Zobrazeno 1 - 10
of 11
pro vyhledávání: '"Matevž Luštrik"'
Publikováno v:
Powder Technology. 330:114-124
Objective The main objective of the study was to evaluate the influence of a novel modification of the Wurster draft tube on the particle coating performance. Modification embodies enabling of the additional radial flow of pressurized air through the
Publikováno v:
International Journal of Pharmaceutics. 533:377-382
A fast method for pellet coating uniformity analysis, using a commercial computer scanner was developed. The analysis of the individual particle coating thicknesses was based on using a transparent orange colored coating layer deposited on white pell
Autor:
Mirjana Gašperlin, Alenka Zvonar Pobirk, Franc Vrecer, Vesna Pirnat, Jelena Mandić, Matevž Luštrik, Ilija Ilić
Publikováno v:
International journal of pharmaceutics. 583
Solidification of self-microemulsifying drug delivery systems (SMEDDS) is a rising experimental field with important potential for pharmaceutical industry, however fluid-bed granulation with SMEDDS is yet an unexplored solidification technique. The a
Publikováno v:
International journal of pharmaceutics. 566
Self-(micro)emulsifying drug delivery systems (S(M)EDDS) have emerged as effective vehicles for enhancing bioavailability of poorly water soluble drugs, however solidification of the systems represents a major challenge. Objective of this study was d
Autor:
Luca Casula, Aleš Lapanje, Tomaž Rijavec, Špela Zupančič, Anna Maria Fadda, Julijana Kristl, Matevž Luštrik, Petra Kocbek
Publikováno v:
Journal of Controlled Release
Periodontal disease is a widespread chronic condition associated with degradation of periodontal tissues that requires more effective approaches for its treatment. Thus, the aim was to develop a nanodelivery system for local application of antimicrob
Publikováno v:
International journal of pharmaceutics. 549(1-2)
The purpose of the study was to develop a redispersible dry emulsion, containing a lipophilic, poorly water soluble model drug simvastatin, by employing fluid bed coating technology. The presented dry emulsion manufacturing approach produces pellets
Publikováno v:
European Journal of Pharmaceutical Sciences. 75:114-122
Mini-tablets are gaining great attention as systems capable of being formulated into multiple unit systems providing a specific drug release pattern. Within the presented research a combined, multiple-unit system, based on different coated matrix min
Publikováno v:
Powder Technology. 235:640-651
The main objective of this study was to develop a piezoelectric probe for measuring the impact rate of particles to enable characterization of the shape of particle number density profiles and characteristic particle impact frequencies inside the dra
Publikováno v:
Drug development and industrial pharmacy. 38(4)
In this study, different modifications of bottom spray fluid-bed coater with draft tube inserted were characterized and evaluated.After coating the neutral pellets with polymeric solution comprising coloring agent pellet batches were characterized fo
Publikováno v:
Pharmaceutical development and technology. 17(3)
This study evaluated the performance of two bottom-spray coaters and the effect of pellet-size variability on coating uniformity. A conventional Wurster chamber was used for the first group of trials, and a Wurster chamber with a novel swirl-flow gen