Pre-clinical properties of the alpha 4 beta 2 nicotinic acetylcholine receptor partial agonists varenicline, cytisine and dianicline translate to clinical efficacy for nicotine dependence

Autor: Rollema, H., Shrikhande, A., Ward, K. M., Tingley, F. D., Coe, J. W., O'Neill, B. T., Tseng, E., Wang, E. Q., Mather, R. J., Hurst, R. S., Williams, K. E., de Vries, M., Cremers, T., Bertrand, S., Bertrand, D.

Publikováno v: British Journal of Pharmacology, 160(2), 334-345. Wiley-Blackwell

Background and purpose: Smoking cessation trials with three high-affinity partial agonists of alpha 4 beta 2 neuronal nicotinic acetylcholine receptors (nAChRs) have demonstrated differences in their clinical efficacy. This work examines the origin o

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=narcis______::d745cdce23ea5bd45bceaad251977202
https://research.rug.nl/en/publications/b275d2a3-081a-48c9-8a2d-bf75fd11520d

Radio Interference from High-Voltage Lines Part I-Statistical Approach.

Autor: Mather, R. J., Bailey, B. M.

Publikováno v: Transactions of the American Institute of Electrical Engineers, Part III: Power Apparatus & Systems; 1961, Vol. 80 Issue 3, p890-894, 5p

Horizontal Bundle Spacers.

Autor: Mather, R. J., Hard, A. R.

Publikováno v: Transactions of the American Institute of Electrical Engineers, Part III: Power Apparatus & Systems; 1958, Vol. 77 Issue 3, p823-830, 8p

Physical Characteristics of Pipe-Type Cable Faults.

Autor: Mather, R. J., Purviance, J. A.

Publikováno v: Transactions of the American Institute of Electrical Engineers, Part III: Power Apparatus & Systems; 1954, Vol. 73 Issue 2, p1184-1191, 8p

Intracellular guanosine-5'-O-(2-thiodiphosphate) alters the dynamics of receptor-mediated responses in bullfrog sympathetic neurons.

Autor: Simmons, M A, Mather, R J

Publikováno v: Molecular Pharmacology; March 1992, Vol. 41 Issue: 3 p527-534, 8p