Zobrazeno 1 - 10
of 77
pro vyhledávání: '"Mathangi, Gopalakrishnan"'
Publikováno v:
CPT: Pharmacometrics & Systems Pharmacology, Vol 13, Iss 11, Pp 1939-1952 (2024)
Abstract Opioid use disorders (OUD) are a major issue in the U.S. Current treatments for pregnant women, like methadone and buprenorphine require daily dosing and have adverse effects. Monthly injectable naltrexone (XR‐NTX) mitigates these adverse
Externí odkaz:
https://doaj.org/article/7ef45ee504294c54a3a0c33f6b1733e0
Autor:
Athanasios Chamzas, Eglis Tellez, Andrew SyBing, Jogarao V. S. Gobburu, Mathangi Gopalakrishnan
Publikováno v:
Frontiers in Pharmacology, Vol 15 (2024)
AimTacrolimus, an immunosuppressant used to prevent organ rejection in renal transplant patients, exhibits high inter-patient variability, necessitating therapeutic drug monitoring. Early post-transplant tacrolimus exposure in Hispanics is understudi
Externí odkaz:
https://doaj.org/article/da9ce3aecc11421e8cb3bbd54e1a6cdb
Autor:
Nginache Nampota-Nkomba, Osward M. Nyirenda, Jane Mallewa, Yamikani Chimalizeni, Nettie Dzabala, Michael P. Fay, Mathangi Gopalakrishnan, Matthew B. Laurens, Nicole F. O’Brien, Louis H. Miller, Susan K. Pierce, Brittany A. Riggle, Douglas G. Postels
Publikováno v:
Trials, Vol 25, Iss 1, Pp 1-17 (2024)
Abstract Background Despite treatment with highly effective antimalarial drugs, malaria annually claims the lives of over half a million children under 5-years of age in sub-Saharan Africa. Cerebral malaria (CM), defined as Plasmodium falciparum infe
Externí odkaz:
https://doaj.org/article/db9455a78ade4c80b6bcd3739bf6018c
Publikováno v:
CPT: Pharmacometrics & Systems Pharmacology, Vol 12, Iss 7, Pp 929-940 (2023)
Abstract Taxanes are currently the most frequently used chemotherapeutic agents in cancer care, where real‐world use has focused on minimizing adverse events and standardizing the delivery. Myelosuppression is a well‐characterized, adverse pharma
Externí odkaz:
https://doaj.org/article/6c5ea832dd174276ab984419044f801b
Autor:
Brooke Langevin, Mathangi Gopalakrishnan, Janae Kuttamperoor, John Van Den Anker, Jeanne Murphy, Kathleen F. Arcaro, Dina Daines, Allison C. Sylvetsky
Publikováno v:
Contemporary Clinical Trials Communications, Vol 36, Iss , Pp 101212- (2023)
Introduction: Forty-four percent of lactating women in the United States consume beverages containing low calorie sweeteners (LCS), and the presence of LCS in the food supply has continued to increase in recent years. While LCS are approved by the Un
Externí odkaz:
https://doaj.org/article/ec35809f12ff47c5a4975537c56a6194
Publikováno v:
Clinical and Translational Science, Vol 15, Iss 12, Pp 2878-2887 (2022)
Abstract Randomized, placebo‐controlled trials for binge eating disorder (BED) have revealed highly variable, and often marked, rates of short‐term placebo response. Several quantitative based analyses in patients with BED have inconsistently dem
Externí odkaz:
https://doaj.org/article/92955ec62b284fdb9875437b2ef1d618
Publikováno v:
Pharmaceutics, Vol 15, Iss 10, p 2467 (2023)
A knowledge gap exists in infant tetrahydrocannabinol (THC) data to guide breastfeeding recommendations for mothers who use cannabis. In the present study, a paired lactation and infant physiologically based pharmacokinetic (PBPK) model was developed
Externí odkaz:
https://doaj.org/article/8d390d4631c242c6874bf5c0eb93a276
Autor:
Celine M. Laffont, Eliford Ngaimisi, Mathangi Gopalakrishnan, Vijay Ivaturi, Malcolm Young, Mark K. Greenwald, Christian Heidbreder
Publikováno v:
Frontiers in Pharmacology, Vol 13 (2022)
The severity of the ongoing opioid crisis, recently exacerbated by the COVID-19 pandemic, emphasizes the importance for individuals suffering from opioid use disorder (OUD) to have access to and receive efficacious, evidence-based treatments. Optimal
Externí odkaz:
https://doaj.org/article/f20f95ba52094210b8eddc063199a43d
Autor:
Mathangi Gopalakrishnan, Tiffany Farchione, Mitchell Mathis, Hao Zhu, Mehul Mehta, Ramana Uppoor, Islam Younis
Publikováno v:
Psychiatric Research and Clinical Practice, Vol 3, Iss 1, Pp 38-45 (2021)
Objective To evaluate the performance of the individual Positive and Negative Symptom Scale (PANSS) items, and to assess the feasibility of using a shortened version of the PANSS as an alternative regulatory endpoint for evaluating the efficacy of dr
Externí odkaz:
https://doaj.org/article/53a5f11ac7b84af498eaab89bca9de76
Autor:
Shamir N. Kalaria, Michael Armahizer, Paul McCarthy, Neeraj Badjatia, Jogarao V. Gobburu, Mathangi Gopalakrishnan
Publikováno v:
Clinical and Translational Science, Vol 13, Iss 5, Pp 950-959 (2020)
Limited data exist on the effect of continuous renal replacement therapy (CRRT) methods on anti‐epileptic drug pharmacokinetics (PK). This prospective practice‐based PK study aims to assess the impact of continuous venovenous hemofiltration (CVVH
Externí odkaz:
https://doaj.org/article/79cec51890134bd08ed8766a9d156955