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The epigenetic regulator RINF (CXXC5) maintains SMAD7 expression in human immature erythroid cells and sustains red blood cell expansion

Autor: Astori, Audrey, Matherat, Gabriel, Munoz, Isabelle, Gautier, Emilie-Fleur, Surdez, Didier, Zermati, Yaël, Verdier, Frédérique, Zaidi, Sakina, Feuillet, Vincent, Kadi, Amir, LAURET, Evelyne, Delattre, Olivier, Lefèvre, Carine, Fontenay, Michaela, Ségal-Bendirdjian, Evelyne, Dusanter-Fourt, Isabelle, Bouscary, Didier, Hermine, Olivier, Mayeux, Patrick, Pendino, Frédéric

Publikováno v: Haematologica
Haematologica, 2020, 107, pp.268-283. ⟨10.3324/haematol.2020.263558⟩
Haematologica, Ferrata Storti Foundation, 2020, pp.0-0. ⟨10.3324/haematol.2020.263558⟩

International audience; The gene CXXC5, encoding a retinoid-inducible nuclear factor (RINF), is located within a region at 5q31.2 commonly deleted in myelodysplastic syndrome and adult acute myeloid leukemia. RINF may act as an epigenetic regulator a

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ffd13090348248542e11820669aabf95
https://hal.archives-ouvertes.fr/hal-03876291

Functional characterization of factor CXXC5 (RINF) in normal and pathological hematopoiesis

Autor: Matherat, Gabriel

Publikováno v: Hématologie. Université Sorbonne Paris Cité, 2018. Français. ⟨NNT : 2018USPCB223⟩

No abstract
Les érythrocytes (globules rouges, GR) transportent le dioxygène (via l’hémoglobine) des poumons aux tissus de l’organisme. Leur production est assurée par des cellules souches hématopoïétiques (CSH), garantes des cellules

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=dedup_wf_001::c578093cfaa07b95a756785a327a31fa
https://tel.archives-ouvertes.fr/tel-02524729/file/va_Matherat_Gabriel.pdf