Zobrazeno 1 - 10
of 157
pro vyhledávání: '"Mathea R. Allansmith"'
Publikováno v:
Acta Ophthalmologica. 66:87-92
The present study investigated the influence of age and gender on the number of IgA- and IgM-containing cells in the lacrimal gland. Tissues were obtained from male and female rats at 0.2 (infant), 0.6 (pre-pubertal), 1.3 (pubertal), 3 (adult), 8 (mi
Autor:
O. G. Gudmundsson, Mathea R. Allansmith, David A. Sullivan, Kurt J. Bloch, Kristrun Olafsdottir, J. Bjornsson
Publikováno v:
Acta Ophthalmologica. 66:490-497
The present study examined the influence of age and gender on T cell populations in the lacrimal gland. Lacrimal (exorbital) glands were obtained from male and female rats at 19 days (pre-puberty), 9 weeks (adult) and 14 months (mid-life) of age and
Autor:
Kurt J. Bloch, Margarita C. Calonge, Mathea R. Allansmith, Toshikazu Saiga, Rebecca M. Briggs, Richard B. Levene
Publikováno v:
Acta Ophthalmologica. 68:470-476
A model of ocular anaphylaxis with distinct early- and late-phase components was studied in actively immunized guinea pigs. Twenty guinea pigs were injected with dinitrophenylated (DNP) bovine gamma globulin emulsified in Freund's complete adjuvant a
Publikováno v:
Acta Ophthalmologica. 65:406-412
We sought to determine the effect on rat conjunctival mast cells of chronic exposure to a degranulating agent. Compound 48/80 (250 micrograms in 10 microliter) was applied daily to the ocular surface of rats for a total of 13 treatments administered
Publikováno v:
Ophthalmic Research. 24:234-242
An active model of ocular anaphylaxis was developed in guinea pigs to evaluate the histopathology of the early (EPR) and late (LPR) phase reaction, focusing on the role of mast cells. Five groups (n = 6) of animals were actively immunized by first in
Publikováno v:
Ophthalmic Research. 24:45-50
Conjunctival tissue of 12 guinea pigs (6 experimental animals, 6 controls) was sensitized with IgG1 (PCA titer 1:2,000) antisera to dinitrophenol carrier and challenged topically with hapten. Periorbital swelling, conjunctival edema and conjunctival
Autor:
Toshikazu Saiga, Mathea R. Allansmith
Publikováno v:
Ophthalmic Research. 23:335-341
Three models of ocular anaphylaxis containing 6 guinea pigs each were used to examine their effect on tear volume. In the first model, IgG1-rich anti-dinitrophenol (DNP) bovine gamma-globulin serum was injected subconjunctivally, and the animals were
Autor:
Sergio Bonini, Massimo G. Bucci, Annagrazia Berruto, Mathea R. Allansmith, Francesco Balsano, Emilio Adriani, Stefano Bonini
Publikováno v:
Journal of Allergy and Clinical Immunology. 86:869-876
Eleven ryegrass-sensitive patients were challenged weekly for 4 weeks with incremental doses of ryegrass allergen applied topically to one eye; a buffer was applied to the other eye. A clinical examination and tear-fluid cytology were performed befor
Publikováno v:
Ophthalmic Research. 22:95-105
A model of topically induced ocular anaphylaxis in guinea pigs was developed. A guinea pig anti-dinitrophenyl (DNP) bovine gamma-globulin antiserum rich in IgG1 antibodies was injected subconjunctivally; various serum dilutions and latent periods wer
Publikováno v:
Ophthalmic Research. 22:209-219
The ocular late-phase reaction (LPR) is a mast cell-dependent, delayed inflammatory reaction developing 4–12 h after the early-phase reaction (EPR). We developed a passive IgGl antibody-dependent guinea pig model that clinically reproduced the biph