Zobrazeno 1 - 10
of 240
pro vyhledávání: '"Mateo Ignacio"'
Autor:
Berciano José, Valdivieso Fernando, Frank-García Ana, Dobato José L, Calero Miguel, Pozueta Ana, Rodríguez-Rodríguez Eloy, Sánchez-Juan Pascual, Mateo Ignacio, Vázquez-Higuera José L, Bullido Maria J, Combarros Onofre
Publikováno v:
BMC Research Notes, Vol 4, Iss 1, p 327 (2011)
Abstract Background Tau abnormal hyperphosphorylation and the formation of neurofibrillary tangles in AD brain is the result of upregulation of tau kinases and downregulation of tau phosphatases. Methods In a group of 729 Spanish late-onset Alzheimer
Externí odkaz:
https://doaj.org/article/d0c5ed539cee41988dd42e2b43cc0c3f
Autor:
Berciano José, González-Perez Soraya, Sánchez-Juan Pascual, Mateo Ignacio, Vazquez-Higuera José, Rodríguez-Rodríguez Eloy, Pozueta Ana, Combarros Onofre
Publikováno v:
BMC Neurology, Vol 11, Iss 1, p 78 (2011)
Abstract Background Mild cognitive impairment (MCI) is a heterogeneous clinical entity that comprises the prodromal phase of Alzheimer's disease (Pr-AD). New biomarkers are useful in detecting Pr-AD, but they are not universally available. We aimed t
Externí odkaz:
https://doaj.org/article/4231a5d030ea4b69a94ca1146cfb2624
Autor:
Arias-Vásquez Alejandro, Oulhaj Abderrahim, Mateo Ignacio, Kölsch Heike, Heun Reinhard, Gwilliam Rhian, Deloukas Panos, Alvarez Victoria, Coto Eliecer, Barber Rachel, Kehoe Patrick G, Brown Kristelle, Wilcock Gordon K, Lehmann Michael G, Belbin Olivia, Cortina-Borja Mario, Hammond Naomi, Warden Donald R, Combarros Onofre, Schuur Maaike, Aulchenko Yurii S, Ikram M Arfan, Breteler Monique M, van Duijn Cornelia M, Morgan Kevin, Smith A David, Lehmann Donald J
Publikováno v:
BMC Medical Genetics, Vol 11, Iss 1, p 162 (2010)
Abstract Background The loss of noradrenergic neurones of the locus coeruleus is a major feature of Alzheimer's disease (AD). Dopamine β-hydroxylase (DBH) catalyses the conversion of dopamine to noradrenaline. Interactions have been reported between
Externí odkaz:
https://doaj.org/article/66ad3f08c18d45f192ef9b609d1c1ab5
Autor:
Berciano José, Valdivieso Fernando, Frank Ana, Martínez-García Ana, Pozueta Ana, Mateo Ignacio, Sánchez-Juan Pascual, Rodríguez-Rodríguez Eloy, Vázquez-Higuera José, Bullido María J, Combarros Onofre
Publikováno v:
BMC Medical Genetics, Vol 11, Iss 1, p 32 (2010)
Abstract Background Interleukin (IL)-1β is a potent proinflammatory cytokine markedly overexpressed in the brains of patients with Alzheimer's disease (AD), and also involved in development of atherosclerosis and coronary artery disease. Caspase-1 (
Externí odkaz:
https://doaj.org/article/fe624452a1f0472a95740bf8f9b4a78c
Autor:
Berciano José, Valdivieso Fernando, Sastre Isabel, Frank Ana, Pozueta Ana, Mateo Ignacio, Rodríguez-Rodríguez Eloy, Sánchez-Juan Pascual, Vázquez-Higuera José, Bullido María J, Combarros Onofre
Publikováno v:
BMC Medical Genetics, Vol 10, Iss 1, p 129 (2009)
Abstract Background As dual-specificity tyrosine phosphorylation-regulated kinase 1A (DYRK1A) has been implicated in the abnormal hyperphosphorylation of tau in Alzheimer's disease (AD) brain, and the development of neurofibrillary tangles, we examin
Externí odkaz:
https://doaj.org/article/4e4ff2708af54e58b6c0ee0f6f042be2
Autor:
Alvarez Victoria, Coto Eliecer, Harrison Rachel, Kehoe Patrick G, Brown Kristelle, Wilcock Gordon K, Heun Reinhard, Kölsch Heike, Schuur Maaike, Aulchenko Yurii S, Lehmann Michael G, Cortina-Borja Mario, Arias-Vásquez Alejandro, Belbin Olivia, Hammond Naomi, van Duijn Cornelia M, Combarros Onofre, Deloukas Panos, Mateo Ignacio, Gwilliam Rhian, Morgan Kevin, Warden Donald R, Smith A David, Lehmann Donald J
Publikováno v:
Journal of Neuroinflammation, Vol 6, Iss 1, p 22 (2009)
Abstract Background Chronic inflammation is a characteristic of Alzheimer's disease (AD). An interaction associated with the risk of AD has been reported between polymorphisms in the regulatory regions of the genes for the pro-inflammatory cytokine,
Externí odkaz:
https://doaj.org/article/97355f3697ac4db1a04ed72d195c6a12
Autor:
Combarros Onofre, Berciano José, Infante Jon, Rodríguez-Rodríguez Eloy, Sánchez-Juan Pascual, Mateo Ignacio, Vázquez-Higuera José
Publikováno v:
BMC Medical Genetics, Vol 10, Iss 1, p 68 (2009)
Abstract Background As cyclin-dependent kinase 5 (CDK5) has been implicated in the abnormal hyperphosphorylation of tau in Alzheimer's disease (AD) brain, and the development of neurofibrillary tangles, we examined the contribution of this gene to th
Externí odkaz:
https://doaj.org/article/df412130cc1b4f88aeca5cdb8b6a4876
Autor:
Rodríguez-Rodríguez, Eloy, Mateo, Ignacio, Infante, Jon, Llorca, Javier, García-Gorostiaga, Inés, Vázquez-Higuera, José Luis, Sánchez-Juan, Pascual, Berciano, José, Combarros, Onofre ⁎
Publikováno v:
In Brain Research 2009 1280:166-171
Autor:
Rodríguez-Rodríguez, Eloy, Sánchez-Juan, Pascual, Mateo, Ignacio, Infante, Jon, Sánchez-Quintana, Coro, García-Gorostiaga, Inés, Berciano, José, Combarros, Onofre
Publikováno v:
In Journal of the Neurological Sciences 2008 264(1):97-99
Autor:
García-Moncó, Juan Carlos, Pinedo, Ana, Escalza, Inés, Ferreira, Eva, Foncea, Nerea, Gómez-Beldarrain, Marian, Ruiz-Ojeda, Javier, Mateo, Ignacio, Mediavilla, Javier, Basterretxea, Jose M.
Publikováno v:
In Clinical Neurology and Neurosurgery 2007 109(1):50-53