Zobrazeno 1 - 10
of 85
pro vyhledávání: '"Mathew A Harris"'
Autor:
Rozanna Meijboom, Elizabeth N York, Agniete Kampaite, Mathew A Harris, Nicole White, Maria Del C Valdés Hernández, Michael J Thrippleton, N J J MacDougall, Peter Connick, David P J Hunt, Siddharthan Chandran, Adam D Waldman, FutureMS Consortium
Publikováno v:
PLoS ONE, Vol 18, Iss 7, p e0288967 (2023)
Recurrent neuroinflammation in relapsing-remitting MS (RRMS) is thought to lead to neurodegeneration, resulting in progressive disability. Repeated magnetic resonance imaging (MRI) of the brain provides non-invasive measures of atrophy over time, a k
Externí odkaz:
https://doaj.org/article/6cc8fd6d3fbe4e7b8fab8ecb8756eeed
Publikováno v:
Frontiers in Aging Neuroscience, Vol 4 (2012)
Navigation abilities decline with age, partly due to deficits in numerous component processes. Impaired switching between these various processes (i.e. switching navigational strategies) is also likely to contribute to age-related navigational impair
Externí odkaz:
https://doaj.org/article/ec395f52ffc7469ab3ad11b04db09282
Autor:
Mathew A. Harris, Simon R. Cox, Laura de Nooij, Miruna C. Barbu, Mark J. Adams, Xueyi Shen, Ian J. Deary, Stephen M. Lawrie, Andrew M. McIntosh, Heather C. Whalley
Publikováno v:
Translational Psychiatry, Vol 12, Iss 1, Pp 1-9 (2022)
Abstract Depression is assessed in various ways in research, with large population studies often relying on minimal phenotyping. Genetic results suggest clinical diagnoses and self-report measures of depression show some core similarities, but also i
Externí odkaz:
https://doaj.org/article/aab0a5a9ff184c02856fc613af0c3079
Autor:
Daniel L. McCartney, Robert F. Hillary, Eleanor L. S. Conole, Daniel Trejo Banos, Danni A. Gadd, Rosie M. Walker, Cliff Nangle, Robin Flaig, Archie Campbell, Alison D. Murray, Susana Muñoz Maniega, María del C. Valdés-Hernández, Mathew A. Harris, Mark E. Bastin, Joanna M. Wardlaw, Sarah E. Harris, David J. Porteous, Elliot M. Tucker-Drob, Andrew M. McIntosh, Kathryn L. Evans, Ian J. Deary, Simon R. Cox, Matthew R. Robinson, Riccardo E. Marioni
Publikováno v:
Genome Biology, Vol 23, Iss 1, Pp 1-16 (2022)
Abstract Background Blood-based markers of cognitive functioning might provide an accessible way to track neurodegeneration years prior to clinical manifestation of cognitive impairment and dementia. Results Using blood-based epigenome-wide analyses
Externí odkaz:
https://doaj.org/article/3e2cf700f20647cfac7e3fa529222f6d
Autor:
Claire Green, Aleks Stolicyn, Mathew A. Harris, Xueyi Shen, Liana Romaniuk, Miruna C. Barbu, Emma L. Hawkins, Joanna M. Wardlaw, J. Douglas Steele, Gordon D. Waiter, Anca-Larisa Sandu, Archie Campbell, David J. Porteous, Jonathan R. Seckl, Stephen M. Lawrie, Rebecca M. Reynolds, Jonathan Cavanagh, Andrew M. McIntosh, Heather C. Whalley
Publikováno v:
Translational Psychiatry, Vol 11, Iss 1, Pp 1-9 (2021)
Abstract Hypothalamic–pituitary–adrenal (HPA) axis dysregulation has been commonly reported in major depressive disorder (MDD), but with considerable heterogeneity of results; potentially due to the predominant use of acute measures of an inheren
Externí odkaz:
https://doaj.org/article/89b054256ca14047ae3a738743e18a0d
Autor:
Jeanne Leerssen, Tessa F. Blanken, Elena Pozzi, Neda Jahanshad, Lyubomir Aftanas, Ole A. Andreassen, Bernhard T. Baune, Ivan Brack, Angela Carballedo, Christopher R. K. Ching, Udo Dannlowski, Katharina Dohm, Verena Enneking, Elena Filimonova, Stella M. Fingas, Thomas Frodl, Beata R. Godlewska, Janik Goltermann, Ian H. Gotlib, Dominik Grotegerd, Oliver Gruber, Mathew A. Harris, Sean N. Hatton, Emma Hawkins, Ian B. Hickie, Natalia Jaworska, Tilo Kircher, Axel Krug, Jim Lagopoulos, Hannah Lemke, Meng Li, Frank P. MacMaster, Andrew M. McIntosh, Quinn McLellan, Susanne Meinert, Benson Mwangi, Igor Nenadić, Evgeny Osipov, Maria J. Portella, Ronny Redlich, Jonathan Repple, Matthew D. Sacchet, Philipp G. Sämann, Egle Simulionyte, Jair C. Soares, Martin Walter, Norio Watanabe, Heather C. Whalley, Dilara Yüksel, Dick J. Veltman, Paul M. Thompson, Lianne Schmaal, Eus J. W. Van Someren
Publikováno v:
Translational Psychiatry, Vol 10, Iss 1, Pp 1-11 (2020)
Abstract It has been difficult to find robust brain structural correlates of the overall severity of major depressive disorder (MDD). We hypothesized that specific symptoms may better reveal correlates and investigated this for the severity of insomn
Externí odkaz:
https://doaj.org/article/c7b061d06a71468e8ea7de9e0d6bca55
Autor:
Tina Habota, Anca-Larisa Sandu, Gordon D. Waiter, Christopher J. McNeil, J. Douglas Steele, Jennifer A. Macfarlane, Heather C. Whalley, Ruth Valentine, Dawn Younie, Nichola Crouch, Emma L. Hawkins, Yoriko Hirose, Liana Romaniuk, Keith Milburn, Gordon Buchan, Tessa Coupar, Mairi Stirling, Baljit Jagpal, Beverly MacLennan, Lucasz Priba, Mathew A. Harris, Jonathan D. Hafferty, Mark J. Adams, Archie I. Campbell, Donald J. MacIntyre, Alison Pattie, Lee Murphy, Rebecca M. Reynolds, Rebecca Elliot, Ian S. Penton-Voak, Marcus R. Munafò, Kathryn L. Evans, Jonathan R. Seckl, Joanna M. Wardlaw, Stephen M. Lawrie, Christopher S. Haley, David J. Porteous, Ian J. Deary, Alison D. Murray, Andrew M. McIntosh
Publikováno v:
Wellcome Open Research, Vol 4 (2021)
STratifying Resilience and Depression Longitudinally (STRADL) is a population-based study built on the Generation Scotland: Scottish Family Health Study (GS:SFHS) resource. The aim of STRADL is to subtype major depressive disorder (MDD) on the basis
Externí odkaz:
https://doaj.org/article/b5f75fa6696d40beb0cb207d5c9e2363
Autor:
Mathew A. Harris, Simon R. Cox, Laura de Nooij, Miruna C. Barbu, Mark J. Adams, Xueyi Shen, Ian J. Deary, Stephen M. Lawrie, Andrew M. McIntosh, Heather C. Whalley
Publikováno v:
Translational Psychiatry, Vol 12, Iss 1, Pp 1-1 (2022)
Externí odkaz:
https://doaj.org/article/3ec263912b06456d9bb62bb050a38bb0
Autor:
Liu Shi, Colin R. Buchanan, Simon R. Cox, Robert F. Hillary, Riccardo E. Marioni, Archie Campbell, Caroline Hayward, Aleks Stolicyn, Heather C. Whalley, Mathew A. Harris, Jennifer Waymont, Gordon Waiter, Ellen Backhouse, Joanna M. Wardlaw, Douglas Steele, Andrew Mcintosh, Simon Lovestone, Noel J. Buckley, Alejo J. Nevado‐Holgado
Publikováno v:
Alzheimer’s & Dementia: Diagnosis, Assessment & Disease Monitoring, Vol 13, Iss 1, Pp n/a-n/a (2021)
Abstract Introduction This study aims to first discover plasma proteomic biomarkers relating to neurodegeneration (N) and vascular (V) damage in cognitively normal individuals and second to discover proteins mediating sex‐related difference in N an
Externí odkaz:
https://doaj.org/article/dc204ff9c6c74337954d2be2ac597762
Autor:
Laura de Nooij, Mathew A. Harris, Emma L. Hawkins, Toni-Kim Clarke, Xueyi Shen, Stella W. Y. Chan, Tim B. Ziermans, Andrew M. McIntosh, Heather C. Whalley
Publikováno v:
Wellcome Open Research, Vol 4 (2020)
Background: Within young individuals, mood disorder onset may be related to changes in trajectory of brain structure development. To date, however, longitudinal prospective studies remain scarce and show partly contradictory findings, with a lack of
Externí odkaz:
https://doaj.org/article/40a731d996bf4edeac833934a6590fa9