autor: Alistair S. Brown, Mathew A. Storey, Sarah K. Andreassend, Joe Bracegirdle, Peter T. Northcote, Robert A. Keyzers, David F. Ackerley, Jeremy G. Owen

Publikováno v: mBio, Vol 11, Iss 2 (2020)
mBio, Vol 11, Iss 2, p e02997-19 (2020)

Marine sponges have been a prolific source of unique bioactive compounds that are presumed to act as a deterrent to predation. Many of these compounds have potential therapeutic applications; however, the lack of efficient and sustainable synthetic r

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c85794f6562911742e8b1e3e8bace71b
https://journals.asm.org/doi/10.1128/mBio.02997-19

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The Flavin Reductase MsuE Is a Novel Nitroreductase that Can Efficiently Activate Two Promising Next-Generation Prodrugs for Gene-Directed Enzyme Prodrug Therapy

Autor: Janine N. Copp, Mathew A. Storey, Adam V. Patterson, Jeff B. Smaill, Laura K. Green, David F. Ackerley, Elsie M. Williams

Publikováno v: Cancers, Vol 5, Iss 3, Pp 985-997 (2013)
Cancers; Volume 5; Issue 3; Pages: 985-997
Cancers

Bacterial nitroreductase enzymes that can efficiently catalyse the oxygen-independent reduction of prodrugs originally developed to target tumour hypoxia offer great potential for expanding the therapeutic range of these molecules to aerobic tumour r

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c9ae07846a152e540ff955b7b6ad23eb
http://www.mdpi.com/2072-6694/5/3/985

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