Zobrazeno 1 - 10
of 14
pro vyhledávání: '"Mateusz S, Wietecha"'
Autor:
Mateusz S. Wietecha, Marco Pensalfini, Michael Cangkrama, Bettina Müller, Juyoung Jin, Jürgen Brinckmann, Edoardo Mazza, Sabine Werner
Publikováno v:
Nature Communications, Vol 11, Iss 1, Pp 1-20 (2020)
The relationship between histopathology, gene expression, and biochemical and mechanical properties of wounds is largely unknown. Here, the authors show that activin A alters wound healing at multiple levels by promoting pro-fibrotic gene expression
Externí odkaz:
https://doaj.org/article/2e66745780404598b2279a929056766b
Autor:
Mateusz S. Wietecha, David Lauenstein, Michael Cangkrama, Sybille Seiler, Juyoung Jin, Andreas Goppelt, Manfred Claassen, Mitchell P. Levesque, Reinhard Dummer, Sabine Werner
Publikováno v:
Matrix Biology, 119
Healing wounds and cancers present remarkable cellular and molecular parallels, but the specific roles of the healing phases are largely unknown. We developed a bioinformatics pipeline to identify genes and pathways that define distinct phases across
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4176bf0c273fa02d39c8c02f75c9c7f0
https://doi.org/10.1016/j.matbio.2023.03.003
https://doi.org/10.1016/j.matbio.2023.03.003
Publikováno v:
Trends in Molecular Medicine. 26:1107-1117
Wound repair is a highly regulated process that requires the interaction of various cell types. It has been shown that cancers use the mechanisms of wound healing to promote their own growth. Therefore, it is of importance to identify common regulato
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6000422f29da0c2b5c2c09d02626256c
https://doi.org/10.1016/j.molmed.2020.07.009
https://doi.org/10.1016/j.molmed.2020.07.009
Autor:
Daniel Razansky, Sabine Werner, Maya Ben-Yehuda Greenwald, Mateusz S. Wietecha, Johannes Rebling
Publikováno v:
Advanced Science, Vol 8, Iss 13, Pp n/a-n/a (2021)
Advanced Science
Advanced Science, 8 (13)
Advanced Science
Advanced Science, 8 (13)
Wound healing is a well‐coordinated process, necessitating efficient formation of new blood vessels. Vascularization defects are therefore a major risk factor for chronic, non‐healing wounds. The dynamics of mammalian tissue revascularization, ve
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f546387110f13586a9bd87b36f9be23d
https://www.zora.uzh.ch/id/eprint/216021/
https://www.zora.uzh.ch/id/eprint/216021/
Autor:
Edoardo Mazza, Marco Pensalfini, Mateusz S. Wietecha, Raoul Hopf, Eric Haertel, Sabine Werner
Publikováno v:
Acta Biomaterialia. 65:226-236
A multiscale mechanics approach to the characterization of murine excisional wounds subjected to uniaxial tensile loading is presented. Local strain analysis at a physiological level of tension uncovers the presence of two distinct regions within the
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::05f8a45fd23db0fc3f7a72f52aeda4b6
https://doi.org/10.1016/j.actbio.2017.10.021
https://doi.org/10.1016/j.actbio.2017.10.021
Autor:
Daniel Razansky, Maya Ben-Yehuda Greenwald, Johannes Rebling, Sabine Werner, Mateusz S. Wietecha
Publikováno v:
Adv Sci (Weinh)
Dynamics of tissue revascularization, vessel maturation and remodeling remain poorly understood due to lack of suitable in vivo imaging tools. The new LSOM method offers a versatile tool for tissue engineering and regenerative medicine by empowering
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f9d7c1c42d900e1eb4b2f19f3f95ff9a
https://doi.org/10.1002/advs.202170078
https://doi.org/10.1002/advs.202170078
Autor:
Mateusz S. Wietecha, Lin Chen, Luisa A. DiPietro, Mateusz J. Król, Peter G.W. Gettins, Elizabeth R. Michalczyk
Publikováno v:
American Journal of Physiology-Heart and Circulatory Physiology. 309:H812-H826
During dermal wound repair, hypoxia-driven proliferation results in dense but highly permeable, disorganized microvascular networks, similar to those in solid tumors. Concurrently, activated dermal fibroblasts generate an angiopermissive, provisional
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2a788164c3fc3bdf0969524f88e36004
https://doi.org/10.1152/ajpheart.00153.2015
https://doi.org/10.1152/ajpheart.00153.2015
Autor:
Jürgen Brinckmann, Michael Cangkrama, Serena Grossi, Dimitris Kletsas, Jörn Dengjel, Paul Hiebert, Mateusz S. Wietecha, Heiko Steenbock, Hans-Dietmar Beer, Eric Haertel, Michael Stumpe, Eleni Mavrogonatou, Peter Angel, Sabine Werner
Publikováno v:
Developmental Cell, 46 (2)
Nrf2 is a key regulator of the antioxidant defense system, and pharmacological Nrf2 activation is a promising strategy for cancer prevention and promotion of tissue repair. Here we show, however, that activation of Nrf2 in fibroblasts induces cellula
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::615a345f8d83557cbe78ce36f7a4fbee
https://pubmed.ncbi.nlm.nih.gov/30016619
https://pubmed.ncbi.nlm.nih.gov/30016619
Publikováno v:
Journal of Dental Education. 78:334-348
This study aimed to provide a first nationwide assessment of dental students' attitudes toward the importance of research and its integration into the dental curriculum. For this purpose, the American Association for Dental Research National Student
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::1b5b4596f4aa1ce71788b697e7e99fe2
https://doi.org/10.1002/j.0022-0337.2014.78.3.tb05684.x
https://doi.org/10.1002/j.0022-0337.2014.78.3.tb05684.x
Autor:
Dilara Sahin, Valerie C Amann, Katharina Birkner, Michael Cangkrama, Reinhard Dummer, Sabine Werner, Mateusz S. Wietecha, Mitchell P. Levesque, Daniel Hohl, Aleksandra Piwko-Czuchra, Maria Antsiferova
Publikováno v:
EMBO Molecular Medicine, 9 (1)
EMBO molecular medicine, vol. 9, no. 1, pp. 27-45
EMBO Molecular Medicine
EMBO molecular medicine, vol. 9, no. 1, pp. 27-45
EMBO Molecular Medicine
Activin has emerged as an important player in different types of cancer, but the underlying mechanisms are largely unknown. We show here that activin overexpression is an early event in murine and human skin tumorigenesis. This is functionally import
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ef448a1e0e99e0cd6909b5878316dc88
https://hdl.handle.net/20.500.11850/124243
https://hdl.handle.net/20.500.11850/124243