Výsledky vyhledávání - "Mateusz Dezor"

Original article Mutations in the exon 7 of Trp53 gene and the level of p53 protein in double transgenic mouse model of Alzheimer’s disease

Autor: Monika Suwalska, Mateusz Dezor, Margarita Lianeri, Jolanta Dorszewska, Wojciech Kozubski, Anna Oczkowska, Agata Rozycka, Jolanta Florczak-Wyspianska, Michał J. Kowalczyk, Michal Prendecki, Paweł P. Jagodziński

Publikováno v: Folia Neuropathologica. 1:30-40

Alzheimer's disease (AD) leads to generation of β-amyloid (Aβ) in the brain. Alzheimer's disease model PS/APP mice show a markedly accelerated accumulation of Aβ, which may lead to apoptosis induction e.g. in cells expressing wild-type p53. The TP

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::0dc4cef683fd6853b54f91289c9552bc
https://doi.org/10.5114/fn.2014.41742

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Mutations of TP53 Gene and Oxidative Stress in Alzheimer’s Disease Patients

Autor: Wojciech Kozubski, Izabela Postrach, Jolanta Dorszewska, Anna Oczkowska, Jolanta Florczak-Wyspianska, Paweł P. Jagodziński, Michal Prendecki, Agata Rozycka, Mateusz Dezor

Publikováno v: Advances in Alzheimer's Disease. :24-32

Alzheimer’s disease (AD) leads to the generation of β-amyloid (Aβ), which may damage DNA and thus lead to apoptosis induction by the p53 pathway. Dysfunction of the p53 protein may then be connected with the development of AD. Studies were conduc

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::39c8f89bc4fde5b415400c55eb961fa3
https://doi.org/10.4236/aad.2014.31004

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Homocysteine and asymmetric dimethylarginine concentrations in the plasma of Alzheimer’s disease patients with varying degrees of dementia

Autor: Mateusz Dezor, Wojciech Kozubski, Anna Oczkowska, Jolanta Florczak-Wyspianska, Jolanta Dorszewska, Michal Prendecki

Publikováno v: Advances in Alzheimer's Disease. :1-6

Alzheimer’s disease (AD) is accompanied by elevated levels of homocysteine (Hcy). Homocysteine may induce elevated concentration of asymmetric dimethylarginine (ADMA). Both Hcy and ADMA are the amino acids thought to represent risk factors of vascu

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::cf0c2b83fb9c418708f5ac58e52c9e65
https://doi.org/10.4236/aad.2013.21001

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Molecular Basis of Familial and Sporadic Alzheimer's Disease

Autor: Mateusz Dezor, Anna Oczkowska, Wojciech Kozubski, Michal Prendecki, Jolanta Dorszewska

Publikováno v: Current Alzheimer research. 13(9)

Alzheimer's disease (AD) is a multifactorial disease with genetic (70%) and environmental (30%) causes. Among the genetic factors are genes associated with a family history of the disease (familial AD, FAD) and sporadic AD (SAD). The genes: APP (amyl

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::cb6606401c675601c24b2554d01d442b
https://pubmed.ncbi.nlm.nih.gov/26971934

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P3‐124: APOLIPOPROTEIN E GENOTYPE AND OXIDATIVE STRESS IN PERIPHERAL LYMPHOCYTES OF PATIENTS WITH ALZHEIMER'S DISEASE

Autor: Jolanta Dorszewska, Marta Kowalska, Mateusz Dezor, Izabela Postrach, Wojciech Kozubski, Michal Prendecki, Jolanta Florczak, Anna Polrolniczak

Publikováno v: Alzheimer's & Dementia. 10

OXIDATIVE STRESS IN PERIPHERAL LYMPHOCYTES OF PATIENTS WITH ALZHEIMER’S DISEASE Jolanta Dorszewska, Anna Polrolniczak, Michal Prendecki, Jolanta Florczak, Mateusz Dezor, Marta Kowalska, Izabela Postrach, Wojciech Kozubski, Laboratory of Neurobiolog

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::0b3fe0044e807cfcce86e549b9e0ea14
https://doi.org/10.1016/j.jalz.2014.05.1213

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Mutations in the exon 7 of Trp53 gene and the level of p53 protein in double transgenic mouse model of Alzheimer's disease

Autor: Jolanta, Dorszewska, Anna, Oczkowska, Monika, Suwalska, Agata, Rozycka, Jolanta, Florczak-Wyspianska, Mateusz, Dezor, Margarita, Lianeri, Paweł P, Jagodzinski, Michal J, Kowalczyk, Michal, Prendecki, Wojciech, Kozubski

Publikováno v: Folia neuropathologica. 52(1)

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::980c1e6ba05cc02ab602e3418bc5488a
https://pubmed.ncbi.nlm.nih.gov/24729341

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P3–044: Mutations of TP53 C708T and C748A, oxidative DNA damage, and p53 and OGG1 protein levels in peripheral lymphocytes of the people with Alzheimer's disease

Autor: Jolanta Dorszewska, Jolanta Florczak, Anna Oczkowska, Mateusz Dezor, Wojciech Kozubski

Publikováno v: Alzheimer's & Dementia. 9

Background: We have previously reported an increased susceptibility to cell death of lymphocytes obtained from patients with Alzheimer’s disease (AD) when exposed to oxidative stress induced by hydrogen peroxide (H2O2). Herewe investigated whether

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::1214502a9e4dfee28c67f9f1cbe653a4
https://doi.org/10.1016/j.jalz.2013.05.1113

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Expression of 8-oxoguanine DNA glycosylase 1 (OGG1) and the level of p53 and TNF-αlpha proteins in peripheral lymphocytes of patients with Alzheimer's disease

Autor: Mateusz, Dezor, Jolanta, Dorszewska, Jolanta, Florczak, Bartosz, Kempisty, Joanna, Jaroszewska-Kolecka, Agata, Rozycka, Anna, Polrolniczak, Robert, Bugaj, Paweł P, Jagodzinski, Wojciech, Kozubski

Publikováno v: Folia neuropathologica. 49(2)

The aim of the study was to determine the extent of oxidative DNA damage (levels of 8-oxo2dG) and expression of OGG1 and p53 and TNF-α proteins in lymphocytes of Alzheimer's disease (AD) patients and a control group. The studies were conducted on 41

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::6ea19154c1422f91e1ad9524b664536c
https://pubmed.ncbi.nlm.nih.gov/21845541

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