Zobrazeno 1 - 10
of 36
pro vyhledávání: '"Mateo I. Sánchez"'
Autor:
Eric T. Strand, Robert Coukos, David Yao, Michael C. Bassik, Alice Y. Ting, Mateo I. Sánchez, Jonathan S. Weissman
The trafficking of specific protein cohorts to the correct subcellular location at the correct time is essential for every signaling and regulatory process in biology. Gene perturbation screens could provide a powerful approach to probe the molecular
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::692875215b813cd289cb22951ff5d4a9
https://doi.org/10.1101/2021.04.11.439362
https://doi.org/10.1101/2021.04.11.439362
Publikováno v:
Proc Natl Acad Sci U S A
Molecular integrators, in contrast to real-time indicators, convert transient cellular events into stable signals that can be exploited for imaging, selection, molecular characterization, or cellular manipulation. Many integrators, however, are desig
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::42f8efab2cecd81d00bf2a4393e152bb
https://europepmc.org/articles/PMC7777206/
https://europepmc.org/articles/PMC7777206/
Autor:
Paul Hoerbelt, Alice Y. Ting, Robert C. Malenka, Mateo I. Sánchez, Karl Deisseroth, Christina K. Kim, Lief E. Fenno
SUMMARYThe ability to record transient cellular events in the DNA or RNA of cells would enable precise, large-scale analysis, selection, and reprogramming of heterogeneous cell populations. Here we report a molecular technology for stable genetic tag
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::6b13111018b19e300db62f446870722f
https://doi.org/10.1101/2020.11.01.364174
https://doi.org/10.1101/2020.11.01.364174
Autor:
Karl Deisseroth, Lief E. Fenno, Robert C. Malenka, Paul Hoerbelt, Alice Y. Ting, Mateo I. Sánchez, Christina K. Kim
Publikováno v:
Cell. 183(7)
The ability to record transient cellular events in the DNA or RNA of cells would enable precise, large-scale analysis, selection, and reprogramming of heterogeneous cell populations. Here, we report a molecular technology for stable genetic tagging o
Autor:
Ezequiel Perez-Inestrosa, Yolanda Vida, M. Eugenio Vázquez, José L. Mascareñas, Mateo I. Sánchez, Ayumu Sugiura, José Martínez-Costas
Publikováno v:
Scientific Reports
Scientific Reports, Vol 10, Iss 1, Pp 1-12 (2020)
Minerva. Repositorio Institucional de la Universidad de Santiago de Compostela
instname
Scientific Reports, Vol 10, Iss 1, Pp 1-12 (2020)
Minerva. Repositorio Institucional de la Universidad de Santiago de Compostela
instname
MitoBlue is a fluorescent bisamidine that can be used to easily monitor the changes in mitochondrial degradation processes in different cells and cellular conditions. MitoBlue staining pattern is exceptional among mitochondrial dyes and recombinant f
Autor:
Mateo I. Sánchez, Edgar Deu, Dara Davison, Ambrosius P. Snijders, Bethany M. Anderson, Michele S. Y. Tan, Laura E. Edgington-Mitchell, Stephen Howell
Publikováno v:
PLoS ONE
PLoS ONE, Vol 15, Iss 1, p e0227341 (2020)
PLoS ONE, Vol 15, Iss 1, p e0227341 (2020)
Clan CA cysteine proteases, also known as papain-like proteases, play important roles throughout the malaria parasite life cycle and are therefore potential drug targets to treat this disease and prevent its transmission. In order to study the biolog
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::73e015a788ee78f6917f3d9c2c26fc57
Autor:
Kenny K. H. Ang, Michelle R. Arkin, Matthew Bogyo, Edgar Deu, Steven Chen, Laura E. de Vries, Mateo I. Sánchez, Christine Lehmann, Jeong T. Lee, Christopher W. Wilson
Publikováno v:
PLoS ONE
PLoS ONE, Vol 14, Iss 12, p e0226270 (2019)
PloS one, vol 14, iss 12
PLoS One, 14
PLoS One, 14, 12
PLoS ONE, Vol 14, Iss 12, p e0226270 (2019)
PloS one, vol 14, iss 12
PLoS One, 14
PLoS One, 14, 12
Dipeptidyl aminopeptidases (DPAPs) are cysteine proteases that cleave dipeptides from the N-terminus of protein substrates and have been shown to play important roles in many pathologies including parasitic diseases such as malaria, toxoplasmosis and
Autor:
Craig P. Wildes, Mateo I. Sánchez, Tanyaporn Pattarabanjird, Alice Y. Ting, Gillian A. Matthews, Wenjing Wang, Gordon F. Glober, Kay M. Tye
Publikováno v:
Nature biotechnology
PMC
PMC
Activity remodels neurons, altering their molecular, structural, and electrical characteristics. To enable the selective characterization and manipulation of these neurons, we present FLARE, an engineered transcription factor that drives expression o
Autor:
Mateo I. Sánchez, Gustavo Rama, Renata Calo, Kübra Ucar, Per Lincoln, Miguel Vázquez López, Manuel Melle-Franco, José Luis Mascareñas, M. Eugenio Vázquez
We report the first Ru(II) coordination compounds that interact with DNA through a canonical minor groove insertion mode and with selectivity for A/T rich sites. This was made possible by integrating a bis‑benzamidine minor groove DNA-binding agent
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::09c6f2918f2dbf5bf4400b91a2119647
https://doi.org/10.26434/chemrxiv.8118995
https://doi.org/10.26434/chemrxiv.8118995
Autor:
Marcin Drag, Fang Yuan, Katarzyna Groborz, Martin Horn, Edgar Deu, Chrislaine Withers-Martinez, Laurie Kuppens, Neysa Nevins, Shirin Arastu-Kapur, Matthew Bogyo, Michael Mareš, Mateo I. Sánchez, Christine Lehmann, David Jonathan Hirst, Marcin Poreba, Laura E. de Vries
Publikováno v:
FEBS Journal, 286, 20, pp. 3998-4023
The Febs Journal
FEBS Journal, 286, 3998-4023
The Febs Journal
FEBS Journal, 286, 3998-4023
Malarial dipeptidyl aminopeptidases (DPAPs) are cysteine proteases important for parasite development thus making them attractive drug targets. In order to develop inhibitors specific to the parasite enzymes, it is necessary to map the determinants o
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::119003c3d9face13e10fdaba3ed3a2db
https://hdl.handle.net/2066/209409
https://hdl.handle.net/2066/209409