670 - WNK2 regulates the chondrocyte response to hyperosmotic stress

Autor: Veerabhadraiah, Shivakumar, Matheson, Derek, Honeggar, Matthew, Aslor, Collin, Jurynec, Mick

Publikováno v: In Osteoarthritis and Cartilage April 2024 32 Supplement 1:S461-S461

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PEG-based Changes to β-sheet Protein Conformational and Proteolytic Stability Depend on Conjugation Strategy and Location

Autor: Draper, Steven R. E., Lawrence, Paul B., Billings, Wendy M., Xiao, Qiang, Brown, Nathaniel P., Becar, Natalie A., Matheson, Derek J., Stephens, Andrew R., Price, Joshua L.

The development of chemical strategies for site-specific protein modification now enables researchers to attach polyethylene glycol (PEG) to a protein drug at one or more specific locations (i.e., protein PEGylation). However, aside from avoiding enz

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::776f67372e87c342ed28cde4cbda2d3c
https://europepmc.org/articles/PMC6330093/

Polyethylene Glycol Based Changes to β-Sheet Protein Conformational and Proteolytic Stability Depend on Conjugation Strategy and Location.

Autor: Draper, Steven R. E., Lawrence, Paul B., Billings, Wendy M., Qiang Xiao, Brown, Nathaniel P., Bécar, Natalie A., Matheson, Derek J., Stephens, Andrew R., Price, Joshua L.

Publikováno v: Bioconjugate Chemistry; 10/18/2017, Vol. 28 Issue 10, p2507-2513, 7p

PIEZO1 variants that reduce open channel probability are associated with familial osteoarthritis.

Autor: Jurynec MJ; Department of Orthopaedics, University of Utah, Salt Lake City, UT, 84108.; Department of Human Genetics, University of Utah, Salt Lake City, UT, 84112.; Department of Biomedical Engineering, University of Utah, Salt Lake City, UT, 84112., Nosyreva E; Department of Neuroscience, UT Southwestern Medical Center, Dallas, TX, 75390., Thompson D; Department of Neuroscience, UT Southwestern Medical Center, Dallas, TX, 75390., Munoz C; Department of Neuroscience, UT Southwestern Medical Center, Dallas, TX, 75390., Novak KA; Department of Orthopaedics, University of Utah, Salt Lake City, UT, 84108., Matheson DJ; Department of Orthopaedics, University of Utah, Salt Lake City, UT, 84108., Kazmers NH; Department of Orthopaedics, University of Utah, Salt Lake City, UT, 84108., Syeda R; Department of Neuroscience, UT Southwestern Medical Center, Dallas, TX, 75390.

Publikováno v: MedRxiv : the preprint server for health sciences [medRxiv] 2024 Sep 05. Date of Electronic Publication: 2024 Sep 05.