Zobrazeno 1 - 10
of 115
pro vyhledávání: '"Matheus Froeyen"'
Autor:
Kanzal Iman, Muhammad Usman Mirza, Fazila Sadia, Matheus Froeyen, John F. Trant, Safee Ullah Chaudhary
Publikováno v:
Viruses, Vol 16, Iss 8, p 1250 (2024)
The emergence of drug-resistance-inducing mutations in Hepatitis C virus (HCV) coupled with genotypic heterogeneity has made targeting NS3/4A serine protease difficult. In this work, we investigated the mutagenic variations in the binding pocket of G
Externí odkaz:
https://doaj.org/article/5012ef92da2b40af9dddc0f0eba8f9f7
Autor:
Shazia Ilyas, Raheela Tabasum, Ali Iftikhar, Mamoona Nazir, Amina Hussain, Aroosha Hussain, Muhammad Sajjad Ali, Farooq Saleem, Uzma Saleem, Matheus Froeyen, Iskandar Abdullah, Muhammad Usman Mirza, Sarfraz Ahmad
Publikováno v:
Scientific Reports, Vol 11, Iss 1, Pp 1-14 (2021)
Abstract Ifosfamide is a widely used chemotherapeutic agent having broad-spectrum efficacy against several tumors. However, nephro, hepato, neuro cardio, and hematological toxicities associated with ifosfamide render its use limited. These side effec
Externí odkaz:
https://doaj.org/article/27c6a089228c42ba9b88e2326f6f79ce
Autor:
Mubarak A. Alamri, Muhammad Tahir ul Qamar, Muhammad Usman Mirza, Safar M. Alqahtani, Matheus Froeyen, Ling-Ling Chen
Publikováno v:
Journal of Pharmaceutical Analysis, Vol 10, Iss 6, Pp 546-559 (2020)
The papain-like protease (PLpro) is vital for the replication of coronaviruses (CoVs), as well as for escaping innate-immune responses of the host. Hence, it has emerged as an attractive antiviral drug-target. In this study, computational approaches
Externí odkaz:
https://doaj.org/article/dc8844a7ba9242308427b479a0f0469c
Autor:
Muhammad Usman Mirza, Matheus Froeyen
Publikováno v:
Journal of Pharmaceutical Analysis, Vol 10, Iss 4, Pp 320-328 (2020)
Recently emerged SARS-CoV-2 caused a major outbreak of coronavirus disease 2019 (COVID-19) and instigated a widespread fear, threatening global health safety. To date, no licensed antiviral drugs or vaccines are available against COVID-19 although se
Externí odkaz:
https://doaj.org/article/ae6869948fe8411686123346823502fd
Autor:
Fareeha Anwar, Uzma Saleem, Atta-Ur Rehman, Bashir Ahmad, Matheus Froeyen, Muhammad Usman Mirza, Lee Yean Kee, Iskandar Abdullah, Sarfraz Ahmad
Publikováno v:
Frontiers in Pharmacology, Vol 12 (2021)
The presented study was designed to probe the toxicity potential of newly identified compound naphthalen-2-yl 3,5-dinitrobenzoate (SF1). Acute, subacute toxicity and teratogenicity studies were performed as per Organization of economic cooperation an
Externí odkaz:
https://doaj.org/article/aa38a13278484fff8aef7aea148cd067
Autor:
Asia Parveen, Muhammad U. Mirza, Michiel Vanmeert, Javed Akhtar, Hina Bashir, Saadullah Khan, Saqib Shehzad, Matheus Froeyen, Wasim Ahmed, Muhammad Ansar, Naveed Wasif
Publikováno v:
Molecular Genetics & Genomic Medicine, Vol 7, Iss 9, Pp n/a-n/a (2019)
Abstract Background Jalili syndrome (JS) is a rare cone‐rod dystrophy (CRD) associated with amelogenesis imperfecta (AI). The first clinical presentation of JS patients was published in 1988 by Jalili and Smith. Pathogenic mutations in the Cyclin a
Externí odkaz:
https://doaj.org/article/e1a097247d1a4d008bace208f92766bf
Autor:
Hafiz Muzzammel Rehman, Muhammad Usman Mirza, Mian Azhar Ahmad, Mahjabeen Saleem, Matheus Froeyen, Sarfraz Ahmad, Roquyya Gul, Huda Ahmed Alghamdi, Muhammad Shahbaz Aslam, Muhammad Sajjad, Munir Ahmad Bhinder
Publikováno v:
Biology, Vol 9, Iss 9, p 296 (2020)
The outbreak of 2019-novel coronavirus (SARS-CoV-2) that causes severe respiratory infection (COVID-19) has spread in China, and the World Health Organization has declared it a pandemic. However, no approved drug or vaccines are available, and treatm
Externí odkaz:
https://doaj.org/article/a57ab276e5c541e1b7a71f28a943dfc0
Autor:
Imran Ali, Hafiz Muzzammel Rehman, Muhammad Usman Mirza, Muhammad Waheed Akhtar, Rehana Asghar, Muhammad Tariq, Rashid Ahmed, Fatima Tanveer, Hina Khalid, Huda Ahmed Alghamdi, Matheus Froeyen
Publikováno v:
Biology, Vol 9, Iss 8, p 214 (2020)
Cellulases are a set of lignocellulolytic enzymes, capable of producing eco-friendly low-cost renewable bioethanol. However, low stability and hydrolytic activity limit their wide-scale applicability at the industrial scale. In this work, we report t
Externí odkaz:
https://doaj.org/article/dfafc87133f7415baddfd39623151a9d
Autor:
Saima Maher, M. Iqbal Choudhary, Farooq Saleem, Saima Rasheed, Imran Waheed, Sobia Ahsan Halim, Muhammad Azeem, Iskandar Bin Abdullah, Matheus Froeyen, Muhammad Usman Mirza, Sarfraz Ahmad
Publikováno v:
Biology, Vol 9, Iss 8, p 197 (2020)
Withania coagulans (W. coagulans) is well-known in herbal medicinal systems for its high biological potential. Different parts of the plant are used against insomnia, liver complications, asthma, and biliousness, as well as it is reported to be sedat
Externí odkaz:
https://doaj.org/article/361c5e5b66fd401dafa424cc636e9ea4
Autor:
Farooq Saleem, Rashad Mehmood, Saima Mehar, Muhammad Tahir Javed Khan, Zaheer-ud-Din Khan, Muhammad Ashraf, Muhammad Sajjad Ali, Iskandar Abdullah, Matheus Froeyen, Muhammad Usman Mirza, Sarfraz Ahmad
Publikováno v:
Antioxidants, Vol 8, Iss 7, p 231 (2019)
Members of genus Pteris have their established role in the traditional herbal medicine system. In the pursuit to identify its biologically active constituents, the specie Pteris cretica L. (P. cretica) was selected for the bioassay-guided isolation.
Externí odkaz:
https://doaj.org/article/f944d702b3b649fbb6d59d23f8b9105b