Design of high-throughput screening assays and identification of a SUMO1-specific small molecule chemotype targeting the SUMO-interacting motif-binding surface.

Autor: Alontaga AY; †Department of Molecular Medicine, Beckman Research Institute of the City of Hope, Duarte, California 91010, United States., Li Y; †Department of Molecular Medicine, Beckman Research Institute of the City of Hope, Duarte, California 91010, United States., Chen CH; †Department of Molecular Medicine, Beckman Research Institute of the City of Hope, Duarte, California 91010, United States., Ma CT; ‡Conrad Prebys Center for Chemical Genomics, Sanford-Burnham Institute, La Jolla, California 92037, United States., Malany S; §Conrad Prebys Center for Chemical Genomics, Sanford-Burnham Institute at Lake Nona, Orlando, Florida 32827, United States., Key DE; §Conrad Prebys Center for Chemical Genomics, Sanford-Burnham Institute at Lake Nona, Orlando, Florida 32827, United States., Sergienko E; ‡Conrad Prebys Center for Chemical Genomics, Sanford-Burnham Institute, La Jolla, California 92037, United States., Sun Q; ‡Conrad Prebys Center for Chemical Genomics, Sanford-Burnham Institute, La Jolla, California 92037, United States., Whipple DA; ∥University of Kansas Specialized Chemistry Center, Lawrence, Kansas 66049, United States., Matharu DS; ∥University of Kansas Specialized Chemistry Center, Lawrence, Kansas 66049, United States., Li B; †Department of Molecular Medicine, Beckman Research Institute of the City of Hope, Duarte, California 91010, United States., Vega R; †Department of Molecular Medicine, Beckman Research Institute of the City of Hope, Duarte, California 91010, United States., Li YJ; †Department of Molecular Medicine, Beckman Research Institute of the City of Hope, Duarte, California 91010, United States., Schoenen FJ; ∥University of Kansas Specialized Chemistry Center, Lawrence, Kansas 66049, United States., Blagg BS; ∥University of Kansas Specialized Chemistry Center, Lawrence, Kansas 66049, United States., Chung TD; ‡Conrad Prebys Center for Chemical Genomics, Sanford-Burnham Institute, La Jolla, California 92037, United States., Chen Y; †Department of Molecular Medicine, Beckman Research Institute of the City of Hope, Duarte, California 91010, United States.

Publikováno v: ACS combinatorial science [ACS Comb Sci] 2015 Apr 13; Vol. 17 (4), pp. 239-46. Date of Electronic Publication: 2015 Mar 23.

A cell based high-throughput screening approach for the discovery of new inhibitors of respiratory syncytial virus.

Autor: Chung DH; Center for Predictive Medicine for Biodefense and Emerging Infectious Diseases, University of Louisville, Louisville, KY, USA., Moore BP, Matharu DS, Golden JE, Maddox C, Rasmussen L, Sosa MI, Ananthan S, White EL, Jia F, Jonsson CB, Severson WE

Publikováno v: Virology journal [Virol J] 2013 Jan 10; Vol. 10, pp. 19. Date of Electronic Publication: 2013 Jan 10.

High-throughput screening identifies a bisphenol inhibitor of SV40 large T antigen ATPase activity.

Autor: Seguin SP; Department of Biological Sciences, University of Pittsburgh, Pittsburgh, PA, USA., Evans CW, Nebane-Akah M, McKellip S, Ananthan S, Tower NA, Sosa M, Rasmussen L, White EL, Maki BE, Matharu DS, Golden JE, Aubé J, Brodsky JL, Noah JW

Publikováno v: Journal of biomolecular screening [J Biomol Screen] 2012 Feb; Vol. 17 (2), pp. 194-203. Date of Electronic Publication: 2011 Sep 23.

An outstanding catalyst for asymmetric transfer hydrogenation in aqueous solution and formic acid/triethylamine.

Autor: Matharu DS; Asymmetric Catalysis Group, Coventry, UK CV4 7AL., Morris DJ, Clarkson GJ, Wills M

Publikováno v: Chemical communications (Cambridge, England) [Chem Commun (Camb)] 2006 Aug 14 (30), pp. 3232-4. Date of Electronic Publication: 2006 Jun 23.