Zobrazeno 1 - 10
of 28
pro vyhledávání: '"Mateusz Pieróg"'
Autor:
Dorota Nieoczym, Marta Marszalek-Grabska, Radoslaw Szalak, Uday Kundap, Agnieszka A. Kaczor, Tomasz M. Wrobel, Nataliia Kosheva, Malgorzata Komar, Michal Abram, Camila V. Esguerra, Eric Samarut, Mateusz Pieróg, Marcin Jakubiec, Krzysztof Kaminski, Wirginia Kukula-Koch, Kinga Gawel
Publikováno v:
Biomedicine & Pharmacotherapy, Vol 172, Iss , Pp 116234- (2024)
Previously, we demonstrated that palmatine (PALM) – an isoquinoline alkaloid from Berberis sibrica radix, exerted antiseizure activity in the pentylenetetrazole (PTZ)-induced seizure assay in larval zebrafish. The aim of the present study was to mo
Externí odkaz:
https://doaj.org/article/78be2bd0abc84046aa1af304dd7186db
Autor:
Małgorzata Samorek-Pieróg, Tomasz Cencek, Emilia Łabuć, Małgorzata Pac-Sosińska, Mateusz Pieróg, Weronika Korpysa-Dzirba, Aneta Bełcik, Ewa Bilska-Zając, Jacek Karamon
Publikováno v:
Parasites & Vectors, Vol 16, Iss 1, Pp 1-20 (2023)
Abstract Background Eucoleus aerophilus (syn. Capillaria aerophila) is a nematode with a worldwide geographical distribution. It causes a disease called lung capillariosis by affecting the respiratory tract of wild and domestic animals, and has also
Externí odkaz:
https://doaj.org/article/c6356963875c4878a68391ffc586a143
Autor:
Mateusz Pieróg, Katarzyna Socała, Dorota Nieoczym, Elżbieta Wyska, Małgorzata Samorek-Pieróg, Piotr Wlaź
Publikováno v:
Molecules, Vol 28, Iss 9, p 3810 (2023)
In contrast to the other components of the medium-chain triglycerides ketogenic diet (MCT KD), i.e., caprylic acid (CA8), a comprehensive evaluation of caproic (CA6) and lauric acids’ (CA12) properties in standard chemical and electrical seizure te
Externí odkaz:
https://doaj.org/article/865b190ff2b3427693b829fd7330aba0
Autor:
Urszula Doboszewska, Katarzyna Socała, Mateusz Pieróg, Dorota Nieoczym, Jan Sawicki, Adam Sajnóg, Bernadeta Szewczyk, Katarzyna Mlyniec, Ireneusz Sowa, Danuta Barałkiewicz, Piotr Wlaź
Publikováno v:
Cells, Vol 12, Iss 2, p 264 (2023)
The G-protein coupled receptor 39 (GPR39) is gaining increasing attention as a target for future drugs, yet there are gaps in the understanding of its pharmacology. Zinc is an endogenous agonist or an allosteric modulator, while TC-G 1008 is a synthe
Externí odkaz:
https://doaj.org/article/c36f91fdef304a0fb82be45243d9ce0b
Autor:
Urszula Doboszewska, Jan Sawicki, Adam Sajnóg, Aleksandra Szopa, Anna Serefko, Katarzyna Socała, Mateusz Pieróg, Dorota Nieoczym, Katarzyna Mlyniec, Gabriel Nowak, Danuta Barałkiewicz, Ireneusz Sowa, Piotr Wlaź
Publikováno v:
Cells, Vol 11, Iss 13, p 1987 (2022)
Several ligands have been proposed for the GPR39 receptor, including the element zinc. The relationship between GPR39 and magnesium homeostasis has not yet been examined, nor has such a relationship in the context of seizures/epilepsy. We used sample
Externí odkaz:
https://doaj.org/article/20242a421730498b8f200ea8c90c72d7
Publikováno v:
Molecules, Vol 26, Iss 16, p 4841 (2021)
Ellagic acid (EA) is a natural dietary polyphenol that has many beneficial properties, including anti-inflammatory, antioxidant, antiviral, antibacterial, and neuroprotective effects. Studies have revealed that EA may modulate seizure activity in che
Externí odkaz:
https://doaj.org/article/7228f5d331df4b79a82fedb328412274
Autor:
Urszula Doboszewska, Katarzyna Socała, Mateusz Pieróg, Dorota Nieoczym, Jan Sawicki, Małgorzata Szafarz, Kinga Gawel, Anna Rafało-Ulińska, Adam Sajnóg, Elżbieta Wyska, Camila V. Esguerra, Bernadeta Szewczyk, Marzena Maćkowiak, Danuta Barałkiewicz, Katarzyna Mlyniec, Gabriel Nowak, Ireneusz Sowa, Piotr Wlaź
The pharmacological activation of the GPR39 receptor has been proposed as a novel strategy for treating seizures; however, this hypothesis has not been verified experimentally. TC-G 1008 is a small molecule agonist increasingly used to study GPR39 re
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5dda598c23b230d670f39e7c602decfb
https://ruj.uj.edu.pl/xmlui/handle/item/311926
https://ruj.uj.edu.pl/xmlui/handle/item/311926
Autor:
Małgorzata Szafarz, Agnieszka Zelek-Molik, Irena Nalepa, Dorota Nieoczym, Katarzyna Przejczowska-Pomierny, Piotr Wlaź, Elżbieta Wyska, Katarzyna Socała, Mateusz Pieróg
Publikováno v:
Psychopharmacology
Rationale Pterostilbene is the 3,5-dimethoxy derivative of resveratrol with numerous beneficial effects including neuroprotective properties. Experimental studies revealed its anticonvulsant action in the acute seizure tests. Objectives The purpose o
Autor:
Urszula Doboszewska, Katarzyna Socala, Mateusz Pieróg, Dorota Nieoczym, Jan Sawicki, Małgorzata Szafarz, Kinga Gaweł, Anna Rafalo-Ulińska, Adam Sajnóg, Elżbieta Wyska, Camila V. Esguerra, Bernadeta Szewczyk, Marzena Maćkowiak, Danuta Barałkiewicz, Katarzyna Młyniec, Gabriel Nowak, Ireneusz Sowa, Piotr Wlaź
Extracellular/intracellular zinc ions are implicated in processes underlying seizures/epileptogenesis. The G-protein coupled receptor 39 (GPR39) was suggested as a target for extracellular zinc. Activation of GPR39 was proposed as a novel strategy fo
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::81fc3b362fc7467ce8a83eae9e7c912a
https://doi.org/10.21203/rs.3.rs-1182423/v2
https://doi.org/10.21203/rs.3.rs-1182423/v2
Autor:
Piotr Wlaź, Kinga Gawel, Camila V. Esguerra, Katarzyna Socała, Michał Abram, Dorota Nieoczym, Mirosław Zagaja, Bartłomiej Szulczyk, Gniewomir Latacz, Krzysztof Kamiński, Jarogniew J. Łuszczki, Aleksandra Szewczyk, Annamaria Lubelska, Mateusz Pieróg, Marta Andres-Mach, Marcin Jakubiec, Anna Rapacz
Publikováno v:
Neurotherapeutics
In our recent studies, we identified compound N-benzyl-2-(2,5-dioxopyrrolidin-1-yl)propanamide (AS-1) as a broad-spectrum hybrid anticonvulsant which showed potent protection across the most important animal acute seizure models such as the maximal e