Zobrazeno 1 - 10 of 10 pro vyhledávání: '"Matheus Santos de Sá"'
1
Caffeoylquinic acids from antiplasmodial active extract of Xanthium cavanillesii fruits and their molecular modelling studies
Autor: Alexsandro Branco, Sônia Carine Cova Costa, Miriam Moreira Mussi, Milena Botelho Pereira Soares, Alex Gutterres Taranto, Franco Henrique Andrade Leite, Matheus Santos de Sá
Publikováno v: Natural Product Research. 31:729-733
The antiplasmodial active extract of Xanthium cavanillesii contains 3,4-dicaffeoyl quinic acid (3,4-DCQA), 3,5-dicaffeoyl quinic acid (3,5-DCQA) and 1,3,5-tricaffeoyl quinic acid (1,3,5-TCQA). These results inspired us to investigate the interaction
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::32503406b234c8696d152ac1457764a7
https://doi.org/10.1080/14786419.2016.1219856
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3
Antimalarial Activity of Physalins B, D, F, and G
Autor: Walter Filgueira de Azevedo, Milena Botelho Pereira Soares, Ricardo Ribeiro dos Santos, Ivone Maria Ribeiro, Therezinha C. B. Tomassini, Maria N. de Menezes, Matheus Santos de Sá, Antoniana U. Krettli
Publikováno v: Journal of Natural Products. 74:2269-2272
The antimalarial activities of physalins B, D, F, and G (1-4), isolated from Physalis angulata, were investigated. In silico analysis using the similarity ensemble approach (SEA) database predicted the antimalarial activity of each of these compounds
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::79876492d639be8a41a113f4f9b6c5b5
https://doi.org/10.1021/np200260f
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4
Structure–activity relationships of mononuclear metal–thiosemicarbazone complexes endowed with potent antiplasmodial and antiamoebic activities
Autor: Deepa Bahl, Ana Cristina Lima Leite, Milena Botelho Pereira Soares, Rajendra M. Srivastava, Amir Azam, Fareeda Athar, Diogo Rodrigo Magalhães Moreira, Matheus Santos de Sá
Publikováno v: Bioorganic & Medicinal Chemistry. 18:6857-6864
A useful concept for the rational design of antiparasitic drug candidates is the complexation of bioactive ligands with transition metals. In view of this, an investigation was conducted into a new set of metal complexes as potential antiplasmodium a
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::26ec4387e6b8d07bcb353ebb66fead4e
https://doi.org/10.1016/j.bmc.2010.07.039
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5
In vitropharmacological screening of macrofungi extracts from the Brazilian northeastern region
Autor: Mariano G. Zalis, Milena S. Lima, José Fernando Oliveira Costa, Ricardo Ribeiro-dos-Santos, Fernanda da Purificação Pinto, Fabrício S. Silva, Aristóteles Góes-Neto, Angélica Maria Lucchese, Matheus Santos de Sá, Milena Botelho Pereira Soares
Publikováno v: Pharmaceutical Biology. 47:384-389
Although the use of macrofungi in popular medicine is very common, especially in East Asia, the knowledge about their pharmacological properties is poorly investigated. The aim of this work was to evaluate the pharmacological potential of six species
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::26acfb70d7e4ee103d244f6d0cbb9f37
https://doi.org/10.1080/13880200902755226
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6
Avaliação da atividade imunomoduladora de extratos de peles e glândulas parotóides de anuros do semi-árido brasileiro
Autor: Matheus Santos de Sá, Flora Acuña Juncá, Lain Carlos Pontes de Carvalho, Ricardo dos Santos, Milena Botelho Pereira Soares
Publikováno v: SITIENTIBUS série Ciências Biológicas. 7:410-415
A pele dos anfíbios possui uma variedade de produtos químicos com diversas atividades biológicas. Esses compostos participam dos mecanismos de defesa contra patógenos e substâncias estranhas aos quais os anfíbios são expostos em seu habitat. E
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::bb153f4473e6a1c3fa484bb0aa4345d3
https://doi.org/10.13102/scb8111
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8
Antiparasitic and Immunomodulatory Activities of 1,1-bis(4-Hydroxyphenyl)-2-Phenyl-but-1-ene and Its Protected and Free 2-Ferrocenyl Derivatives
Autor: Marília O. F. Goulart, Milena Botelho Pereira Soares, Elizabeth A. Hillard, Gérard Jaouen, Antônio Euzébio G. Santana, José Fernando Oliveira Costa, Matheus Santos de Sá, Ricardo Ribeiro-dos-Santos, Pascal Pigeon
Publikováno v: Drug Development Research
Drug Development Research, Wiley, 2010, 71 (1, SI), pp.69-75. ⟨10.1002/ddr.20349⟩
International audience; The ferrocenyl diphenol 1 [1,1-bis(4-hydroxyphenyl)-2-ferrocenyl-but-1-ene] displays strong cytotoxic effects against a variety of cancer cells. In the present study we have evaluated the immunomodulatory and antiparasitic act
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f53ef4d55559a0eb710f741da049da01
https://hal.archives-ouvertes.fr/hal-01230392
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9
Early toxicity screening and selection of lead compounds for parasitic diseases
Autor: Ricardo Ribeiro dos Santos, Matheus Santos de Sá, Milena Botelho Pereira Soares, Jose Fernando Oliveira-Costa, Renata Campos Nogueira
Publikováno v: Current drug targets. 10(3)
Despite many advances made in disease mechanisms knowledge and drug discovery and development processes, the election of promising lead compounds continues to be a challenge. Efficient techniques are required for lead selection of hit compounds selec
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::dcc1c1430286c29c73bac7e3c6b81c6b
https://pubmed.ncbi.nlm.nih.gov/19275565
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