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of 8
pro vyhledávání: '"Mathanraj Packiam"'
Autor:
Belinda M. Jackson-Thompson, Marina Torrero, Blima K. Mitre, James Long, Mathanraj Packiam, Edward Mitre
Publikováno v:
Journal of Translational Autoimmunity, Vol 3, Iss , Pp 100065- (2020)
Studies in humans and animals have demonstrated that infection with helminths (parasitic worms) is protective against a range of hyperinflammatory diseases. A number of factors limit translation into clinical use, including: potential contamination o
Externí odkaz:
https://doaj.org/article/3509245bd9b1458194e01800732904ad
Autor:
George Liechti, Erkin Kuru, Mathanraj Packiam, Yen-Pang Hsu, Srinivas Tekkam, Edward Hall, Jonathan T Rittichier, Michael VanNieuwenhze, Yves V Brun, Anthony T Maurelli
Publikováno v:
PLoS Pathogens, Vol 12, Iss 5, p e1005590 (2016)
The peptidoglycan (PG) cell wall is a peptide cross-linked glycan polymer essential for bacterial division and maintenance of cell shape and hydrostatic pressure. Bacteria in the Chlamydiales were long thought to lack PG until recent advances in PG l
Externí odkaz:
https://doaj.org/article/3085056a71704f58a5dc2f5e58448342
Publikováno v:
Proceedings of the National Academy of Sciences. 112:11660-11665
The "chlamydial anomaly," first coined by James Moulder, describes the inability of researchers to detect or purify peptidoglycan (PG) from pathogenic Chlamydiae despite genetic and biochemical evidence and antibiotic susceptibility data that suggest
Autor:
Russell W. Carlson, Mathanraj Packiam, Gregory D. Sempowski, Afrin A. Begum, Melissa S. Ventevogel, Jhuma Ganguly, R. D. Yedery, William M. Shafer, Ann E. Jerse
Publikováno v:
Infection and Immunity. 82:2170-2179
The induction of an intense inflammatory response by Neisseria gonorrhoeae and the persistence of this pathogen in the presence of innate effectors is a fascinating aspect of gonorrhea. Phosphoethanolamine (PEA) decoration of lipid A increases gonoco
Autor:
Yves V. Brun, Erkin Kuru, Jonathan Rittichier, Mathanraj Packiam, George W. Liechti, Yen-Pang Hsu, Srinivas Tekkam, Edward Hall, Michael S. VanNieuwenhze, Anthony T. Maurelli
Publikováno v:
PLoS Pathogens, Vol 12, Iss 5, p e1005590 (2016)
PLoS Pathogens
PLoS Pathogens
The peptidoglycan (PG) cell wall is a peptide cross-linked glycan polymer essential for bacterial division and maintenance of cell shape and hydrostatic pressure. Bacteria in the Chlamydiales were long thought to lack PG until recent advances in PG l
Autor:
Robin R. Ingalls, Hong Wu, Ann E. Jerse, Sandra J. Veit, Nikolaos Mavrogiorgos, Mathanraj Packiam
Publikováno v:
Mucosal immunology
Neisseria gonorrhoeae is a common bacterial sexually transmitted infection. Like all Gram-negative bacteria, the outer membrane of the gonococcus is rich in endotoxin, a known ligand for Toll-like receptor (TLR)4. However, the role of endotoxin and t
Autor:
Shi V. Liu, Richard F. Rest, Dawn M. Shell, David J. McGee, Ranjana Srivastava, Samar Seal, Mathanraj Packiam, Yao-Bin Liu
Publikováno v:
Infection and Immunity. 74:2637-2650
α-2,3-Sialyltransferase (Lst) is expressed on the outer membrane of Neisseria gonorrhoeae and Neisseria meningitidis and sialylates surface lipooligosaccharide (LOS), facilitating resistance to complement-mediated killing. The enzyme is constitutive
Publikováno v:
Frontiers in Microbiology
Frontiers in Cellular and Infection Microbiology, Vol 2 (2011)
Frontiers in Cellular and Infection Microbiology, Vol 2 (2011)
Historically, animal modeling of gonorrhea has been hampered by the exclusive adaptation of Neisseria gonorrhoeae to humans. Genital tract infection can be established in female mice that are treated with 17β-estradiol, however, and many features of