Zobrazeno 1 - 10
of 20
pro vyhledávání: '"Mateusz Kaduk"'
Autor:
Sanjana Narang, Mateusz Kaduk, Mark Chernyshev, Gunilla B. Karlsson Hedestam, Martin M. Corcoran
Publikováno v:
Frontiers in Immunology, Vol 14 (2023)
We present a new Rep-Seq analysis tool called corecount, for analyzing genotypic variation in immunoglobulin (IG) and T cell receptor (TCR) genes. corecount is highly efficient at identifying V alleles, including those that are infrequently used in e
Externí odkaz:
https://doaj.org/article/80fd1f4a32f8482ba79d7303a5485e47
Publikováno v:
Frontiers in Immunology, Vol 13 (2022)
The accurate germline gene assignment and assessment of somatic hypermutation in antibodies induced by immunization or infection are important in immunological studies. Here, we illustrate issues specific to the construction of comprehensive immunogl
Externí odkaz:
https://doaj.org/article/d0577b6db0bc4cc491cc09516d87b136
Publikováno v:
Frontiers in Immunology, Vol 12 (2022)
Macaques are frequently used to evaluate candidate vaccines and to study infection-induced antibody responses, requiring an improved understanding of their naïve immunoglobulin (IG) repertoires. Baseline gene usage frequencies contextualize studies
Externí odkaz:
https://doaj.org/article/cfe7e8a20f614397ada45ac3a16d0ea7
Publikováno v:
BMC Bioinformatics, Vol 20, Iss 1, Pp 1-12 (2019)
Abstract Background Orthology inference is normally based on full-length protein sequences. However, most proteins contain independently folding and recurring regions, domains. The domain architecture of a protein is vital for its function, and recom
Externí odkaz:
https://doaj.org/article/3ad95c21edee4cc6a643ca44e5a41f62
Autor:
Néstor Vázquez Bernat, Martin Corcoran, Uta Hardt, Mateusz Kaduk, Ganesh E. Phad, Marcel Martin, Gunilla B. Karlsson Hedestam
Publikováno v:
Frontiers in Immunology, Vol 10 (2019)
Next generation sequencing (NGS) of immunoglobulin (Ig) repertoires (Rep-seq) enables examination of the adaptive immune system at an unprecedented level. Applications include studies of expressed repertoires, gene usage, somatic hypermutation levels
Externí odkaz:
https://doaj.org/article/7a61cba5d1514f6bb3b5837af43eb308
Autor:
Martin Corcoran, Mark Chernyshev, Marco Mandolesi, Sanjana Narang, Mateusz Kaduk, Christopher Sundling, Anna Färnert, Carolina Bernhardsson, Maximilian Larena, Mattias Jakobsson, Gunilla B. Karlsson Hedestam
The human T cell receptor (TCR) genes are critical for mediating immune responses to pathogens, tumors and regulating self-antigen recognition. A detailed analysis and validation of expressed TCR alpha, beta, gamma, and delta genes in 45 donors from
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::ab163abfd86539a43ad3355bdb5f0c9b
https://doi.org/10.1101/2022.08.25.505097
https://doi.org/10.1101/2022.08.25.505097
Autor:
Martin Corcoran, Mark Chernyshev, Marco Mandolesi, Sanjana Narang, Mateusz Kaduk, Kewei Ye, Christopher Sundling, Anna Färnert, Taras Kreslavsky, Carolina Bernhardsson, Maximilian Larena, Mattias Jakobsson, Gunilla B. Karlsson Hedestam
Publikováno v:
Immunity. 56:635-652.e6
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::e4b87e91dfdff7c095ce69c4069854c5
https://doi.org/10.1016/j.immuni.2023.01.026
https://doi.org/10.1016/j.immuni.2023.01.026
Publikováno v:
Frontiers in immunology. 13
The accurate germline gene assignment and assessment of somatic hypermutation in antibodies induced by immunization or infection are important in immunological studies. Here, we illustrate issues specific to the construction of comprehensive immunogl
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::6116359fa89899780cce68465fba061f
https://pubmed.ncbi.nlm.nih.gov/35419009
https://pubmed.ncbi.nlm.nih.gov/35419009
Autor:
Xaquin Castro Dopico, Pauline Maisonasse, Mateusz Kaduk, Nathalie Dereuddre-Bosquet, Izabela Nowak, Ben Murrell, Martin Corcoran, Néstor Vázquez Bernat, Sanjana Narang, Gunilla B. Karlsson Hedestam
Publikováno v:
SSRN Electronic Journal.
Rhesus and cynomolgus macaques are important animal models for the pre-clinical assessment of candidate drugs and vaccines. Four main sub-groups are used: Indian and Chinese origin rhesus macaques and Mauritian and Indonesian cynomolgus macaques. Her
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::a731dfd277d92c8ce0e59ca0771ca22d
https://doi.org/10.2139/ssrn.3651514
https://doi.org/10.2139/ssrn.3651514
Autor:
Mateusz Kaduk, Erik L. L. Sonnhammer
Publikováno v:
Bioinformatics. 33:1154-1159
Motivation The initial step in many orthology inference methods is the computationally demanding establishment of all pairwise protein similarities across all analysed proteomes. The quadratic scaling with proteomes has become a major bottleneck. A r
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::43c73d5812be0b6ba6203702f4641df6
https://doi.org/10.1093/bioinformatics/btw774
https://doi.org/10.1093/bioinformatics/btw774